{
  "id": 5169,
  "label": "apocrine adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003214",
  "properties": {
    "xrefs": [
      "DOID:4933",
      "GARD:0012138",
      "ICDO:8401/3",
      "MEDGEN:569650",
      "NCIT:C4169",
      "UMLS:C0334346"
    ],
    "synonyms": [
      "apocrine adenocarcinoma (morphologic abnormality)",
      "apocrine carcinoma",
      "apocrine gland adenocarcinoma",
      "apocrine gland carcinoma",
      "carcinoma of apocrine gland"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "A carcinoma with apocrine differentiation arising from the sweat glands. It presents as single or multiple nodular lesions which may be ulcerated or hemorrhagic and is usually in the axilla and less often in the anogenital region. It grows in the dermis and infiltrates subcutaneous tissues. It is characterized by the presence of large cells with abundant eosinophilic cytoplasm and large often vesicular nuclei. Most cases are slow growing tumors and have a prolonged course."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 5170,
      "label": "apocrine sweat gland cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4329,
        5570
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4934",
          "MEDGEN:277327",
          "NCIT:C6800",
          "UMLS:C1334561"
        ],
        "synonyms": [
          "apocrine sweat gland cancer",
          "cancer of apocrine sweat gland",
          "malignant apocrine neoplasm",
          "malignant apocrine neoplasm of skin",
          "malignant apocrine neoplasm of the skin",
          "malignant apocrine skin neoplasm",
          "malignant apocrine skin tumor",
          "malignant apocrine skin tumour",
          "malignant apocrine sweat gland neoplasm",
          "malignant apocrine tumor",
          "malignant apocrine tumor of skin",
          "malignant apocrine tumor of the skin",
          "malignant apocrine tumour",
          "malignant apocrine tumour of skin",
          "malignant apocrine tumour of the skin",
          "malignant neoplasm of apocrine sweat gland"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the apocrine sweat gland."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003215"
    },
    {
      "id": 7178,
      "label": "sweat gland carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4329,
        6712,
        8398
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5667",
          "EFO:0005591",
          "ICDO:8400/3",
          "MEDGEN:234685",
          "NCIT:C6938",
          "ONCOTREE:AECA",
          "UMLS:C1412016"
        ],
        "synonyms": [
          "carcinoma of sweat gland",
          "carcinoma of the sweat gland",
          "carcinoma, sweat gland, malignant",
          "sweat gland carcinoma",
          "sweat gland carcinoma/apocrine eccrine carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A carcinoma arising from the sweat glands. Representative examples include tubular carcinoma, spiradenocarcinoma, eccrine carcinoma, hidradenocarcinoma, and apocrine carcinoma."
      },
      "child_count": 12,
      "reference_id": "MONDO:0005524"
    }
  ],
  "children": [
    {
      "id": 5743,
      "label": "ceruminous carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4949,
        5169
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6446",
          "GARD:0027655",
          "ICDO:8420/3",
          "MEDGEN:83135",
          "NCIT:C4176",
          "UMLS:C0334353"
        ],
        "synonyms": [
          "carcinoma, ceruminous gland, malignant",
          "ceruminous adenocarcinoma",
          "ceruminous adenocarcinoma (morphologic abnormality)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "An infiltrating adenocarcinoma derived from ceruminous glands in the external auditory canal."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003880"
    },
    {
      "id": 5744,
      "label": "vulvar apocrine adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5169,
        21365
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6448",
          "GARD:0023712",
          "MEDGEN:384494",
          "NCIT:C40308",
          "UMLS:C2202741"
        ],
        "synonyms": [
          "apocrine adenocarcinoma of mammalian vulva",
          "mammalian vulva apocrine adenocarcinoma",
          "vulvar apocrine adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An apocrine adenocarcinoma that arises from the sweat glands in the vulva."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003881"
    },
    {
      "id": 5793,
      "label": "breast apocrine carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5169,
        7234
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6581",
          "GARD:0027657",
          "MEDGEN:272319",
          "NCIT:C5141",
          "UMLS:C1332316"
        ],
        "synonyms": [
          "apocrine adenocarcinoma of breast",
          "apocrine breast carcinoma",
          "apocrine carcinoma of breast",
          "apocrine carcinoma of the breast",
          "breast apocrine adenocarcinoma",
          "breast apocrine carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "An adenocarcinoma of the breast characterized by the presence of two intermingled cellular components: cells with abundant granular, eosinophilic cytoplasm, and cells with abundant cytoplasm containing fine empty vacuoles."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003934"
    }
  ],
  "roots": [
    {
      "id": 5170,
      "label": "apocrine sweat gland cancer"
    },
    {
      "id": 7178,
      "label": "sweat gland carcinoma"
    }
  ]
}