{
  "id": 4896,
  "label": "intestinal neuroendocrine neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002883",
  "properties": {
    "xrefs": [
      "DOID:4119",
      "GARD:0023287",
      "MEDGEN:233567",
      "NCIT:C5695",
      "UMLS:C1334231"
    ],
    "synonyms": [
      "intestinal neuroendocrine neoplasm",
      "intestine NET",
      "intestine neuroendocrine neoplasm",
      "intestine neuroendocrine tumor",
      "intestine neuroendocrine tumor, well differentiated, low or intermediate grade",
      "intestine neuroendocrine tumour",
      "neuroendocrine neoplasm of intestine",
      "neuroendocrine neoplasm of the intestine",
      "intestinal neuroendocrine benign tumor",
      "intestinal neuroendocrine benign tumour"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A neoplasm with neuroendocrine differentiation that arises from the small or large intestine. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 20357,
      "label": "intestinal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6756,
        20434
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4610",
          "MEDGEN:43932",
          "NCIT:C3141",
          "ONCOTREE:BOWEL",
          "SCTID:126769007",
          "UMLS:C0021841"
        ],
        "synonyms": [
          "intestinal neoplasm",
          "intestinal neoplasms",
          "intestinal tumor",
          "intestinal tumors",
          "intestinal tumour",
          "intestinal tumours",
          "intestine neoplasm",
          "intestine neoplasm (disease)",
          "intestine tumor",
          "intestine tumour",
          "neoplasm of intestine",
          "neoplasm of intestines",
          "neoplasm of the intestines",
          "tumor of intestine",
          "tumor of intestines",
          "tumor of the intestines",
          "tumour of intestine",
          "tumour of intestines",
          "tumour of the intestines",
          "bowel neoplasm",
          "intestinal benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm involving the small or large intestine."
      },
      "child_count": 12,
      "reference_id": "MONDO:0021118"
    },
    {
      "id": 21456,
      "label": "digestive system neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6151,
        19314,
        20434
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0002437",
          "MEDGEN:232237",
          "MESH:C535650",
          "NCIT:C27721",
          "Orphanet:100092",
          "UMLS:C1333799"
        ],
        "synonyms": [
          "alimentary part of gastrointestinal system NET",
          "alimentary part of gastrointestinal system neuroendocrine neoplasm",
          "alimentary part of gastrointestinal system neuroendocrine tumor",
          "alimentary part of gastrointestinal system neuroendocrine tumor, well differentiated, low or intermediate grade",
          "alimentary part of gastrointestinal system neuroendocrine tumour",
          "carcinoid tumor of digestive system",
          "carcinoid tumour of digestive system",
          "digestive system NET",
          "digestive system neuroendocrine neoplasm",
          "digestive system neuroendocrine tumor",
          "digestive system neuroendocrine tumor, well differentiated, low or intermediate grade",
          "digestive system neuroendocrine tumour",
          "gastro-enteropancreatic neuroendocrine tumor",
          "gastro-enteropancreatic neuroendocrine tumour",
          "gastroenteropancreatic endocrine tumor",
          "gastroenteropancreatic endocrine tumour",
          "gastroenteropancreatic neuroendocrine neoplasm",
          "gastrointestinal neuroendocrine neoplasm",
          "gastrointestinal system neuroendocrine neoplasm",
          "neuroendocrine neoplasm of alimentary part of gastrointestinal system",
          "neuroendocrine neoplasm of digestive system",
          "GEP tumors",
          "GEP tumours",
          "GEP-NEN",
          "GEP-NET",
          "carcinoid tumor",
          "carcinoid tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm with neuroendocrine differentiation arising from the digestive system. It includes neuroendocrine tumors (well-differentiated endocrine tumors or carcinoid tumors and well differentiated endocrine carcinomas) and neuroendocrine carcinomas (poorly differentiated neuroendocrine carcinomas, small cell carcinomas, and large cell neuroendocrine carcinomas)."
      },
      "child_count": 21,
      "reference_id": "MONDO:0024503"
    }
  ],
  "children": [
    {
      "id": 4895,
      "label": "colon neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4896,
        7078
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4118",
          "GARD:0019755",
          "MEDGEN:234162",
          "NCIT:C5697",
          "Orphanet:100080",
          "UMLS:C1333097",
          "icd11.foundation:144503516"
        ],
        "synonyms": [
          "colon NET",
          "colon neuroendocrine neoplasm",
          "colon neuroendocrine tumor",
          "colon neuroendocrine tumor, well differentiated, low or intermediate grade",
          "colon neuroendocrine tumour",
          "colonic neuroendocrine neoplasm",
          "colonic neuroendocrine tumour",
          "neuroendocrine neoplasm of colon",
          "neuroendocrine neoplasm of the colon",
          "neuroendocrine tumor of the colon",
          "neuroendocrine tumour of the colon"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm with neuroendocrine differentiation that arises from the colon. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade)."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002882"
    },
    {
      "id": 5534,
      "label": "rectum neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4896,
        21431
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5777",
          "GARD:0019756",
          "MEDGEN:277576",
          "NCIT:C5698",
          "UMLS:C1335686",
          "icd11.foundation:1619951900"
        ],
        "synonyms": [
          "neuroendocrine neoplasm of rectum",
          "neuroendocrine neoplasm of the rectum",
          "rectal neuroendocrine neoplasm",
          "rectum neuroendocrine neoplasm",
          "NET of the rectum",
          "neuroendocrine tumor of rectum",
          "neuroendocrine tumour of rectum",
          "rectal NET",
          "rectal neuroendocrine tumor",
          "rectum NET",
          "rectum neuroendocrine tumor",
          "rectum neuroendocrine tumor, well differentiated, low or intermediate grade",
          "rectum neuroendocrine tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm with neuroendocrine differentiation that arises from the rectum. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade)."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003646"
    },
    {
      "id": 18542,
      "label": "small intestine neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4896,
        6071
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4434",
          "EFO:1001928",
          "GARD:0021765",
          "MEDGEN:233453",
          "NCIT:C5803",
          "Orphanet:423975",
          "UMLS:C1336005"
        ],
        "synonyms": [
          "NET of the small intestine",
          "neuroendocrine neoplasm of small intestine",
          "neuroendocrine neoplasm of the small intestine",
          "neuroendocrine tumor of small bowel",
          "neuroendocrine tumour of small bowel",
          "small intestinal neuroendocrine neoplasm",
          "small intestine NET",
          "small intestine neuroendocrine neoplasm",
          "small intestine neuroendocrine tumor",
          "small intestine neuroendocrine tumour",
          "neuroendocrine tumor of the small intestine",
          "neuroendocrine tumour of the small intestine",
          "small intestine neuroendocrine tumor, well differentiated, low or intermediate grade"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm with neuroendocrine differentiation that arises from the small intestine. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade)."
      },
      "child_count": 6,
      "reference_id": "MONDO:0018510"
    },
    {
      "id": 20650,
      "label": "intestinal neuroendocrine tumor G1",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2885,
        4896,
        7051
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025331",
          "MEDGEN:138099",
          "MESH:C562842",
          "NCIT:C4637",
          "OMIM:114900",
          "SCTID:276816003",
          "UMLS:C0349535"
        ],
        "synonyms": [
          "carcinoid tumor of intestine",
          "carcinoid tumor of the intestine",
          "carcinoid tumour of intestine",
          "carcinoid tumour of the intestine",
          "grade 1 neuroendocrine neoplasm of intestine",
          "intestinal NET G1",
          "intestinal carcinoid tumor",
          "intestinal carcinoid tumour",
          "intestinal neuroendocrine tumor G1",
          "intestine NET G1",
          "intestine carcinoid tumor",
          "intestine carcinoid tumor (disease)",
          "intestine carcinoid tumour",
          "intestine carcinoid tumour (disease)",
          "intestine neuroendocrine neoplasm G1",
          "intestine neuroendocrine tumor, well differentiated, low grade"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A well differentiated, low grade neuroendocrine tumor (carcinoid tumor) that arises from the small or large intestine. The mitotic count is less than 2 per 10 HPF and/or the Ki67 index is equal to or less than 2 percent."
      },
      "child_count": 6,
      "reference_id": "MONDO:0021533"
    }
  ],
  "roots": [
    {
      "id": 20357,
      "label": "intestinal neoplasm"
    },
    {
      "id": 21456,
      "label": "digestive system neuroendocrine neoplasm"
    }
  ]
}