{
  "id": 5127,
  "label": "malignant myoepithelioma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003158",
  "properties": {
    "xrefs": [
      "DOID:4838",
      "GARD:0027633",
      "ICDO:8982/3",
      "MEDGEN:90822",
      "NCIT:C7596",
      "ONCOTREE:STMYEC",
      "UMLS:C0334699"
    ],
    "synonyms": [
      "malignant myoepithelioma",
      "myoepithelial carcinoma",
      "myoepithelioma, malignant",
      "myoepithelioma carcinoma",
      "soft tissue myoepithelial carcinoma"
    ],
    "definition": "An infiltrating malignant tumor characterized by the presence of atypical cells with myoepithelial differentiation. Representative examples include malignant breast myoepithelioma and salivary gland myoepithelial carcinoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 4477,
      "label": "myoepithelial tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2661",
          "ICDO:8982/0",
          "ICDO:8982/1",
          "MEDGEN:10235",
          "MESH:D009208",
          "NCIT:C40392",
          "UMLS:C0027070"
        ],
        "synonyms": [
          "myoepithelial neoplasm",
          "myoepithelial tumor",
          "myoepithelioma",
          "benign myoepithelioma"
        ],
        "definition": "A benign or malignant tumor characterized by the presence of cells that show myoepithelial differentiation. Based on its morphologic features, it is classified as benign or malignant. A representative example of benign myoepithelioma is benign salivary gland myoepithelioma. Representative examples of malignant myoepithelioma or myoepithelial carcinoma are malignant breast myoepithelioma and salivary gland myoepithelial carcinoma."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002380"
    },
    {
      "id": 6734,
      "label": "carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-1867",
          "DOID:305",
          "EFO:0000313",
          "ICDO:8010/3",
          "ICDO:8011/3",
          "MEDGEN:2867",
          "MESH:D002277",
          "NCIT:C2916",
          "SCTID:722688002",
          "UMLS:C0007097"
        ],
        "synonyms": [
          "epithelioma",
          "Other carcinoma",
          "carcinoma",
          "carcinoma, malignant",
          "epithelial carcinoma",
          "epithelioma malignant",
          "malignant epithelial neoplasm",
          "malignant epithelial tumor",
          "malignant epithelial tumour",
          "malignant epithelioma"
        ],
        "definition": "A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas."
      },
      "child_count": 98,
      "reference_id": "MONDO:0004993"
    }
  ],
  "children": [
    {
      "id": 5843,
      "label": "malignant breast myoepithelioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4563,
        5127,
        7803
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6776",
          "GARD:0027662",
          "MEDGEN:309375",
          "NCIT:C40395",
          "UMLS:C1518167"
        ],
        "synonyms": [
          "breast malignant myoepithelioma",
          "breast myoepithelial carcinoma",
          "malignant breast myoepithelioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "An invasive malignant tumor that arises from the breast. It is characterized by the presence of spindle-shaped myoepithelial cells. Mitoses are present. Rarely, local recurrences and distant metastases have been reported."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003990"
    }
  ],
  "roots": [
    {
      "id": 4477,
      "label": "myoepithelial tumor"
    },
    {
      "id": 6734,
      "label": "carcinoma"
    }
  ]
}