{
  "id": 5142,
  "label": "lung adenoid cystic carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003181",
  "properties": {
    "xrefs": [
      "DOID:4872",
      "GARD:0023401",
      "ICD9:162.9",
      "MEDGEN:232709",
      "NCIT:C5666",
      "ONCOTREE:LUACC",
      "SCTID:707466008",
      "UMLS:C1334439"
    ],
    "synonyms": [
      "adenocystic carcinoma of lung",
      "adenocystic carcinoma of the lung",
      "adenoid cystic carcinoma of lung",
      "adenoid cystic carcinoma of the lung",
      "lung adenocystic carcinoma",
      "lung adenoid cystic cancer",
      "lung adenoid cystic carcinoma",
      "pulmonary adenocystic carcinoma",
      "pulmonary adenoid cystic carcinoma",
      "LUACC"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A rare usually indolent lung carcinoma characterized by a cribiform and tubular pattern and the presence of glandular epithelial cells. Clinical symptoms include shortness of breath, cough, wheeze, hemopytsis and chest pain."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6713,
      "label": "adenoid cystic carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080202",
          "EFO:0000231",
          "GARD:0005743",
          "ICDO:8200/3",
          "MEDGEN:41382",
          "MESH:D003528",
          "NCIT:C2970",
          "ONCOTREE:ACYC",
          "UMLS:C0010606",
          "icd11.foundation:2127202862"
        ],
        "synonyms": [
          "adenocystic carcinoma",
          "adenoid cystic cancer",
          "adenoid cystic carcinoma",
          "cylindroid adenocarcinoma",
          "cribriform carcinoma",
          "cylindroma"
        ],
        "definition": "A malignant tumor arising from the epithelial cells. Microscopically, the neoplastic epithelial cells form cylindrical spatial configurations (cribriform or classic type of adenoid cystic carcinoma), cordlike structures (tubular type of adenoid cystic carcinoma), or solid structures (basaloid variant of adenoid cystic carcinoma). Adenoid cystic carcinomas mostly occur in the salivary glands. Other primary sites of involvement include the lacrimal gland, the larynx, and the lungs. Adenoid cystic carcinomas spread along nerve sheaths, resulting in severe pain, and they tend to recur. Lymph node metastases are unusual; hematogenous tumor spread is characteristic."
      },
      "child_count": 17,
      "reference_id": "MONDO:0004971"
    },
    {
      "id": 6791,
      "label": "lung adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712,
        6944
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3910",
          "EFO:0000571",
          "MEDGEN:57744",
          "MESH:C538231",
          "NCIT:C3512",
          "ONCOTREE:LUAD",
          "Orphanet:415268",
          "SCTID:254626006",
          "UMLS:C0152013"
        ],
        "synonyms": [
          "adenocarcinoma of lung",
          "adenocarcinoma of the lung",
          "lung adenocarcinoma",
          "non-small cell lung adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A carcinoma that arises from the lung and is characterized by the presence of malignant glandular epithelial cells. There is a male predilection with a male to female ratio of 2:1. Usually lung adenocarcinoma is asymptomatic and is identified through screening studies or as an incidental radiologic finding. If clinical symptoms are present they include shortness of breath, cough, hemoptysis, chest pain, and fever. Tobacco smoke is a known risk factor."
      },
      "child_count": 22,
      "reference_id": "MONDO:0005061"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6713,
      "label": "adenoid cystic carcinoma"
    },
    {
      "id": 6791,
      "label": "lung adenocarcinoma"
    }
  ]
}