{
  "id": 5202,
  "label": "posterior pituitary gland neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003257",
  "properties": {
    "xrefs": [
      "DOID:5048",
      "GARD:0023428",
      "MEDGEN:235368",
      "NCIT:C7157",
      "UMLS:C1334957"
    ],
    "synonyms": [
      "Neurohypophysis neoplasm",
      "Neurohypophysis tumor",
      "Neurohypophysis tumour",
      "PITUICYTOMA, benign",
      "neoplasm of neurohypophysis",
      "neurohypophysis neoplasm",
      "neurohypophysis neoplasm (disease)",
      "neurohypophysis tumor",
      "neurohypophysis tumour",
      "posterior pituitary gland neoplasm",
      "posterior pituitary gland tumor",
      "posterior pituitary gland tumour",
      "posterior pituitary neoplasm",
      "posterior pituitary tumor",
      "posterior pituitary tumour",
      "tumor of neurohypophysis",
      "tumour of neurohypophysis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A low-grade neoplasm that arises from the neurohypophysis. It includes the granular cell tumor of the neurohypophysis and pituicytoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 17888,
      "label": "pituitary tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4223,
        4759,
        5314,
        7638,
        8247
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021253",
          "ICD9:239.7",
          "MEDGEN:19326",
          "NCIT:C3330",
          "Orphanet:304055",
          "SCTID:127024001",
          "UMLS:C0032019"
        ],
        "synonyms": [
          "neoplasm of pituitary",
          "neoplasm of pituitary gland",
          "neoplasm of the pituitary",
          "neoplasm of the pituitary gland",
          "pituitary gland neoplasm",
          "pituitary gland tumor",
          "pituitary gland tumour",
          "pituitary neoplasm",
          "pituitary tumor",
          "tumor of pituitary",
          "tumor of pituitary gland",
          "tumor of the pituitary",
          "tumor of the pituitary gland",
          "tumour of pituitary",
          "tumour of pituitary gland",
          "tumour of the pituitary",
          "tumour of the pituitary gland"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm affecting the pituitary gland. The vast majority are adenomas arising from the anterior lobe of the pituitary gland."
      },
      "child_count": 45,
      "reference_id": "MONDO:0017611"
    },
    {
      "id": 23822,
      "label": "neuroendocrine disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6799,
        6875
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1843486",
          "UMLS:C0541403"
        ],
        "synonyms": [
          "neuroendocrine system disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A disease or disorder that affects the neuroendocrine gland, any of the organized aggregations of cells that function as secretory or excretory organs and that release hormones in response to neural stimuli."
      },
      "child_count": 8,
      "reference_id": "MONDO:0100070"
    }
  ],
  "children": [
    {
      "id": 5201,
      "label": "neurohypophysis granular cell tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5202,
        7788
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5047",
          "EFO:1000285",
          "GARD:0023427",
          "ICDO:9582/0",
          "MEDGEN:232255",
          "NCIT:C7017",
          "SCTID:699331002",
          "UMLS:C1333873"
        ],
        "synonyms": [
          "granular cell tumor of Neurohypophysis",
          "granular cell tumor of neurohypophysis",
          "granular cell tumor of the Neurohypophysis (WHO grade I)",
          "granular cell tumor of the neurohypophysis",
          "granular cell tumor of the posterior pituitary gland",
          "granular cell tumour of Neurohypophysis",
          "granular cell tumour of neurohypophysis",
          "granular cell tumour of the Neurohypophysis (WHO grade I)",
          "granular cell tumour of the neurohypophysis",
          "granular cell tumour of the posterior pituitary gland",
          "neurohypophysis granular cell tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A generally benign intrasellar and/or suprasellar mass arising from the neurohypophysis or infundibulum. It is composed of nests of large cells with granular, eosinophilic cytoplasm due to abundant intracytoplasmic lysosomes. It generally has a slow progression and lacks invasive growth. (Adapted from WHO)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0003256"
    },
    {
      "id": 6253,
      "label": "pituitary stalk meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4996,
        4997,
        5202
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8058",
          "GARD:0024010",
          "MEDGEN:233858",
          "NCIT:C5311",
          "UMLS:C1335422"
        ],
        "synonyms": [
          "meningioma (disease) of pituitary stalk",
          "meningioma of pituitary stalk",
          "meningioma of the pituitary stalk",
          "pituitary stalk meningioma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A meningioma that affects the pituitary stalk."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004447"
    },
    {
      "id": 7895,
      "label": "pituicytoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4246,
        5133,
        5202,
        17149
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081280",
          "EFO:1000477",
          "GARD:0020711",
          "ICD9:237.0",
          "ICDO:9432/1",
          "MEDGEN:458776",
          "NCIT:C94524",
          "ONCOTREE:PTCY",
          "Orphanet:251623",
          "SCTID:608817003",
          "UMLS:C2986550"
        ],
        "synonyms": [
          "pituicytoma",
          "pituicytoma (WHO grade I)",
          "posterior pituitary astrocytoma",
          "PTCY"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An extremely rare, WHO grade I, circumscribed and slow-growing tumor that arises from the neurohypophysis or infundibulum and described in adults. It is characterized by the presence of elongated, spindle-shaped neoplastic glial cells that form storiform patterns or interlacing fascicular arrangements. Signs and symptoms include visual disturbances, headache, amenorrhea, and decreased libido."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006372"
    },
    {
      "id": 25261,
      "label": "spindle cell oncocytoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5202
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081306",
          "GARD:0026638",
          "MEDGEN:458787",
          "NCIT:C94537",
          "UMLS:C2986561"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A posterior pituitary benign neoplasm that is characterized by the presence of spindle cells with eosinophilic, granular cytoplasm forming fascicles."
      },
      "child_count": 0,
      "reference_id": "MONDO:0858960"
    }
  ],
  "roots": [
    {
      "id": 17888,
      "label": "pituitary tumor"
    },
    {
      "id": 23822,
      "label": "neuroendocrine disorder"
    }
  ]
}