{
  "id": 4933,
  "label": "spindle cell sarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002927",
  "properties": {
    "xrefs": [
      "DOID:4235",
      "ICDO:8801/3",
      "MEDGEN:64477",
      "NCIT:C27005",
      "UMLS:C0205945"
    ],
    "synonyms": [
      "spindle cell sarcoma"
    ],
    "definition": "A malignant mesenchymal neoplasm composed of spindle-shaped cells. This is a morphologic term which can be applied to a wide range of sarcomas."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 6816,
      "label": "sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1115",
          "EFO:0000691",
          "ICD9:171",
          "ICD9:171.0",
          "ICD9:171.2",
          "ICD9:171.3",
          "ICD9:171.4",
          "ICD9:171.5",
          "ICD9:171.6",
          "ICD9:171.7",
          "ICD9:171.8",
          "ICD9:171.9",
          "ICDO:8800/3",
          "MEDGEN:224714",
          "MESH:D012509",
          "NCIT:C9118",
          "SCTID:424413001",
          "UMLS:C1261473"
        ],
        "synonyms": [
          "mesenchymal tumor, malignant",
          "sarcoma",
          "sarcoma of soft tissue and bone",
          "sarcoma of the soft tissue and bone",
          "sarcoma, malignant",
          "tumor of soft tissue and skeleton",
          "tumour of soft tissue and skeleton"
        ],
        "definition": "A usually aggressive malignant neoplasm of the soft tissue or bone. It arises from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The prognosis depends largely on the degree of differentiation (grade) of the neoplasm. Representative subtypes are liposarcoma, leiomyosarcoma, osteosarcoma, and chondrosarcoma."
      },
      "child_count": 22,
      "reference_id": "MONDO:0005089"
    },
    {
      "id": 20076,
      "label": "malignant spindle cell neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        20077
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:90746",
          "NCIT:C27091",
          "UMLS:C0334230"
        ],
        "synonyms": [
          "malignant spindle cell neoplasm",
          "malignant spindle cell tumor",
          "malignant spindle cell tumour",
          "spindle cell cancer"
        ],
        "definition": "A malignant neoplasm characterized by the presence of atypical spindle cells."
      },
      "child_count": 8,
      "reference_id": "MONDO:0020663"
    }
  ],
  "children": [
    {
      "id": 4642,
      "label": "spindle cell rhabdomyosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4933,
        6928
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3260",
          "GARD:0023175",
          "ICD9:171.9",
          "ICDO:8912/3",
          "MEDGEN:224766",
          "NCIT:C6519",
          "ONCOTREE:SCRMS",
          "SCTID:404055006",
          "UMLS:C1266134"
        ],
        "synonyms": [
          "spindle cell rhabdomyosarcoma (morphologic abnormality)",
          "SCRMS"
        ],
        "definition": "An uncommon variant of rhabdomyosarcoma characterized by the presence of whorls of spindle cells forming a storiform pattern. In children it usually arises in the paratesticular region. In adults it usually arises from the deep soft tissues in the head and neck."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002581"
    },
    {
      "id": 5388,
      "label": "spindle cell synovial sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4933,
        6796
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5487",
          "GARD:0023513",
          "ICDO:9041/3",
          "MEDGEN:90795",
          "NCIT:C4277",
          "UMLS:C0334505"
        ],
        "synonyms": [
          "synovial sarcoma with spindle cell components"
        ],
        "definition": "A synovial sarcoma characterized by the presence of a spindle cell component only."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003466"
    },
    {
      "id": 5491,
      "label": "spindle cell liposarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4933,
        6830
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5705",
          "GARD:0023580",
          "ICD9:171.9",
          "MEDGEN:266156",
          "NCIT:C27489",
          "SCTID:404073009",
          "UMLS:C1275275"
        ],
        "synonyms": [
          "spindle cell liposarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A morphologic variant of well differentiated liposarcoma characterized by the presence of bland spindle cells and lipoblasts within a myxoid or fibrous stroma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003596"
    },
    {
      "id": 7802,
      "label": "intimal sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4933,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000305",
          "GARD:0024348",
          "MEDGEN:317791",
          "NCIT:C53677",
          "ONCOTREE:INTS",
          "UMLS:C1708550"
        ],
        "synonyms": [
          "INTS"
        ],
        "definition": "A malignant neoplasm arising from the large blood vessels. It is characterized by the presence of tumor cells that grow within the lumen of the blood vessels. The intraluminal tumor growth may result in vascular obstruction and spread of tumor emboli to peripheral organs. The prognosis is usually poor."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006255"
    }
  ],
  "roots": [
    {
      "id": 6816,
      "label": "sarcoma"
    },
    {
      "id": 20076,
      "label": "malignant spindle cell neoplasm"
    }
  ]
}