{
  "id": 5208,
  "label": "basosquamous carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003264",
  "properties": {
    "xrefs": [
      "DOID:5063",
      "EFO:1000529",
      "ICDO:8094/3",
      "MEDGEN:2841",
      "MESH:D002281",
      "NCIT:C2922",
      "UMLS:C0007118"
    ],
    "synonyms": [
      "basosquamous carcinoma",
      "basosquamous cell carcinoma",
      "basosquamous tumor, malignant",
      "metatypical carcinoma (morphologic abnormality)",
      "skin basosquamous cell carcinoma",
      "skin mixed basal and squamous cell carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "A basal cell carcinoma which displays squamous differentiation. The neoplastic cells have more abundant cytoplasm with more marked keratinization than typical basal cell carcinomas. It usually has a more aggressive clinical course compared to typical basal cell carcinoma, and it may produce regional or widespread metastases."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7027,
      "label": "skin basal cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4707,
        20201
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-2719",
          "DOID:2513",
          "HP:0002671",
          "ICDO:8090/3",
          "MEDGEN:1648304",
          "NCIT:C2921",
          "ONCOTREE:BCC",
          "SCTID:254701007",
          "UMLS:C4721806"
        ],
        "synonyms": [
          "BCC",
          "basal cell cancer",
          "basal cell carcinoma",
          "basal cell tumor",
          "basal cell tumour",
          "basal cell tumour (morphologic abnormality)",
          "malignant basal cell tumour",
          "malignant basal cell tumour (morphologic abnormality)",
          "basal cell carcinoma of skin",
          "basal cell carcinoma of the skin",
          "basal cell epithelioma",
          "basal cell skin carcinoma",
          "skin basal cell cancer",
          "skin basal cell carcinoma",
          "epithelioma basal cell"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "The most frequently seen skin cancer. It arises from basal cells of the epidermis and pilosebaceous units. Clinically it is divided into the following types: nodular, ulcerative, superficial, multicentric, erythematous, and sclerosing or morphea-like. More than 95% of these carcinomas occur in patients over 40. They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck and the remaining 15% on the trunk and extremities. Basal cell carcinoma usually grows in a slow and indolent fashion. However, if untreated, the tumor may invade the subcutaneous fat, skeletal muscle and bone. Distant metastases are rare. Excision, curettage and irradiation cure most basal cell carcinomas."
      },
      "child_count": 50,
      "reference_id": "MONDO:0005341"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7027,
      "label": "skin basal cell carcinoma"
    }
  ]
}