{
  "id": 4936,
  "label": "kidney sarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002930",
  "properties": {
    "xrefs": [
      "DOID:4242",
      "GARD:0023305",
      "ICD9:189.0",
      "MEDGEN:87548",
      "NCIT:C4525",
      "SCTID:254918001",
      "UMLS:C0346251"
    ],
    "synonyms": [
      "kidney sarcoma",
      "renal sarcoma",
      "sarcoma of kidney",
      "sarcoma of the kidney"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "A sarcoma involving a kidney."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 4465,
      "label": "kidney cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7836,
        20396
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:263",
          "ICD9:189.0",
          "MEDGEN:149263",
          "MESH:D007680",
          "NCIT:C7548",
          "SCTID:363518003",
          "UMLS:C0740457"
        ],
        "synonyms": [
          "cancer of kidney",
          "kidney cancer",
          "malignant kidney neoplasm",
          "malignant kidney tumor",
          "malignant kidney tumour",
          "malignant neoplasm of kidney",
          "malignant neoplasm of the kidney",
          "malignant renal neoplasm",
          "malignant renal tumor",
          "malignant renal tumour",
          "malignant tumor of kidney",
          "malignant tumor of the kidney",
          "malignant tumour of the kidney"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Primary or metastatic malignant neoplasm involving the kidney."
      },
      "child_count": 16,
      "reference_id": "MONDO:0002367"
    },
    {
      "id": 18239,
      "label": "soft tissue sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6816,
        21548
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070663",
          "EFO:1001968",
          "GARD:0004898",
          "MEDGEN:1642116",
          "NCIT:C9306",
          "NORD:1953",
          "Orphanet:3394",
          "SCTID:424952003",
          "UMLS:C4551687"
        ],
        "synonyms": [
          "malignant soft tissue tumor",
          "malignant soft tissue tumour",
          "connective tissue sarcoma",
          "malignant mesenchymal tumor",
          "malignant mesenchymal tumour",
          "non-Rhabdo. soft tissue sarcoma",
          "sarcoma of soft tissue",
          "sarcoma of the soft tissue",
          "soft part sarcoma",
          "soft tissue sarcoma"
        ],
        "definition": "A malignant neoplasm arising from muscle tissue, adipose tissue, blood vessels, fibrous tissue, or other supportive tissues excluding the bones."
      },
      "child_count": 92,
      "reference_id": "MONDO:0018078"
    }
  ],
  "children": [
    {
      "id": 4766,
      "label": "rhabdoid tumor of the kidney",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4765,
        4936
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3674",
          "EFO:1000512",
          "GARD:0023224",
          "MEDGEN:208930",
          "NCIT:C8715",
          "UMLS:C0854917"
        ],
        "synonyms": [
          "MRTK",
          "kidney rhabdoid tumor",
          "kidney rhabdoid tumour",
          "malignant rhabdoid tumor of kidney",
          "malignant rhabdoid tumor of the kidney",
          "malignant rhabdoid tumour of kidney",
          "malignant rhabdoid tumour of the kidney",
          "renal rhabdoid neoplasm",
          "renal rhabdoid tumor",
          "renal rhabdoid tumour",
          "rhabdoid neoplasm of kidney",
          "rhabdoid neoplasm of the kidney",
          "rhabdoid tumor of kidney",
          "rhabdoid tumor of the kidney",
          "rhabdoid tumor of the kidney (RTK)",
          "rhabdoid tumour of kidney",
          "rhabdoid tumour of the kidney (RTK)",
          "kidney rhabdoid cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A rhabdoid tumor that arises from the kidney. It occurs in children and it is associated with abnormalities of chromosome 22. It is characterized by the presence of cells with a large eccentric nucleus, prominent nucleolus, and abundant cytoplasm. The prognosis is poor."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002729"
    },
    {
      "id": 5308,
      "label": "kidney leiomyosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4936,
        6788
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5287",
          "GARD:0023486",
          "MEDGEN:235545",
          "NCIT:C6183",
          "UMLS:C1335743"
        ],
        "synonyms": [
          "kidney leiomyosarcoma",
          "leiomyosarcoma of kidney",
          "leiomyosarcoma of the kidney",
          "renal leiomyosarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "An aggressive malignant smooth muscle neoplasm, arising from the kidney. It is characterized by a proliferation of neoplastic spindle cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003373"
    },
    {
      "id": 5486,
      "label": "kidney liposarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4936,
        6790
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5699",
          "GARD:0023575",
          "MEDGEN:235546",
          "NCIT:C6185",
          "UMLS:C1335745"
        ],
        "synonyms": [
          "kidney liposarcoma",
          "liposarcoma of kidney",
          "liposarcoma of the kidney",
          "renal liposarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A rare malignant adipose tissue neoplasm of the fat cells surrounding the kidney, usually of the well-differentiated or myxoid type. It may be associated with tuberous sclerosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003591"
    },
    {
      "id": 5601,
      "label": "kidney fibrosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4936,
        6886
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5982",
          "GARD:0023631",
          "MEDGEN:116050",
          "NCIT:C7726",
          "UMLS:C0238208"
        ],
        "synonyms": [
          "fibrosarcoma of kidney",
          "fibrosarcoma of the kidney",
          "kidney fibrosarcoma",
          "kidney fibrosarcoma (disease)",
          "renal fibrosarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A usually aggressive malignant neoplasm arising from the kidney. It is characterized by the presence of spindle-shaped fibroblasts and collagenous stroma formation in a herringbone growth pattern."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003720"
    },
    {
      "id": 5602,
      "label": "kidney osteogenic sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4672,
        4936
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5983",
          "GARD:0023632",
          "MEDGEN:235547",
          "NCIT:C6181",
          "UMLS:C1335747"
        ],
        "synonyms": [
          "kidney extraskeletal osteosarcoma",
          "kidney osteogenic sarcoma",
          "kidney osteosarcoma",
          "kidney osteosarcoma (disease)",
          "osteogenic sarcoma of kidney",
          "osteogenic sarcoma of the kidney",
          "osteosarcoma of kidney",
          "osteosarcoma of the kidney",
          "renal extraskeletal osteosarcoma",
          "renal osteogenic sarcoma",
          "renal osteosarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "An osteosarcoma arising from the kidney."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003721"
    },
    {
      "id": 6744,
      "label": "clear cell sarcoma of kidney",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4932,
        4936
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4880",
          "EFO:0000350",
          "GARD:0021905",
          "ICDO:8964/3",
          "MEDGEN:90791",
          "NANDO:2200044",
          "NCIT:C4264",
          "ONCOTREE:CCSK",
          "Orphanet:457246",
          "UMLS:C0334488"
        ],
        "synonyms": [
          "CCSK",
          "childhood clear cell sarcoma of the kidney",
          "childhood kidney clear cell sarcoma",
          "childhood renal clear cell sarcoma",
          "clear cell sarcoma - kidney",
          "clear cell sarcoma of kidney",
          "clear cell sarcoma of the kidney",
          "kidney clear cell sarcoma",
          "paediatric kidney clear cell sarcoma",
          "paediatric renal clear cell sarcoma",
          "pediatric kidney clear cell sarcoma",
          "pediatric renal clear cell sarcoma",
          "renal clear cell sarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A rare pediatric sarcoma affecting the kidney. It is characterized by the presence of epithelioid or spindle cells forming cords or nests, separated by fibrovascular septa. It is associated with internal tandem duplications in the BCOR gene. It metastasizes to lung, bone, brain and soft tissue."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005006"
    },
    {
      "id": 25847,
      "label": "anaplastic sarcoma of the kidney",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4936
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081418",
          "GARD:0026951",
          "MEDGEN:1661979",
          "NCIT:C154496",
          "UMLS:C4722276"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A kidney sarcoma that is characterized by a proliferation of anaplastic spindle cells with bizarre, pleomorphic nuclei and atypical mitotic figures."
      },
      "child_count": 0,
      "reference_id": "MONDO:0958165"
    }
  ],
  "roots": [
    {
      "id": 4465,
      "label": "kidney cancer"
    },
    {
      "id": 18239,
      "label": "soft tissue sarcoma"
    }
  ]
}