{
  "id": 5145,
  "label": "adenoid cystic breast carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003185",
  "properties": {
    "xrefs": [
      "DOID:4877",
      "EFO:1000071",
      "GARD:0023402",
      "MEDGEN:231031",
      "NCIT:C5130",
      "ONCOTREE:ACBC",
      "UMLS:C1332167"
    ],
    "synonyms": [
      "adenocystic breast carcinoma",
      "adenocystic carcinoma of breast",
      "adenocystic carcinoma of the breast",
      "adenoid cystic breast carcinoma",
      "adenoid cystic carcinoma of breast",
      "adenoid cystic carcinoma of the breast",
      "breast adenoid cystic carcinoma",
      "mammary adenocystic carcinoma",
      "mammary adenoid cystic carcinoma",
      "adenoid cystic breast cancer"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0002657",
        "name": "breast disorder"
      }
    ],
    "definition": "An adenoid cystic carcinoma primarily involving the breast. Three morphologic patterns are seen: cribriform, trabecular, and solid. The prognosis is excellent."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6713,
      "label": "adenoid cystic carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080202",
          "EFO:0000231",
          "GARD:0005743",
          "ICDO:8200/3",
          "MEDGEN:41382",
          "MESH:D003528",
          "NCIT:C2970",
          "ONCOTREE:ACYC",
          "UMLS:C0010606",
          "icd11.foundation:2127202862"
        ],
        "synonyms": [
          "adenocystic carcinoma",
          "adenoid cystic cancer",
          "adenoid cystic carcinoma",
          "cylindroid adenocarcinoma",
          "cribriform carcinoma",
          "cylindroma"
        ],
        "definition": "A malignant tumor arising from the epithelial cells. Microscopically, the neoplastic epithelial cells form cylindrical spatial configurations (cribriform or classic type of adenoid cystic carcinoma), cordlike structures (tubular type of adenoid cystic carcinoma), or solid structures (basaloid variant of adenoid cystic carcinoma). Adenoid cystic carcinomas mostly occur in the salivary glands. Other primary sites of involvement include the lacrimal gland, the larynx, and the lungs. Adenoid cystic carcinomas spread along nerve sheaths, resulting in severe pain, and they tend to recur. Lymph node metastases are unusual; hematogenous tumor spread is characteristic."
      },
      "child_count": 17,
      "reference_id": "MONDO:0004971"
    },
    {
      "id": 6729,
      "label": "breast adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3053,
        6712,
        6730
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3458",
          "EFO:0000304",
          "MEDGEN:167809",
          "NCIT:C5214",
          "UMLS:C0858252"
        ],
        "synonyms": [
          "adenocarcinoma of breast",
          "adenocarcinoma of the breast",
          "breast adenocarcinoma",
          "mammary adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A carcinoma that arises from glandular epithelial cells of the breast"
      },
      "child_count": 39,
      "reference_id": "MONDO:0004988"
    },
    {
      "id": 7803,
      "label": "invasive breast carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6730,
        23004
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000307",
          "MEDGEN:163435",
          "NCIT:C9245",
          "ONCOTREE:BRCA",
          "SCTID:713609000",
          "UMLS:C0853879",
          "icd11.foundation:2090549892"
        ],
        "synonyms": [
          "infiltrating breast cancer",
          "infiltrating breast carcinoma",
          "infiltrating carcinoma of breast",
          "infiltrating carcinoma of the breast",
          "invasive breast cancer",
          "invasive breast carcinoma",
          "invasive carcinoma of breast",
          "invasive carcinoma of the breast",
          "invasive mammary carcinoma",
          "BRCA"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A carcinoma that infiltrates the breast parenchyma. The vast majority are adenocarcinomas arising from the terminal ductal lobular unit (TDLU). Often, the invasive adenocarcinoma co-exists with ductal or lobular carcinoma in situ. It is the most common carcinoma affecting women."
      },
      "child_count": 22,
      "reference_id": "MONDO:0006256"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6713,
      "label": "adenoid cystic carcinoma"
    },
    {
      "id": 6729,
      "label": "breast adenocarcinoma"
    },
    {
      "id": 7803,
      "label": "invasive breast carcinoma"
    }
  ]
}