{
  "id": 5201,
  "label": "neurohypophysis granular cell tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003256",
  "properties": {
    "xrefs": [
      "DOID:5047",
      "EFO:1000285",
      "GARD:0023427",
      "ICDO:9582/0",
      "MEDGEN:232255",
      "NCIT:C7017",
      "SCTID:699331002",
      "UMLS:C1333873"
    ],
    "synonyms": [
      "granular cell tumor of Neurohypophysis",
      "granular cell tumor of neurohypophysis",
      "granular cell tumor of the Neurohypophysis (WHO grade I)",
      "granular cell tumor of the neurohypophysis",
      "granular cell tumor of the posterior pituitary gland",
      "granular cell tumour of Neurohypophysis",
      "granular cell tumour of neurohypophysis",
      "granular cell tumour of the Neurohypophysis (WHO grade I)",
      "granular cell tumour of the neurohypophysis",
      "granular cell tumour of the posterior pituitary gland",
      "neurohypophysis granular cell tumor"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A generally benign intrasellar and/or suprasellar mass arising from the neurohypophysis or infundibulum. It is composed of nests of large cells with granular, eosinophilic cytoplasm due to abundant intracytoplasmic lysosomes. It generally has a slow progression and lacks invasive growth. (Adapted from WHO)"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 5202,
      "label": "posterior pituitary gland neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17888,
        23822
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5048",
          "GARD:0023428",
          "MEDGEN:235368",
          "NCIT:C7157",
          "UMLS:C1334957"
        ],
        "synonyms": [
          "Neurohypophysis neoplasm",
          "Neurohypophysis tumor",
          "Neurohypophysis tumour",
          "PITUICYTOMA, benign",
          "neoplasm of neurohypophysis",
          "neurohypophysis neoplasm",
          "neurohypophysis neoplasm (disease)",
          "neurohypophysis tumor",
          "neurohypophysis tumour",
          "posterior pituitary gland neoplasm",
          "posterior pituitary gland tumor",
          "posterior pituitary gland tumour",
          "posterior pituitary neoplasm",
          "posterior pituitary tumor",
          "posterior pituitary tumour",
          "tumor of neurohypophysis",
          "tumour of neurohypophysis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A low-grade neoplasm that arises from the neurohypophysis. It includes the granular cell tumor of the neurohypophysis and pituicytoma."
      },
      "child_count": 8,
      "reference_id": "MONDO:0003257"
    },
    {
      "id": 7788,
      "label": "granular cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4613
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2411",
          "EFO:1000284",
          "GARD:0009618",
          "ICD9:215.9",
          "ICDO:9580/0",
          "MEDGEN:88345",
          "MESH:C535558",
          "MESH:D016586",
          "NCIT:C3474",
          "ONCOTREE:GCT",
          "SCTID:404035005",
          "UMLS:C0085167"
        ],
        "synonyms": [
          "Abrikossoff tumor",
          "Abrikossoff tumour",
          "Abrikossoff's tumor",
          "Abrikossoff's tumour",
          "granular cell myoblastoma",
          "granular cell neoplasm",
          "granular cell nerve sheath tumor",
          "granular cell nerve sheath tumour",
          "granular cell schwannoma",
          "granular cell tumor",
          "granular cell tumor (morphologic abnormality)",
          "granular cell tumour (morphologic abnormality)",
          "granular cell tumor NOS (morphologic abnormality)",
          "granular cell tumour NOS (morphologic abnormality)",
          "neoplasm of granular cell",
          "Abrikosoff's granulous cell tumor",
          "Abrikosoff's granulous cell tumour",
          "Abrikosoff's tumor",
          "Abrikosoff's tumour",
          "Abrikosov's tumor",
          "Abrikosov's tumour",
          "Abrikosov’s tumor",
          "Abrikosov’s tumour",
          "GCT",
          "giant granulocellular Abrikosov's tumor",
          "giant granulocellular Abrikosov's tumour",
          "malignant variant of Abrikosov's tumor",
          "malignant variant of Abrikosov's tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An unusual benign or malignant neoplasm characterized by the presence of neoplastic large polygonal cells with granular, eosinophilic cytoplasm which contains abundant lysosomes. It was originally thought to be a tumor originating from muscle cells and was named granular cell myoblastoma. Subsequent studies have suggested a derivation from Schwann cells. It affects females more often than males and it usually presents as a solitary mass. A minority of patients have multiple tumors. It can arise from many anatomic sites including the posterior pituitary gland, skin, oral cavity, esophagus, stomach, heart, mediastinum, and breast."
      },
      "child_count": 9,
      "reference_id": "MONDO:0006235"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 5202,
      "label": "posterior pituitary gland neoplasm"
    },
    {
      "id": 7788,
      "label": "granular cell tumor"
    }
  ]
}