{
  "id": 4903,
  "label": "skull base chordoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002892",
  "properties": {
    "xrefs": [
      "DOID:4151",
      "GARD:0023290",
      "MEDGEN:233448",
      "NCIT:C5453",
      "UMLS:C1335975"
    ],
    "synonyms": [
      "chordoma of skull base",
      "chordoma of the skull base",
      "skull base chordoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "A slow-growing malignant bone tumor arising from the remnants of the notochord and occurring in the base of the skull. It is characterized by a lobulated growth pattern, myxoid stroma formation, and the presence of physaliphorous cells.."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 4265,
      "label": "skull cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4262,
        7266,
        21561
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1863",
          "GARD:0023073",
          "MEDGEN:1662558",
          "NCIT:C155790",
          "UMLS:C2062986"
        ],
        "synonyms": [
          "cancer of skull",
          "malignant neoplasm of skull",
          "malignant skull neoplasm",
          "skull cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the skull."
      },
      "child_count": 18,
      "reference_id": "MONDO:0002132"
    },
    {
      "id": 4813,
      "label": "skull base neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21561
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3842",
          "GARD:0023244",
          "MEDGEN:138208",
          "MESH:D019292",
          "NCIT:C4676",
          "UMLS:C0376527"
        ],
        "synonyms": [
          "basicranium neoplasm",
          "basicranium neoplasm (disease)",
          "basicranium tumor",
          "basicranium tumour",
          "neoplasm of basicranium",
          "neoplasm of skull base",
          "neoplasm of the skull base",
          "skull base neoplasm",
          "skull base tumor",
          "skull base tumour",
          "tumor of basicranium",
          "tumor of skull base",
          "tumor of the skull base",
          "tumour of basicranium",
          "tumour of skull base",
          "tumour of the skull base",
          "tumours of skull base",
          "skull base cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the skull base."
      },
      "child_count": 5,
      "reference_id": "MONDO:0002785"
    },
    {
      "id": 10236,
      "label": "chordoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4653
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3302",
          "GARD:0001303",
          "HP:0010762",
          "ICDO:9370/3",
          "MEDGEN:40277",
          "MESH:D002817",
          "MedDRA:10008747",
          "NANDO:2200098",
          "NCIT:C2947",
          "NORD:931",
          "OMIM:215400",
          "ONCOTREE:CHDM",
          "Orphanet:178",
          "UMLS:C0008487",
          "icd11.foundation:898231522"
        ],
        "synonyms": [
          "chordoma",
          "chordoma (disease)",
          "chordoma, malignant",
          "notochordal sarcoma",
          "CHDM",
          "chordoma, susceptibility to",
          "susceptibility to chordoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "Chordomas are rare malignant tumors arising from embryonic remnants of the notochord in axial skeleton."
      },
      "child_count": 4,
      "reference_id": "MONDO:0008978"
    }
  ],
  "children": [
    {
      "id": 5716,
      "label": "clivus chordoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4903
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6312",
          "GARD:0023692",
          "ICD9:170.0",
          "MEDGEN:232372",
          "NCIT:C5412",
          "SCTID:446939001",
          "UMLS:C1333071"
        ],
        "synonyms": [
          "chordoma (disease) of clivus of occipital bone",
          "chordoma of clivus",
          "chordoma of the clivus",
          "clival chordoma",
          "clivus of occipital bone chordoma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A slow-growing malignant bone tumor arising from the remnants of the notochord and occurring in the clivus. It is characterized by a lobulated growth pattern, myxoid stroma formation, and the presence of physaliphorous cells."
      },
      "child_count": 1,
      "reference_id": "MONDO:0003849"
    }
  ],
  "roots": [
    {
      "id": 4265,
      "label": "skull cancer"
    },
    {
      "id": 4813,
      "label": "skull base neoplasm"
    },
    {
      "id": 10236,
      "label": "chordoma"
    }
  ]
}