{
  "id": 5029,
  "label": "mucoepidermoid carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003036",
  "properties": {
    "xrefs": [
      "DOID:163",
      "DOID:4531",
      "GARD:0010671",
      "ICDO:8430/1",
      "ICDO:8430/3",
      "MEDGEN:61662",
      "MESH:D018277",
      "MESH:D018298",
      "NCIT:C3772",
      "ONCOTREE:MUCC",
      "UMLS:C0206694",
      "icd11.foundation:287052516"
    ],
    "synonyms": [
      "MEC",
      "mucoepidermoid carcinoma",
      "mucoepidermoid carcinoma (morphologic abnormality)",
      "mucoepidermoid tumor",
      "mucoepidermoid tumour",
      "MUCC",
      "mucoepidermoid tumors",
      "mucoepidermoid tumours",
      "tumor, mucoepidermoid",
      "tumors, mucoepidermoid"
    ],
    "definition": "A carcinoma morphologically characterized the presence of cuboidal mucous cells, goblet-like mucous cells, squamoid cells, cystic changes, and a fibrotic stromal formation. It can occur in several anatomic sites, including parotid gland, oral cavity, paranasal sinus, skin, breast, lung, larynx, and lacrimal ducts. It is classified as low or high grade."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 12,
  "parents": [
    {
      "id": 6700,
      "label": "mucinous adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712,
        20031
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3030",
          "EFO:0000197",
          "ICDO:8480/3",
          "MEDGEN:2844",
          "MESH:D002288",
          "NCIT:C26712",
          "ONCOTREE:CEMU",
          "UMLS:C0007130",
          "icd11.foundation:529352875"
        ],
        "synonyms": [
          "adenocarcinoma, mucinous, malignant",
          "colloid adenocarcinoma",
          "colloid carcinoma",
          "gelatinous adenocarcinoma",
          "gelatinous carcinoma",
          "mucin-producing adenocarcinoma (morphologic abnormality)",
          "mucinous adenocarcinoma",
          "mucinous carcinoma",
          "mucinuos carcinoma",
          "mucoid adenocarcinoma",
          "mucoid carcinoma",
          "mucous adenocarcinoma",
          "mucous carcinoma",
          "CEMU"
        ],
        "definition": "An invasive adenocarcinoma composed of malignant glandular cells which contain intracytoplasmic mucin. Often, the infiltrating glandular structures are associated with mucoid stromal formation. It may arise from the large and small intestine, appendix, stomach, lung, ovary, breast, corpus uteri, cervix, vagina, and salivary gland."
      },
      "child_count": 34,
      "reference_id": "MONDO:0004957"
    },
    {
      "id": 8180,
      "label": "cystic, mucinous, and serous neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000889",
          "MEDGEN:61678",
          "MESH:D018297",
          "UMLS:C0206767"
        ],
        "definition": "Neoplasms containing cyst-like formations or producing mucin or serum."
      },
      "child_count": 1,
      "reference_id": "MONDO:0006720"
    }
  ],
  "children": [
    {
      "id": 2979,
      "label": "trachea mucoepidermoid carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5029,
        5144
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050919",
          "GARD:0022793",
          "MEDGEN:835970",
          "SCTID:707379000",
          "UMLS:C3873401"
        ],
        "synonyms": [
          "trachea mucoepidermoid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A mucoepidermoid carcinoma that involves the trachea."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000534"
    },
    {
      "id": 5072,
      "label": "thymic mucoepidermoid carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5029,
        5165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4678",
          "GARD:0023360",
          "MEDGEN:277383",
          "NCIT:C6457",
          "UMLS:C1334814"
        ],
        "synonyms": [
          "Thymus mucoepidermoid carcinoma",
          "mucoepidermoid carcinoma of Thymus",
          "mucoepidermoid carcinoma of the Thymus",
          "thymic mucoepidermoid carcinoma",
          "thymus mucoepidermoid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A rare primary thymic carcinoma, characterized by the presence of squamous cells, intermediate type cells, and mucus-producing cells. Published information on clinical course is limited to single-case reports."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003086"
    },
    {
      "id": 5073,
      "label": "mucoepidermoid breast carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5029,
        6729,
        7803
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4679",
          "GARD:0023361",
          "MEDGEN:233721",
          "NCIT:C5166",
          "UMLS:C1334813"
        ],
        "synonyms": [
          "breast mucoepidermoid carcinoma",
          "mucoepidermoid breast carcinoma",
          "mucoepidermoid carcinoma of breast",
          "mucoepidermoid carcinoma of the breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A carcinoma of the breast characterized by pools of mucin and islands of malignant squamous cells. Mucoepidermoid carcinomas of the breast are extremely rare."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003087"
    },
    {
      "id": 5075,
      "label": "extrahepatic bile duct mucoepidermoid carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4775,
        5029
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4681",
          "GARD:0023362",
          "MEDGEN:272368",
          "NCIT:C5862",
          "UMLS:C1332552"
        ],
        "synonyms": [
          "bile duct mucoepidermoid carcinoma",
          "extrahepatic bile duct mucoepidermoid carcinoma",
          "mucoepidermoid carcinoma of bile duct",
          "mucoepidermoid carcinoma of the bile duct"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A mucoepidermoid carcinoma that arises from the extrahepatic bile ducts."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003089"
    },
    {
      "id": 5077,
      "label": "cutaneous mucoepidermoid carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4707,
        5029
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4683",
          "GARD:0023364",
          "MEDGEN:91072",
          "NCIT:C4472",
          "SCTID:254713002",
          "UMLS:C0346019"
        ],
        "synonyms": [
          "zone of skin mucoepidermoid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A mucoepidermoid carcinoma that involves the zone of skin."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003091"
    },
    {
      "id": 5078,
      "label": "lacrimal gland mucoepidermoid carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4555,
        5029
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4685",
          "GARD:0023365",
          "MEDGEN:235248",
          "NCIT:C6091",
          "UMLS:C1334359"
        ],
        "synonyms": [
          "lacrimal gland mucoepidermoid carcinoma",
          "mucoepidermoid carcinoma of lacrimal gland",
          "mucoepidermoid carcinoma of the lacrimal gland"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "An extremely rare carcinoma that arises from the lacrimal gland. It is characterized by the presence of infiltrating nests of epidermoid cells and mucus producing cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003092"
    },
    {
      "id": 5079,
      "label": "mucoepidermoid esophageal carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5029,
        6762
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4686",
          "GARD:0023366",
          "MEDGEN:234232",
          "NCIT:C5343",
          "UMLS:C1333461"
        ],
        "synonyms": [
          "esophagus mucoepidermoid carcinoma",
          "mucoepidermoid carcinoma of the esophagus",
          "mucoepidermoid carcinoma of the oesophagus",
          "oesophagus mucoepidermoid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A rare carcinoma of the esophagus which contains squamous cells, mucus secreting cells, and cells of an intermediate type. (WHO)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0003093"
    },
    {
      "id": 5080,
      "label": "laryngeal mucoepidermoid carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4457,
        5029
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4688",
          "GARD:0023367",
          "MEDGEN:272792",
          "NCIT:C9463",
          "UMLS:C1334373"
        ],
        "synonyms": [
          "laryngeal mucoepidermoid carcinoma",
          "laryngeal throat mucoepidermoid cancer",
          "larynx mucoepidermoid carcinoma",
          "mucoepidermoid carcinoma of larynx",
          "mucoepidermoid carcinoma of the larynx"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A rare mucoepidermoid carcinoma of the larynx. It usually arises from the supraglottic area. Hoarseness and dysphagia are the presenting symptoms."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003095"
    },
    {
      "id": 7256,
      "label": "pulmonary mucoepidermoid carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5029,
        21771
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050932",
          "EFO:0006740",
          "GARD:0024212",
          "MEDGEN:310949",
          "NCIT:C45544",
          "ONCOTREE:LUMEC",
          "UMLS:C1708778"
        ],
        "synonyms": [
          "lung mucoepidermoid cancer",
          "lung mucoepidermoid carcinoma",
          "mucoepidermoid carcinoma of the lung"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A lung carcinoma characterized by the presence of malignant non-keratinizing squamoid cells, mucin-producing cells and intermediate type cells."
      },
      "child_count": 2,
      "reference_id": "MONDO:0005616"
    },
    {
      "id": 7964,
      "label": "thyroid gland mucoepidermoid carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5029,
        21537
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4687",
          "EFO:1000590",
          "GARD:0024420",
          "MEDGEN:270845",
          "NCIT:C38762",
          "UMLS:C1513721"
        ],
        "synonyms": [
          "mucoepidermoid thyroid carcinoma",
          "mucoepidermoid thyroid gland carcinoma",
          "thyroid gland mucoepidermoid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A primary, low grade carcinoma of the thyroid gland composed of groups of squamoid and mucous cells, surrounded by fibrous tissue. Prominent cystic structures may be present. The clinical course is usually indolent."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006463"
    },
    {
      "id": 23486,
      "label": "paranasal sinus mucoepidermoid carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2879,
        5029
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025925",
          "MEDGEN:235461",
          "NCIT:C6018",
          "UMLS:C1335340"
        ],
        "synonyms": [
          "accessory sinus mucoepidermoid carcinoma",
          "mucoepidermoid carcinoma of accessory sinus",
          "mucoepidermoid carcinoma of paranasal sinus",
          "mucoepidermoid carcinoma of the accessory sinus",
          "mucoepidermoid carcinoma of the paranasal sinus",
          "paranasal sinus mucoepidermoid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A rare carcinoma that arises from the paranasal sinus. It is characterized by the presence of epidermoid cells, mucus producing cells, and cells of intermediate type."
      },
      "child_count": 0,
      "reference_id": "MONDO:0044956"
    },
    {
      "id": 23487,
      "label": "oral cavity mucoepidermoid carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5029,
        23483
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025926",
          "MEDGEN:83629",
          "NCIT:C8177",
          "UMLS:C0280309"
        ],
        "synonyms": [
          "mucoepidermoid carcinoma of oral cavity",
          "mucoepidermoid carcinoma of the oral cavity",
          "oral cavity mucoepidermoid cancer",
          "oral cavity mucoepidermoid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A mucoepidermoid carcinoma arising from the minor salivary glands in the oral cavity. It is often asymptomatic and detected during a routine dental examination."
      },
      "child_count": 4,
      "reference_id": "MONDO:0044964"
    }
  ],
  "roots": [
    {
      "id": 6700,
      "label": "mucinous adenocarcinoma"
    },
    {
      "id": 8180,
      "label": "cystic, mucinous, and serous neoplasm"
    }
  ]
}