{
  "id": 5174,
  "label": "gallbladder carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003220",
  "properties": {
    "xrefs": [
      "DOID:4948",
      "EFO:1001956",
      "GARD:0023412",
      "MEDGEN:116001",
      "NCIT:C3844",
      "SCTID:372140005",
      "UMLS:C0235782"
    ],
    "synonyms": [
      "gallbladder cancer",
      "Gall bladder carcinoma (adeno)",
      "Gall bladder carcinoma (adenocarcinoma)",
      "cancer of gallbladder",
      "cancer of the gallbladder",
      "carcinoma of gall bladder",
      "carcinoma of gallbladder",
      "carcinoma of the gallbladder",
      "gall bladder carcinoma",
      "gallbladder carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A carcinoma that arises from epithelial cells of the gall bladder"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 7085,
      "label": "gallbladder cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4587,
        20460
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3121",
          "GARD:0009328",
          "ICD10CM:C23",
          "ICD9:156.0",
          "ICD9:156.8",
          "MEDGEN:57784",
          "NCIT:C7481",
          "ONCOTREE:GBC",
          "SCTID:363353009",
          "UMLS:C0153452",
          "icd11.foundation:922082116"
        ],
        "synonyms": [
          "gallbladder neoplasm",
          "tumor of the gallbladder",
          "tumour of the gallbladder",
          "cancer of gall bladder",
          "gall bladder cancer",
          "malignant gall bladder neoplasm",
          "malignant gallbladder neoplasm",
          "malignant gallbladder tumor",
          "malignant gallbladder tumour",
          "malignant neoplasm of gall bladder",
          "malignant neoplasm of gallbladder",
          "malignant neoplasm of the gallbladder",
          "malignant tumor of gallbladder",
          "malignant tumor of the gallbladder",
          "malignant tumour of gallbladder",
          "malignant tumour of the gallbladder",
          "localised malignant gallbladder neoplasm",
          "localized malignant gallbladder neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the gall bladder"
      },
      "child_count": 10,
      "reference_id": "MONDO:0005411"
    },
    {
      "id": 7738,
      "label": "digestive system carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4587,
        6734
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050922",
          "EFO:1000218",
          "HP:0002672",
          "MEDGEN:57467",
          "NCIT:C96963",
          "UMLS:C0151544"
        ],
        "synonyms": [
          "carcinoma of digestive system",
          "carcinoma of the gastrointestinal system",
          "digestive system carcinoma",
          "gastrointestinal carcinoma",
          "gastrointestinal carcinoma (disease)",
          "gastrointestinal system carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A malignant neoplasm that arises from the epithelium of any part of the digestive system. Representative examples include colorectal carcinoma, esophageal carcinoma, and pancreatic carcinoma."
      },
      "child_count": 32,
      "reference_id": "MONDO:0006181"
    }
  ],
  "children": [
    {
      "id": 2872,
      "label": "gall bladder carcinoma in situ",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5174,
        6433
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050612",
          "GARD:0022758",
          "MEDGEN:87523",
          "NCIT:C4439",
          "UMLS:C0345911"
        ],
        "synonyms": [
          "carcinoma in situ of gall bladder",
          "gall bladder in situ carcinoma",
          "stage 0 gall bladder carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A carcinoma in situ involving a gall bladder."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000373"
    },
    {
      "id": 7768,
      "label": "gallbladder adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5174,
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3500",
          "EFO:1000262",
          "GARD:0024333",
          "MEDGEN:76009",
          "NCIT:C9166",
          "UMLS:C0279651",
          "icd11.foundation:15874829"
        ],
        "synonyms": [
          "adenocarcinoma of gallbladder",
          "adenocarcinoma of the gallbladder",
          "gall bladder adenocarcinoma",
          "gallbladder adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A carcinoma that arises from glandular epithelial cells of the gall bladder."
      },
      "child_count": 8,
      "reference_id": "MONDO:0006215"
    },
    {
      "id": 7772,
      "label": "gallbladder small cell neuroendocrine carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        5174,
        21455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7133",
          "EFO:1000266",
          "GARD:0024335",
          "MEDGEN:232229",
          "NCIT:C6763",
          "UMLS:C1333759"
        ],
        "synonyms": [
          "Oat cell carcinoma of gallbladder",
          "Oat cell carcinoma of the gallbladder",
          "gall bladder small cell carcinoma",
          "gallbladder Oat cell carcinoma",
          "gallbladder small cell NEC",
          "gallbladder small cell carcinoma",
          "gallbladder small cell neuroendocrine carcinoma",
          "small cell carcinoma of gall bladder",
          "small cell carcinoma of gallbladder",
          "small cell carcinoma of the gallbladder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the gallbladder. It is characterized by the presence of malignant small cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006219"
    },
    {
      "id": 7773,
      "label": "gallbladder squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5174,
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5535",
          "EFO:1000267",
          "GARD:0024336",
          "MEDGEN:83539",
          "NCIT:C9170",
          "UMLS:C0279658"
        ],
        "synonyms": [
          "epidermoid carcinoma of gallbladder",
          "epidermoid carcinoma of the gallbladder",
          "epidermoid gallbladder carcinoma",
          "gall bladder squamous cell carcinoma",
          "gallbladder squamous cell cancer",
          "gallbladder squamous cell carcinoma",
          "squamous cell carcinoma of gallbladder",
          "squamous cell carcinoma of the gallbladder",
          "squamous cell gallbladder carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A carcinoma that arises from the gallbladder. It is composed entirely by malignant squamous epithelial cells."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006220"
    },
    {
      "id": 7973,
      "label": "undifferentiated gallbladder carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5174,
        7257
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000604",
          "GARD:0024427",
          "MEDGEN:76010",
          "NCIT:C9167",
          "UMLS:C0279653"
        ],
        "synonyms": [
          "anaplastic carcinoma of gallbladder",
          "anaplastic carcinoma of the gallbladder",
          "anaplastic gallbladder carcinoma",
          "gall bladder undifferentiated carcinoma",
          "gallbladder undifferentiated carcinoma",
          "undifferentiated carcinoma of gallbladder",
          "undifferentiated carcinoma of the gallbladder",
          "undifferentiated gallbladder cancer",
          "undifferentiated gallbladder carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A carcinoma without evidence of differentiation arising from the gallbladder. The most common variant is the spindle and giant cell type which resembles a sarcoma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006476"
    }
  ],
  "roots": [
    {
      "id": 7085,
      "label": "gallbladder cancer"
    },
    {
      "id": 7738,
      "label": "digestive system carcinoma"
    }
  ]
}