{
  "id": 4907,
  "label": "skin cancer",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002898",
  "properties": {
    "xrefs": [
      "DOID:4159",
      "ICD10CM:C43-C44",
      "ICD9:173.8",
      "ICD9:173.9",
      "MEDGEN:40101",
      "NCIT:C2920",
      "SCTID:372130007",
      "UMLS:C0007114",
      "icd11.foundation:1706880799"
    ],
    "synonyms": [
      "cancer of zone of skin",
      "malignant neoplasm of skin",
      "malignant neoplasm of the skin",
      "malignant neoplasm of zone of skin",
      "malignant skin neoplasm",
      "malignant skin tumor",
      "malignant skin tumour",
      "malignant tumor of skin",
      "malignant tumor of the skin",
      "malignant tumour of skin",
      "malignant tumour of the skin",
      "malignant zone of skin neoplasm",
      "melanoma and non-melanoma skin cancer",
      "skin cancer",
      "skin cancer, Including melanoma",
      "skin neoplasm, malignant",
      "zone of skin cancer"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "A malignant neoplasm involving the zone of skin"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 13,
  "parents": [
    {
      "id": 3053,
      "label": "integumentary system cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4198,
        6733
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060122"
        ],
        "synonyms": [
          "cancer of integumental system",
          "integumental system cancer",
          "malignant integumental system neoplasm",
          "malignant neoplasm of integumental system"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the integumental system"
      },
      "child_count": 14,
      "reference_id": "MONDO:0000653"
    },
    {
      "id": 4599,
      "label": "skin neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798,
        6820
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3165",
          "EFO:0004198",
          "ICD9:239.2",
          "MEDGEN:19993",
          "MESH:D012878",
          "NCIT:C3372",
          "ONCOTREE:SKIN",
          "SCTID:126488004",
          "UMLS:C0037286"
        ],
        "synonyms": [
          "neoplasm of skin",
          "neoplasm of the skin",
          "neoplasm of zone of skin",
          "skin neoplasm",
          "skin neoplasms",
          "skin tumor",
          "skin tumour",
          "tumor of skin",
          "tumor of the skin",
          "tumor of zone of skin",
          "tumour of skin",
          "tumour of the skin",
          "tumour of zone of skin",
          "zone of skin neoplasm",
          "zone of skin neoplasm (disease)",
          "zone of skin tumor",
          "zone of skin tumour",
          "skin",
          "skin benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A benign or malignant tumor involving the skin. Representative examples of benign skin neoplasms include the benign melanocytic skin nevus, acanthoma, sebaceous adenoma, sweat gland adenoma, lipoma, hemangioma, fibroma, and benign fibrous histiocytoma. Representative examples of malignant skin neoplasms include basal cell carcinoma, squamous cell carcinoma, melanoma, and Kaposi sarcoma."
      },
      "child_count": 34,
      "reference_id": "MONDO:0002531"
    }
  ],
  "children": [
    {
      "id": 3624,
      "label": "labium majus cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3735,
        4907
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11905",
          "GARD:0027576",
          "ICD9:184.1",
          "MEDGEN:96920",
          "NCIT:C7638",
          "SCTID:363446004",
          "UMLS:C0496814"
        ],
        "synonyms": [
          "cancer of labium majora",
          "labium majora cancer",
          "malignant labia majora neoplasm",
          "malignant labia majora tumor",
          "malignant labia majora tumour",
          "malignant labium majora neoplasm",
          "malignant neoplasm of labia majora",
          "malignant neoplasm of labium majora",
          "malignant neoplasm of the labia majora",
          "malignant tumor of labia majora",
          "malignant tumor of the labia majora",
          "malignant tumour of labia majora",
          "malignant tumour of the labia majora"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the labium majora."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001403"
    },
    {
      "id": 3733,
      "label": "labia minora cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3735,
        4907
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1243",
          "GARD:0027580",
          "ICD10CM:C51.1",
          "ICD9:184.2",
          "MEDGEN:96921",
          "NCIT:C7637",
          "SCTID:363447008",
          "UMLS:C0496815"
        ],
        "synonyms": [
          "cancer of labium minora",
          "labium minora cancer",
          "malignant labia minora neoplasm",
          "malignant labia minora tumor",
          "malignant labia minora tumour",
          "malignant labium minora neoplasm",
          "malignant neoplasm of labia minora",
          "malignant neoplasm of labium minora",
          "malignant neoplasm of labium minus",
          "malignant neoplasm of the labia minora",
          "malignant tumor of labia minora",
          "malignant tumor of the labia minora",
          "malignant tumour of labia minora",
          "malignant tumour of the labia minora"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A malignant neoplasm that affects the labia minora."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001526"
    },
    {
      "id": 3849,
      "label": "prepuce cancer",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4279,
        4907
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13168",
          "ICD10CM:C60.0",
          "ICD9:187.1",
          "MEDGEN:509336",
          "NCIT:C194356",
          "SCTID:363450006",
          "UMLS:C0153598",
          "icd11.foundation:272011035"
        ],
        "synonyms": [
          "cancer of prepuce",
          "malignant neoplasm of foreskin",
          "malignant neoplasm of prepuce",
          "malignant prepuce neoplasm",
          "malignant tumour of foreskin",
          "prepuce cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the prepuce."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001653"
    },
    {
      "id": 4329,
      "label": "sweat gland cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4478,
        4907
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2095",
          "MEDGEN:231171",
          "NCIT:C4810",
          "UMLS:C1321904"
        ],
        "synonyms": [
          "cancer of sweat gland",
          "malignant neoplasm of sweat gland",
          "malignant neoplasm of the sweat gland",
          "malignant sweat gland neoplasm",
          "malignant tumor of sweat gland",
          "malignant tumor of the sweat gland",
          "malignant tumour of sweat gland",
          "malignant tumour of the sweat gland",
          "sweat gland cancer",
          "sweat gland neoplasms, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A malignant neoplasm that affects the sweat glands."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002206"
    },
    {
      "id": 4404,
      "label": "cutaneous ganglioneuroma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4907,
        6767
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2425",
          "GARD:0023108",
          "MEDGEN:91077",
          "NCIT:C4481",
          "SCTID:254766004",
          "UMLS:C0346063"
        ],
        "synonyms": [
          "cutaneous ganglioneuroma",
          "ganglioneuroma of skin",
          "ganglioneuroma of the skin",
          "skin ganglioneuroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A ganglioneuroma arising from the skin."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002293"
    },
    {
      "id": 4707,
      "label": "skin carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4907,
        6734,
        20690
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3451",
          "EFO:0009259",
          "MEDGEN:195945",
          "NCIT:C4914",
          "UMLS:C0699893"
        ],
        "synonyms": [
          "carcinoma of skin",
          "carcinoma of the skin",
          "carcinoma of zone of skin",
          "non-melanoma cancer of skin",
          "non-melanoma cancer of the skin",
          "non-melanoma skin cancer",
          "nonmelanoma skin cancer",
          "skin cancer, non-melanoma",
          "skin carcinoma",
          "zone of skin carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A carcinoma that arises from epithelial cells of the zone of skin"
      },
      "child_count": 39,
      "reference_id": "MONDO:0002656"
    },
    {
      "id": 5298,
      "label": "malignant dermis tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4409,
        4907
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5274",
          "GARD:0023477",
          "MEDGEN:87564",
          "NCIT:C4574",
          "SCTID:255096006",
          "UMLS:C0346811"
        ],
        "synonyms": [
          "cancer of dermis",
          "dermis cancer",
          "malignant dermal neoplasm",
          "malignant dermis neoplasm",
          "malignant dermis tumor",
          "malignant neoplasm of dermis",
          "malignant neoplasm of the dermis",
          "malignant tumor of dermis",
          "malignant tumor of the dermis",
          "malignant tumour of the dermis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the dermis."
      },
      "child_count": 8,
      "reference_id": "MONDO:0003363"
    },
    {
      "id": 6237,
      "label": "skin meningioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4907,
        17113,
        20501
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8006",
          "GARD:0023999",
          "MEDGEN:698541",
          "UMLS:C1275260"
        ],
        "synonyms": [
          "meningioma (disease) of zone of skin",
          "zone of skin meningioma (disease)",
          "primary meningioma of the skin"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma (disease) that involves the zone of skin."
      },
      "child_count": 3,
      "reference_id": "MONDO:0004429"
    },
    {
      "id": 6750,
      "label": "cutaneous melanoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4907,
        6832,
        20680
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8923",
          "EFO:0000389",
          "HP:0012056",
          "ICD10CM:C43",
          "ICD9:172",
          "ICD9:172.0",
          "ICD9:172.2",
          "ICD9:172.3",
          "ICD9:172.4",
          "ICD9:172.5",
          "ICD9:172.8",
          "ICD9:172.9",
          "MEDGEN:57486",
          "NCIT:C3510",
          "ONCOTREE:SKCM",
          "SCTID:93655004",
          "UMLS:C0151779"
        ],
        "synonyms": [
          "cutaneous (skin) melanoma",
          "cutaneous melanoma",
          "cutaneous melanoma (disease)",
          "malignant cutaneous melanoma",
          "malignant melanoma (of skin), stage unspecified",
          "malignant melanoma of skin",
          "malignant melanoma of skin stage unspecified",
          "melanoma (disease) of zone of skin",
          "melanoma of skin",
          "melanoma of the skin",
          "skin melanoma",
          "skin, melanoma",
          "zone of skin melanoma",
          "zone of skin melanoma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A primary melanoma arising from atypical melanocytes in the skin. Precursor lesions include acquired and congenital melanocytic nevi, and dysplastic nevi. Several histologic variants have been recognized, including superficial spreading melanoma, acral lentiginous melanoma, nodular melanoma, and lentigo maligna melanoma."
      },
      "child_count": 30,
      "reference_id": "MONDO:0005012"
    },
    {
      "id": 18826,
      "label": "primary cutaneous lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4907,
        17548
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018698",
          "MEDGEN:220981",
          "MedDRA:10051708",
          "NCIT:C7162",
          "Orphanet:542",
          "SCTID:400001003",
          "UMLS:C1302772"
        ],
        "synonyms": [
          "cutaneous (skin) lymphoma",
          "primary cutaneous lymphoma",
          "primary skin lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Cutaneous lymphoma is a heterogeneous entity with respect to its clinical and pathological features, evolutive profile, prognosis, molecular etiology and response to therapy. These specifications have been taken into account in recent classifications, which have placed particular importance on the prognostic implications of these different entities."
      },
      "child_count": 6,
      "reference_id": "MONDO:0018898"
    },
    {
      "id": 19292,
      "label": "CD4+/CD56+ hematodermic neoplasm",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4907,
        6892,
        16517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081076",
          "EFO:0010580",
          "GARD:0010556",
          "ICD10CM:C86.4",
          "ICD9:202.80",
          "ICDO:9727/3",
          "MEDGEN:220972",
          "NCIT:C7203",
          "ONCOTREE:BPDCN",
          "Orphanet:86870",
          "SCTID:445105005",
          "UMLS:C1301363",
          "icd11.foundation:783045723"
        ],
        "synonyms": [
          "BPDCN",
          "CD4+/CD56+ hematodermic neoplasm",
          "agranular CD4+ CD56+ hematodermic neoplasm/tumor",
          "agranular CD4+ natural Killer cell leukaemia",
          "agranular CD4+ natural Killer cell leukemia",
          "blastic NK-cell lymphoma",
          "blastic natural Killer leukemia/lymphoma",
          "blastic plasmacytoid Dendritic cell neoplasm",
          "blastic plasmacytoid dendritic cell neoplasm",
          "early plasmacytoid Dendritic cell leukemia/lymphoma",
          "lymphoblastoid variant of NK-cell lymphoma",
          "monomorphic NK-cell lymphoma",
          "primary cutaneous CD4+/CD56+ hematolymphoid neoplasm",
          "blastic plasmacytoid dendritic cell"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An aggressive immature hematologic neoplasm formerly known as blastic NK cell lymphoma, composed of cells with a lymphoblast-like morphology. Recent evidence suggests derivation from a plasmacytoid monocyte. Patients present with cutaneous tumors and bone marrow involvement."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019467"
    },
    {
      "id": 20495,
      "label": "eyelid cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4353,
        4907,
        19757
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:173.1",
          "MEDGEN:501131",
          "NCIT:C6786",
          "Orphanet:98584",
          "SCTID:231829006",
          "SCTID:423425006",
          "UMLS:C1828015"
        ],
        "synonyms": [
          "cancer of eyelid",
          "cancer of skin of eyelid",
          "eyelid cancer",
          "malignant eyelid neoplasm",
          "malignant eyelid tumor",
          "malignant eyelid tumour",
          "malignant neoplasm of eyelid",
          "malignant neoplasm of skin of eyelid",
          "malignant neoplasm of the eyelid",
          "malignant skin of eyelid neoplasm",
          "malignant tumor of eyelid",
          "malignant tumor of palpebral epidermis",
          "malignant tumour of the eyelid",
          "skin of eyelid cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A cancer that involves the eyelid."
      },
      "child_count": 6,
      "reference_id": "MONDO:0021313"
    },
    {
      "id": 22966,
      "label": "sebaceous gland cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4907,
        8389
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:235134",
          "NCIT:C8409",
          "UMLS:C1382026"
        ],
        "synonyms": [
          "cancer of sebaceous gland",
          "malignant neoplasm of sebaceous gland",
          "malignant neoplasm of the sebaceous gland",
          "malignant sebaceous gland neoplasm",
          "malignant sebaceous gland tumor",
          "malignant sebaceous gland tumour",
          "malignant sebaceous neoplasm",
          "malignant sebaceous tumor",
          "malignant sebaceous tumour",
          "malignant tumor of sebaceous gland",
          "malignant tumor of the sebaceous gland",
          "malignant tumour of sebaceous gland",
          "malignant tumour of the sebaceous gland"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A cancer that involves the sebaceous gland."
      },
      "child_count": 2,
      "reference_id": "MONDO:0037735"
    }
  ],
  "roots": [
    {
      "id": 3053,
      "label": "integumentary system cancer"
    },
    {
      "id": 4599,
      "label": "skin neoplasm"
    }
  ]
}