{
  "id": 5000,
  "label": "seminoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003001",
  "properties": {
    "xrefs": [
      "DOID:4440",
      "GARD:0023322",
      "ICD9:186.9",
      "ICDO:9061/3",
      "MEDGEN:11371",
      "MESH:D018239",
      "NCIT:C9309",
      "ONCOTREE:SEM",
      "SCTID:443675005",
      "UMLS:C0036631"
    ],
    "synonyms": [
      "seminoma",
      "seminoma, malignant",
      "seminoma, pure"
    ],
    "definition": "A radiosensitive malignant germ cell tumor found in the testis (especially undescended), and extragonadal sites (anterior mediastinum and pineal gland). It is characterized by the presence of uniform cells with clear or dense cytoplasm which contains glycogen, and by a large nucleus which contains one or more nucleoli. The neoplastic germ cells form aggregates separated by fibrous septa. The fibrous septa contain chronic inflammatory cells, mainly lymphocytes."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 7832,
      "label": "malignant germ cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        6773
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000352",
          "GARD:0003360",
          "MEDGEN:890580",
          "NCIT:C4925",
          "SCTID:145831000119103",
          "UMLS:C4048549"
        ],
        "synonyms": [
          "cancer of germ cell",
          "germ cell cancer",
          "germ cell tumor, malignant",
          "malignant germ cell neoplasm",
          "malignant germ cell tumor",
          "malignant neoplasm of germ cell",
          "malignant neoplasm of the germ cell",
          "malignant tumor of germ cell",
          "malignant tumor of the germ cell",
          "malignant tumour of germ cell",
          "malignant tumour of the germ cell"
        ],
        "definition": "A gonadal or extragonadal malignant neoplasm that arises from germ cells. Representative examples include embryonal carcinoma, yolk sac tumor, and seminoma."
      },
      "child_count": 26,
      "reference_id": "MONDO:0006290"
    },
    {
      "id": 20017,
      "label": "germinomatous germ cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6773
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025174",
          "MEDGEN:888719",
          "NCIT:C121618",
          "UMLS:C4054897"
        ],
        "synonyms": [
          "germinomatous germ cell tumor"
        ],
        "definition": "A term that refers to germinoma, seminoma, or dysgerminoma."
      },
      "child_count": 2,
      "reference_id": "MONDO:0020580"
    }
  ],
  "children": [
    {
      "id": 5553,
      "label": "extragonadal seminoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5000,
        5094
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5838",
          "GARD:0023613",
          "MEDGEN:234243",
          "NCIT:C7327",
          "UMLS:C1333502"
        ],
        "synonyms": [
          "extragonadal primary seminoma",
          "extragonadal seminoma",
          "primary extragonadal seminoma"
        ]
      },
      "child_count": 2,
      "reference_id": "MONDO:0003668"
    },
    {
      "id": 5554,
      "label": "testicular seminoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4887,
        5000,
        5424
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5842",
          "EFO:0003101",
          "GARD:0004792",
          "HP:0100617",
          "ICD9:186.9",
          "MEDGEN:1790467",
          "NCIT:C7328",
          "Orphanet:842",
          "SCTID:255107005",
          "UMLS:C5551428"
        ],
        "synonyms": [
          "seminoma of testis",
          "seminoma of the testis",
          "seminomatous germ cell tumor of testis",
          "seminomatous germ cell tumour of testis",
          "testicular seminoma",
          "testicular seminoma (disease)",
          "testicular seminoma Pure",
          "testicular seminomatous germ cell tumor",
          "testicular seminomatous germ cell tumour",
          "testis seminoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A malignant germ cell tumor arising from the testis. It is believed that it is derived from the sexually undifferentiated embryonic gonad. Treatment with radiotherapy is highly successful when the tumor is diagnosed in localized stages, which represents the majority of presentations of seminoma."
      },
      "child_count": 12,
      "reference_id": "MONDO:0003669"
    }
  ],
  "roots": [
    {
      "id": 7832,
      "label": "malignant germ cell tumor"
    },
    {
      "id": 20017,
      "label": "germinomatous germ cell tumor"
    }
  ]
}