{
  "id": 5038,
  "label": "thymic large cell neuroendocrine carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003047",
  "properties": {
    "xrefs": [
      "DOID:4553",
      "GARD:0023344",
      "MEDGEN:235250",
      "NCIT:C6461",
      "UMLS:C1334364"
    ],
    "synonyms": [
      "large cell neuroendocrine carcinoma of Thymus",
      "large cell neuroendocrine carcinoma of the Thymus",
      "large cell neuroendocrine carcinoma of thymus",
      "thymic LCNEC",
      "thymic large cell neuroendocrine carcinoma",
      "thymus large cell carcinoma",
      "thymus large cell neuroendocrine carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "An aggressive, non-small cell, poorly differentiated thymic neuroendocrine carcinoma, characterized by the presence of a high mitotic rate and, almost always, necrosis."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6787,
      "label": "large cell neuroendocrine carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4255,
        6943
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050872",
          "EFO:0000563",
          "GARD:0024145",
          "ICDO:8013/3",
          "MEDGEN:220402",
          "NCIT:C6875",
          "ONCOTREE:LUNE",
          "UMLS:C1265996",
          "icd11.foundation:1278312485"
        ],
        "synonyms": [
          "LCNEC",
          "large cell NEC",
          "large cell neuroendocrine carcinoma",
          "large-cell neuroendocrine carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A usually aggressive carcinoma composed of large malignant cells which display neuroendocrine characteristics. It is characterized by the presence of high mitotic activity and necrotic changes. The vast majority of cases are positive for neuron-specific enolase. Representative examples include lung, breast, cervical, and thymic neuroendocrine carcinomas."
      },
      "child_count": 12,
      "reference_id": "MONDO:0005057"
    },
    {
      "id": 19965,
      "label": "thymic neuroendocrine carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4255,
        7956,
        19679
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019696",
          "MEDGEN:900590",
          "NCIT:C171031",
          "Orphanet:99869",
          "SCTID:716653001",
          "UMLS:C2210965",
          "icd11.foundation:381956131"
        ],
        "synonyms": [
          "neuroendocrine carcinoma of thymus",
          "thymic neuroendocrine carcinoma",
          "thymus neuroendocrine carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Thymic neuroendocrine carcinoma is a type of thymic epithelial neoplasm displaying evidence of neuroendocrine differentiation."
      },
      "child_count": 15,
      "reference_id": "MONDO:0020516"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6787,
      "label": "large cell neuroendocrine carcinoma"
    },
    {
      "id": 19965,
      "label": "thymic neuroendocrine carcinoma"
    }
  ]
}