{
  "id": 5079,
  "label": "mucoepidermoid esophageal carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003093",
  "properties": {
    "xrefs": [
      "DOID:4686",
      "GARD:0023366",
      "MEDGEN:234232",
      "NCIT:C5343",
      "UMLS:C1333461"
    ],
    "synonyms": [
      "esophagus mucoepidermoid carcinoma",
      "mucoepidermoid carcinoma of the esophagus",
      "mucoepidermoid carcinoma of the oesophagus",
      "oesophagus mucoepidermoid carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A rare carcinoma of the esophagus which contains squamous cells, mucus secreting cells, and cells of an intermediate type. (WHO)"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 5029,
      "label": "mucoepidermoid carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6700,
        8180
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:163",
          "DOID:4531",
          "GARD:0010671",
          "ICDO:8430/1",
          "ICDO:8430/3",
          "MEDGEN:61662",
          "MESH:D018277",
          "MESH:D018298",
          "NCIT:C3772",
          "ONCOTREE:MUCC",
          "UMLS:C0206694",
          "icd11.foundation:287052516"
        ],
        "synonyms": [
          "MEC",
          "mucoepidermoid carcinoma",
          "mucoepidermoid carcinoma (morphologic abnormality)",
          "mucoepidermoid tumor",
          "mucoepidermoid tumour",
          "MUCC",
          "mucoepidermoid tumors",
          "mucoepidermoid tumours",
          "tumor, mucoepidermoid",
          "tumors, mucoepidermoid"
        ],
        "definition": "A carcinoma morphologically characterized the presence of cuboidal mucous cells, goblet-like mucous cells, squamoid cells, cystic changes, and a fibrotic stromal formation. It can occur in several anatomic sites, including parotid gland, oral cavity, paranasal sinus, skin, breast, lung, larynx, and lacrimal ducts. It is classified as low or high grade."
      },
      "child_count": 24,
      "reference_id": "MONDO:0003036"
    },
    {
      "id": 6762,
      "label": "esophageal adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712,
        18977
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4914",
          "EFO:0000478",
          "GARD:0016927",
          "MEDGEN:124636",
          "NCIT:C4025",
          "ONCOTREE:ESCA",
          "Orphanet:99976",
          "SCTID:276803003",
          "UMLS:C0279628",
          "icd11.foundation:829915640"
        ],
        "synonyms": [
          "adenocarcinoma - esophagus",
          "adenocarcinoma - oesophagus",
          "adenocarcinoma of esophagus",
          "adenocarcinoma of oesophagus",
          "adenocarcinoma of the esophagus",
          "adenocarcinoma of the oesophagus",
          "esophageal adenocarcinoma",
          "esophagus adenocarcinoma",
          "oesophageal adenocarcinoma",
          "oesophagus adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A malignant tumor with glandular differentiation arising predominantly from Barrett mucosa in the lower third of the esophagus. Rare examples of esophageal adenocarcinoma deriving from ectopic gastric mucosa in the upper esophagus have also been reported. Grossly, esophageal adenocarcinomas are similar to esophageal squamous cell carcinomas. Microscopically, adenocarcinomas arising in the setting of Barrett esophagus are typically papillary and/or tubular. The prognosis is poor."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005028"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 5029,
      "label": "mucoepidermoid carcinoma"
    },
    {
      "id": 6762,
      "label": "esophageal adenocarcinoma"
    }
  ]
}