{
  "id": 5196,
  "label": "esophageal granular cell tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003251",
  "properties": {
    "xrefs": [
      "DOID:5040",
      "GARD:0023422",
      "MEDGEN:234228",
      "NCIT:C5700",
      "UMLS:C1333448",
      "icd11.foundation:1070074406"
    ],
    "synonyms": [
      "esophageal granular cell myoblastoma",
      "esophageal granular cell neoplasm",
      "esophageal granular cell tumor",
      "esophagus granular cell tumor",
      "granular cell esophageal tumor",
      "granular cell esophageal tumour",
      "granular cell esophagus myoblastoma",
      "granular cell esophagus neoplasm",
      "granular cell esophagus tumor",
      "granular cell myoblastoma of esophagus",
      "granular cell myoblastoma of oesophagus",
      "granular cell myoblastoma of the esophagus",
      "granular cell myoblastoma of the oesophagus",
      "granular cell neoplasm of esophagus",
      "granular cell neoplasm of oesophagus",
      "granular cell neoplasm of the esophagus",
      "granular cell neoplasm of the oesophagus",
      "granular cell oesophagus myoblastoma",
      "granular cell oesophagus neoplasm",
      "granular cell oesophagus tumour",
      "granular cell tumor of esophagus",
      "granular cell tumor of the esophagus",
      "granular cell tumour of oesophagus",
      "granular cell tumour of the oesophagus",
      "oesophagus granular cell tumour",
      "malignant granular cell esophageal tumor",
      "malignant granular cell esophageal tumour"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A tumor that usually presents with small nodules or small sessile polyps, predominantly in the distal esophagus. Histologically, it is composed of sheets of oval to polygonal cells with a small central nucleus and abundant granular cytoplasm. This is usually a benign tumor. (WHO, 2000) -- 2003"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7788,
      "label": "granular cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4613
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2411",
          "EFO:1000284",
          "GARD:0009618",
          "ICD9:215.9",
          "ICDO:9580/0",
          "MEDGEN:88345",
          "MESH:C535558",
          "MESH:D016586",
          "NCIT:C3474",
          "ONCOTREE:GCT",
          "SCTID:404035005",
          "UMLS:C0085167"
        ],
        "synonyms": [
          "Abrikossoff tumor",
          "Abrikossoff tumour",
          "Abrikossoff's tumor",
          "Abrikossoff's tumour",
          "granular cell myoblastoma",
          "granular cell neoplasm",
          "granular cell nerve sheath tumor",
          "granular cell nerve sheath tumour",
          "granular cell schwannoma",
          "granular cell tumor",
          "granular cell tumor (morphologic abnormality)",
          "granular cell tumour (morphologic abnormality)",
          "granular cell tumor NOS (morphologic abnormality)",
          "granular cell tumour NOS (morphologic abnormality)",
          "neoplasm of granular cell",
          "Abrikosoff's granulous cell tumor",
          "Abrikosoff's granulous cell tumour",
          "Abrikosoff's tumor",
          "Abrikosoff's tumour",
          "Abrikosov's tumor",
          "Abrikosov's tumour",
          "Abrikosov’s tumor",
          "Abrikosov’s tumour",
          "GCT",
          "giant granulocellular Abrikosov's tumor",
          "giant granulocellular Abrikosov's tumour",
          "malignant variant of Abrikosov's tumor",
          "malignant variant of Abrikosov's tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An unusual benign or malignant neoplasm characterized by the presence of neoplastic large polygonal cells with granular, eosinophilic cytoplasm which contains abundant lysosomes. It was originally thought to be a tumor originating from muscle cells and was named granular cell myoblastoma. Subsequent studies have suggested a derivation from Schwann cells. It affects females more often than males and it usually presents as a solitary mass. A minority of patients have multiple tumors. It can arise from many anatomic sites including the posterior pituitary gland, skin, oral cavity, esophagus, stomach, heart, mediastinum, and breast."
      },
      "child_count": 9,
      "reference_id": "MONDO:0006235"
    },
    {
      "id": 20522,
      "label": "neoplasm of esophagus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5629,
        20434
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:4547",
          "NCIT:C3028",
          "SCTID:126817006",
          "UMLS:C0014859"
        ],
        "synonyms": [
          "esophageal neoplasm",
          "esophageal neoplasms, benign and malignant",
          "esophageal tumor",
          "esophageal tumors",
          "esophageal tumour",
          "esophageal tumours",
          "esophagus neoplasm",
          "esophagus neoplasm (disease)",
          "esophagus tumor",
          "neoplasm of esophagus",
          "neoplasm of the esophagus",
          "neoplasm of the oesophagus",
          "oesophagus neoplasm",
          "oesophagus neoplasm (disease)",
          "oesophagus tumour",
          "tumor of esophagus",
          "tumor of the esophagus",
          "tumour of oesophagus",
          "tumour of the oesophagus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the esophagus."
      },
      "child_count": 10,
      "reference_id": "MONDO:0021355"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7788,
      "label": "granular cell tumor"
    },
    {
      "id": 20522,
      "label": "neoplasm of esophagus"
    }
  ]
}