{
  "id": 4927,
  "label": "malignant ovarian Brenner tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002920",
  "properties": {
    "xrefs": [
      "DOID:4217",
      "GARD:0023301",
      "ICDO:9000/3",
      "MEDGEN:90793",
      "NCIT:C4270",
      "UMLS:C0334495"
    ],
    "synonyms": [
      "malignant Brenner tumor of ovary",
      "malignant Brenner tumor of the ovary",
      "malignant Brenner tumour of ovary",
      "malignant Brenner tumour of the ovary",
      "malignant ovarian Brenner tumor",
      "ovarian Brenner tumor, malignant"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A malignant neoplasm that arises from the ovary and is characterized by the presence of an invasive malignant transitional cell component and nests of benign transitional cells in a fibrotic stroma. When the neoplasm is confined to the ovary, the prognosis is good."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4468,
      "label": "ovarian Brenner tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4347,
        21291
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2636",
          "GARD:0009397",
          "MEDGEN:1716777",
          "NCIT:C3872",
          "SCTID:254859006",
          "UMLS:C5234884"
        ],
        "synonyms": [
          "Brenner tumor",
          "Brenner tumour",
          "Brenner neoplasm of ovary",
          "Brenner neoplasm of the ovary",
          "Brenner tumor of ovary",
          "Brenner tumor of the ovary",
          "Brenner tumour of ovary",
          "Brenner tumour of the ovary",
          "ovarian Brenner neoplasm",
          "ovarian Brenner tumor",
          "ovary Brenner tumor",
          "ovary Brenner tumour",
          "benign ovarian Brenner tumor",
          "benign ovarian Brenner tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign, borderline, or malignant transitional cell neoplasm arising from the ovary. It constitutes between 1% and 2% of all ovarian neoplasms. The average age at presentation is about 50 years. Grossly it is usually unilateral, firm and white or yellowish. Microscopically it consists of solid and cystic nests of epithelial cells resembling transitional epithelium surrounded by an abundant stromal component of dense, fibroblastic nature."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002370"
    },
    {
      "id": 18447,
      "label": "malignant epithelial tumor of ovary",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4347,
        6734,
        9481
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2151",
          "GARD:0009362",
          "MEDGEN:577291",
          "MESH:C538090",
          "NCIT:C40026",
          "Orphanet:398934",
          "SCTID:254849005",
          "UMLS:C0346161"
        ],
        "synonyms": [
          "epithelial cancer of ovary",
          "malignant ovarian epithelial tumor",
          "malignant ovarian epithelial tumour",
          "malignant ovarian surface epithelial-stromal neoplasm",
          "malignant ovarian surface epithelial-stromal tumor",
          "malignant ovarian surface epithelial-stromal tumour",
          "ovarian epithelial cancer",
          "ovarian epithelial tumor, malignant",
          "ovarian malignant epithelial tumor",
          "ovarian malignant epithelial tumour",
          "ovarian stromal cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An invasive malignant tumor that originates from the surface epithelium of the ovary. It is composed of malignant epithelial cells and stroma. Representative examples include serous adenocarcinoma, mucinous adenocarcinoma, endometrioid adenocarcinoma, clear cell adenocarcinoma, and malignant Brenner tumor."
      },
      "child_count": 18,
      "reference_id": "MONDO:0018364"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4468,
      "label": "ovarian Brenner tumor"
    },
    {
      "id": 18447,
      "label": "malignant epithelial tumor of ovary"
    }
  ]
}