{
  "id": 4985,
  "label": "peripheral primitive neuroectodermal tumor of soft tissues",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002982",
  "properties": {
    "xrefs": [
      "DOID:4389",
      "GARD:0023313",
      "MEDGEN:205115",
      "NCIT:C27471",
      "UMLS:C1112437"
    ],
    "synonyms": [
      "peripheral neuroectodermal tumor of soft tissues",
      "peripheral neuroectodermal tumor of the soft tissues",
      "peripheral neuroectodermal tumour of soft tissues",
      "peripheral neuroectodermal tumour of the soft tissues",
      "peripheral neuroepithelioma of soft tissues",
      "peripheral neuroepithelioma of the soft tissues",
      "peripheral primitive neuroectodermal tumor of soft tissues",
      "soft tissue peripheral neuroepithelioma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A small round cell tumor with neural differentiation arising from the soft tissues."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 18390,
      "label": "peripheral primitive neuroectodermal tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7121,
        20283,
        20329
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017601",
          "ICDO:9364/3",
          "MEDGEN:151926",
          "NANDO:2200054",
          "NANDO:2200055",
          "NCIT:C9341",
          "Orphanet:370348",
          "UMLS:C0684337"
        ],
        "synonyms": [
          "PPNET",
          "pPNET",
          "peripheral PNET",
          "peripheral neuroectodermal neoplasm",
          "peripheral neuroectodermal tumor",
          "peripheral neuroectodermal tumour",
          "peripheral neuroepithelioma",
          "peripheral primitive neuroectodermal neoplasm",
          "peripheral primitive neuroectodermal tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A small round cell tumor with neural differentiation arising from the soft tissues or bone."
      },
      "child_count": 9,
      "reference_id": "MONDO:0018271"
    },
    {
      "id": 20284,
      "label": "extraskeletal Ewing sarcoma/peripheral primitive neuroectodermal tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20283
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4985",
          "EFO:1000250",
          "MEDGEN:232170",
          "NCIT:C27293",
          "UMLS:C1333514"
        ],
        "synonyms": [
          "extraosseous Ewing sarcoma/peripheral primitive neuroectodermal tumor",
          "extraosseous Ewing sarcoma/peripheral primitive neuroectodermal tumour",
          "extraosseous Ewing's sarcoma/peripheral primitive neuroectodermal tumor",
          "extraosseous Ewing's sarcoma/peripheral primitive neuroectodermal tumour",
          "extraosseous Ewings sarcoma-primitive neuroepithelial tumor",
          "extraskeletal Ewing sarcoma/peripheral primitive neuroectodermal tumor",
          "extraosseous Ewing's tumor",
          "extraosseous Ewing's tumour"
        ],
        "definition": "A spectrum of malignant tumors arising from the soft tissues, characterized morphologically by the presence of small round cells. Ewing sarcoma and peripheral primitive neuroectodermal tumor represent the ends of a spectrum, with Ewing sarcoma lacking evidence of neural differentiation and the markers that characterize the peripheral primitive neuroectodermal tumor. Ewing sarcoma and peripheral primitive neuroectodermal tumor may share cytogenetic abnormalities, proto-oncogene expression, cell culture and immunohistochemical abnormalities. Pain and the presence of a mass are the most common clinical symptoms."
      },
      "child_count": 2,
      "reference_id": "MONDO:0021039"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 18390,
      "label": "peripheral primitive neuroectodermal tumor"
    },
    {
      "id": 20284,
      "label": "extraskeletal Ewing sarcoma/peripheral primitive neuroectodermal tumor"
    }
  ]
}