{
  "id": 4997,
  "label": "skull base meningioma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002998",
  "properties": {
    "xrefs": [
      "DOID:4437",
      "GARD:0023319",
      "MEDGEN:233449",
      "NCIT:C5272",
      "UMLS:C1335976"
    ],
    "synonyms": [
      "basicranium meningioma (disease)",
      "meningioma (disease) of basicranium",
      "meningioma of the skull base",
      "skull base meningioma",
      "meningioma of skull base"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A meningioma that arises from the skull base."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 10,
  "parents": [
    {
      "id": 4813,
      "label": "skull base neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21561
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3842",
          "GARD:0023244",
          "MEDGEN:138208",
          "MESH:D019292",
          "NCIT:C4676",
          "UMLS:C0376527"
        ],
        "synonyms": [
          "basicranium neoplasm",
          "basicranium neoplasm (disease)",
          "basicranium tumor",
          "basicranium tumour",
          "neoplasm of basicranium",
          "neoplasm of skull base",
          "neoplasm of the skull base",
          "skull base neoplasm",
          "skull base tumor",
          "skull base tumour",
          "tumor of basicranium",
          "tumor of skull base",
          "tumor of the skull base",
          "tumour of basicranium",
          "tumour of skull base",
          "tumour of the skull base",
          "tumours of skull base",
          "skull base cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the skull base."
      },
      "child_count": 5,
      "reference_id": "MONDO:0002785"
    },
    {
      "id": 17113,
      "label": "meningioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17192
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3565",
          "GARD:0007015",
          "HP:0002858",
          "ICDO:9530/0",
          "MEDGEN:7532",
          "MESH:D008579",
          "MedDRA:10027191",
          "NANDO:2200094",
          "NCIT:C3230",
          "NORD:1434",
          "ONCOTREE:MNG",
          "Orphanet:2495",
          "SCTID:302820008",
          "UMLS:C0025286",
          "icd11.foundation:672106711"
        ],
        "synonyms": [
          "meningioma",
          "meningioma (disease)",
          "intracranial meningioma",
          "meningeal neoplasm",
          "meningothelial cell tumor",
          "meningothelial cell tumour",
          "primary meningeal tumor",
          "primary meningeal tumour",
          "supratentorial meningioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A generally slow growing tumor attached to the dura mater. It is composed of neoplastic meningothelial (arachnoidal) cells. It typically occurs in adults, often women and it has a wide range of histopathological appearances. Of the various subtypes, meningothelial, fibrous and transitional meningiomas are the most common. Most meningiomas are WHO grade I tumors, and some are WHO grade II or III tumors. Most subtypes share a common clinical behavior, although some subtypes are more likely to recur and follow a more aggressive clinical course. (Adapted from WHO)"
      },
      "child_count": 37,
      "reference_id": "MONDO:0016642"
    }
  ],
  "children": [
    {
      "id": 4995,
      "label": "cavernous sinus meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4997,
        6420,
        20321,
        21452,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4435",
          "GARD:0023317",
          "MEDGEN:232034",
          "NCIT:C5268",
          "UMLS:C1332865"
        ],
        "synonyms": [
          "cavernous sinus meningioma (disease)",
          "meningioma (disease) of cavernous sinus",
          "meningioma of cavernous sinus",
          "meningioma of the cavernous sinus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that affects the cavernous sinus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002996"
    },
    {
      "id": 5090,
      "label": "foramen magnum meningioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4997
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4708",
          "GARD:0023369",
          "MEDGEN:232512",
          "NCIT:C5280",
          "UMLS:C1333630"
        ],
        "synonyms": [
          "foramen magnum meningioma (disease)",
          "meningioma (disease) of foramen magnum",
          "meningioma of Foramen magnum",
          "meningioma of the Foramen magnum"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that affects the foramen magnum."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003109"
    },
    {
      "id": 5770,
      "label": "clivus meningioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4926,
        4997
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6517",
          "GARD:0023727",
          "MEDGEN:272489",
          "NCIT:C5289",
          "UMLS:C1333073"
        ],
        "synonyms": [
          "clivus of occipital bone meningioma (disease)",
          "meningioma (disease) of clivus of occipital bone",
          "meningioma of clivus",
          "meningioma of the clivus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that affects the clivus."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003908"
    },
    {
      "id": 5929,
      "label": "multiple skull base meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4997
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7054",
          "GARD:0023817",
          "MEDGEN:233723",
          "NCIT:C5279",
          "UMLS:C1334829"
        ],
        "synonyms": [
          "multiple skull base meningiomas"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Multiple meningiomas that affect the skull base."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004094"
    },
    {
      "id": 5942,
      "label": "diaphragma sellae meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4759,
        4997
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7103",
          "GARD:0023829",
          "MEDGEN:234200",
          "NCIT:C5283",
          "UMLS:C1333283"
        ],
        "synonyms": [
          "diaphragm sellae meningioma",
          "diaphragma sellae meningioma (disease)",
          "meningioma (disease) of diaphragma sellae",
          "meningioma of Diaphragma sellae",
          "meningioma of diaphragm sellae",
          "meningioma of the Diaphragma sellae",
          "meningioma of the diaphragm sellae"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that affects the diaphragma sellae."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004108"
    },
    {
      "id": 6128,
      "label": "suprasellar meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4997,
        21213
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7634",
          "GARD:0023926",
          "MEDGEN:234911",
          "NCIT:C6776",
          "UMLS:C1336535"
        ],
        "synonyms": [
          "meningioma (disease) of sella turcica",
          "sella turcica meningioma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that affects the suprasellar region."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004312"
    },
    {
      "id": 6180,
      "label": "petroclival meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4997
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7818",
          "GARD:0023961",
          "MEDGEN:277511",
          "NCIT:C5278",
          "UMLS:C1335395"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that affects the petroclival region."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004367"
    },
    {
      "id": 6181,
      "label": "sphenoorbital meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4997
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7819",
          "GARD:0023962",
          "MEDGEN:233458",
          "NCIT:C5285",
          "UMLS:C1336040"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that affects the sphenoorbital region."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004368"
    },
    {
      "id": 6183,
      "label": "sphenocavernous meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4997
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7820",
          "GARD:0023963",
          "MEDGEN:234801",
          "NCIT:C5313",
          "UMLS:C1336036"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that affects the sphenocavernous region."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004370"
    },
    {
      "id": 6253,
      "label": "pituitary stalk meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4996,
        4997,
        5202
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8058",
          "GARD:0024010",
          "MEDGEN:233858",
          "NCIT:C5311",
          "UMLS:C1335422"
        ],
        "synonyms": [
          "meningioma (disease) of pituitary stalk",
          "meningioma of pituitary stalk",
          "meningioma of the pituitary stalk",
          "pituitary stalk meningioma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A meningioma that affects the pituitary stalk."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004447"
    }
  ],
  "roots": [
    {
      "id": 4813,
      "label": "skull base neoplasm"
    },
    {
      "id": 17113,
      "label": "meningioma"
    }
  ]
}