{
  "id": 5132,
  "label": "cerebellar pilocytic astrocytoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003168",
  "properties": {
    "xrefs": [
      "DOID:4853",
      "GARD:0023392",
      "MEDGEN:91158",
      "NCIT:C6809",
      "SCTID:277507004",
      "UMLS:C0349620"
    ],
    "synonyms": [
      "cerebellar pilocytic astrocytoma",
      "cerebellum pilocytic astrocytoma",
      "pilocytic astrocytoma of cerebellum",
      "pilocytic astrocytoma of the cerebellum"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A WHO Grade 1 astrocytoma which arises in the cerebellum. The tumor is composed of spindle shaped cells with numerous collections of reddish astrocytic fibers called Rosenthal fibers. Over 80% or the cerebellar astrocytomas of childhood are pilocytic. Pilocytic astrocytomas may rarely occur in adults. They are usually treated by surgical resection and in most cases have a favorable prognosis."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 5131,
      "label": "cerebellar astrocytoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4920,
        20687
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4848",
          "GARD:0023391",
          "MEDGEN:196631",
          "NCIT:C9475",
          "UMLS:C0740480"
        ],
        "synonyms": [
          "astrocytoma (excluding glioblastoma) of cerebellum",
          "astrocytoma of cerebellum",
          "astrocytoma of the cerebellum",
          "astrocytoma, cerebellar",
          "cerebellar astrocytoma",
          "cerebellum astrocytoma",
          "cerebellum astrocytoma (excluding glioblastoma)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Benign and malignant neoplasms of the cerebellum that arise from astrocytes. During childhood the majority are benign pilocytic astrocytomas. In adults both benign and relatively higher grade forms may occur. The most common presenting symptoms are headache, nausea, vomiting, ataxia of gait or limb, paresis, diplopia, and dizziness. Objective signs include weakness, long tract signs, dysmetria, gait ataxia, papilledema, and nystagmus. Surgical resection is often curative."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003165"
    },
    {
      "id": 17155,
      "label": "pilocytic astrocytoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17149
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4851",
          "GARD:0009808",
          "ICDO:9421/1",
          "MEDGEN:87271",
          "NANDO:2200084",
          "NCIT:C4047",
          "ONCOTREE:PAST",
          "Orphanet:251612",
          "SCTID:763865009",
          "UMLS:C0334583"
        ],
        "synonyms": [
          "astrocytoma, benign",
          "astrocytoma, pilocytic, benign",
          "grade I astrocytic neoplasm",
          "grade I astrocytic tumor",
          "grade I astrocytic tumour",
          "grade I astrocytoma",
          "pilocytic astrocytoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Pilocytic astrocytoma is a rare subtype of low-grade glioma of the central nervous system characterized by a well circumscribed, often cystic, brain tumor with a discrete mural nodule and long, hair-like projections that extend from the neoplastic astrocytes. Depending on the primary localization and the size of the tumor, patients can present with signs of raised intracranial pressure (headache, vomiting, papilledema), blurred vision, decreased visual acuity, ataxia and/or nystagmus, among others. It is most commonly located in the cerebellum, but occurrence in the hypothalamus, brain stem, optic chiasma, and hemispheres has also been reported."
      },
      "child_count": 4,
      "reference_id": "MONDO:0016691"
    },
    {
      "id": 20620,
      "label": "benign neoplasm of cerebellum",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4920,
        20573
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:196704",
          "NCIT:C4955",
          "SCTID:92050000",
          "UMLS:C0750995",
          "icd11.foundation:664460646"
        ],
        "synonyms": [
          "benign cerebellar neoplasm",
          "benign cerebellar neoplasms",
          "benign cerebellar tumor",
          "benign cerebellar tumour",
          "benign neoplasm of the cerebellum",
          "benign tumor of cerebellum",
          "benign tumor of the cerebellum",
          "benign tumour of cerebellum",
          "benign tumour of the cerebellum",
          "cerebellar neoplasms, benign",
          "cerebellum benign neoplasm",
          "neoplasms, benign, cerebellar",
          "neoplasms, cerebellar, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the cerebellum."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021499"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 5131,
      "label": "cerebellar astrocytoma"
    },
    {
      "id": 17155,
      "label": "pilocytic astrocytoma"
    },
    {
      "id": 20620,
      "label": "benign neoplasm of cerebellum"
    }
  ]
}