{
  "id": 5175,
  "label": "central nervous system melanocytic neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003222",
  "properties": {
    "xrefs": [
      "DOID:4955",
      "GARD:0009422",
      "MEDGEN:1809168",
      "NCIT:C5504",
      "SCTID:277523004",
      "UMLS:C5670969"
    ],
    "synonyms": [
      "CNS melanocytic neoplasm",
      "CNS melanocytic tumor",
      "CNS melanocytic tumour",
      "central nervous system melanocytic neoplasm",
      "central nervous system melanocytic neoplasms",
      "central nervous system melanocytic tumor",
      "central nervous system melanocytic tumour",
      "melanocytic neoplasm of CNS",
      "melanocytic neoplasm of central nervous system",
      "melanocytic neoplasm of the CNS",
      "melanocytic neoplasm of the central nervous system",
      "melanocytic tumor of CNS",
      "melanocytic tumor of central nervous system",
      "melanocytic tumor of the central nervous system",
      "melanocytic tumour of CNS",
      "melanocytic tumour of central nervous system",
      "melanocytic tumour of the CNS",
      "melanocytic tumour of the central nervous system"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A primary tumor of the central nervous system that arises from leptomeningeal melanocytes. It may present as a diffuse proliferative leptomeningeal process (often as a component of the neurocutaneous melanosis complex) or as a distinct mass lesion."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4753,
      "label": "central nervous system cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7479,
        7694
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3620",
          "EFO:0000326",
          "GARD:0027614",
          "ICD9:239.7",
          "MEDGEN:87593",
          "MESH:D016543",
          "NANDO:2100007",
          "NCIT:C4627",
          "SCTID:126951006",
          "UMLS:C0348374"
        ],
        "synonyms": [
          "CNS neoplasm",
          "central nervous system tumor",
          "central nervous system tumour",
          "CNS cancer",
          "CNS malignant neoplasms",
          "CNS neoplasms, malignant",
          "cancer of CNS",
          "cancer of central nervous system",
          "cancer of the CNS",
          "cancer of the central nervous system",
          "central nervous system cancer",
          "central nervous system neoplasms, malignant",
          "central nervous system tumours",
          "malignant CNS neoplasm",
          "malignant CNS neoplasms",
          "malignant CNS tumor",
          "malignant CNS tumour",
          "malignant central nervous system neoplasm",
          "malignant central nervous system tumor",
          "malignant central nervous system tumour",
          "malignant neoplasm of CNS",
          "malignant neoplasm of central nervous system",
          "malignant neoplasm of the CNS",
          "malignant neoplasm of the central nervous system",
          "malignant tumor of CNS",
          "malignant tumor of central nervous system",
          "malignant tumor of the CNS",
          "malignant tumor of the central nervous system",
          "malignant tumour of CNS",
          "malignant tumour of central nervous system",
          "malignant tumour of the CNS",
          "malignant tumour of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the central nervous system"
      },
      "child_count": 40,
      "reference_id": "MONDO:0002714"
    },
    {
      "id": 20380,
      "label": "melanocytic neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798,
        20691
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:224910",
          "MESH:D018326",
          "NCIT:C7058",
          "SCTID:399956005",
          "UMLS:C1302746"
        ],
        "synonyms": [
          "melanocytic neoplasm",
          "melanomas and nevi"
        ]
      },
      "child_count": 6,
      "reference_id": "MONDO:0021143"
    }
  ],
  "children": [
    {
      "id": 5732,
      "label": "diffuse meningeal melanocytosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5175
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6379",
          "GARD:0027654",
          "ICDO:8728/0",
          "MEDGEN:226841",
          "NCIT:C6890",
          "UMLS:C1266112"
        ],
        "synonyms": [
          "diffuse melanocytosis",
          "diffuse melanocytosis (morphologic abnormality)",
          "diffuse melanosis",
          "meningeal melanocytosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A diffuse or multifocal proliferation of uniform nevoid polygonal cells in the leptomeninges. Cells may spread into the Virchow-Robin spaces without frank invasion of the brain. Diffuse melanocytosis carries a poor prognosis even in the absence of histologic malignancy. (WHO)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0003867"
    },
    {
      "id": 17194,
      "label": "meningeal melanocytoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5175
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5900",
          "GARD:0020740",
          "ICDO:8728/1",
          "MEDGEN:226842",
          "NCIT:C4662",
          "Orphanet:252046",
          "SCTID:277527003",
          "UMLS:C1266113"
        ],
        "synonyms": [
          "leptomeningeal melanocytoma",
          "melanocytoma of meninges",
          "melanocytoma of the meninges",
          "meninges melanocytoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A usually well differentiated melanocytic neoplasm arising from the meninges. It is characterized by the presence of epithelioid, fusiform, polyhedral, and spindle melanocytes without evidence of hemorrhage, necrosis, or high mitotic activity. Presenting symptoms include headache, vomiting, and neurological manifestations. Complete excision is usually curative."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016746"
    },
    {
      "id": 17195,
      "label": "primary melanoma of the central nervous system",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5175,
        7853
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0012016",
          "MEDGEN:578849",
          "NCIT:C5505",
          "ONCOTREE:PCNSM",
          "Orphanet:252050",
          "UMLS:C0349626",
          "icd11.foundation:539210076"
        ],
        "synonyms": [
          "CNS melanoma",
          "Central nervous system melanoma",
          "central nervous system melanoma",
          "central nervous system melanoma (disease)",
          "melanoma (disease) of central nervous system",
          "melanoma of CNS",
          "melanoma of central nervous system",
          "melanoma of the CNS",
          "melanoma of the Central nervous system",
          "malignant melanoma of meninges",
          "primary CNS melanoma",
          "primary melanoma of the CNS",
          "primary meningeal melanoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A melanoma that affects the central nervous system. It is characterized by pleomorphism, melanin pigmentation, a high mitotic rate, necrosis, and hemorrhage. It is a highly aggressive and radioresistant tumor. The prognosis is usually poor."
      },
      "child_count": 6,
      "reference_id": "MONDO:0016747"
    }
  ],
  "roots": [
    {
      "id": 4753,
      "label": "central nervous system cancer"
    },
    {
      "id": 20380,
      "label": "melanocytic neoplasm"
    }
  ]
}