{ "id": 5215, "label": "thoracic cancer", "model": { "label": "Mondo Disease Ontology (MONDO)", "source": 0 }, "type_id": 0, "reference_id": "MONDO:0003274", "properties": { "xrefs": [ "DOID:5093", "ICD10CM:C76.1", "ICD9:195.1", "MEDGEN:56320", "NCIT:C3576", "SCTID:188361007", "UMLS:C0153661" ], "synonyms": [ "thoracic tumor", "thoracic tumour", "thorax neoplasm", "tumor of thorax", "tumour of thorax", "cancer of thoracic segment of trunk", "malignant neoplasm of the thorax", "malignant neoplasm of thoracic segment of trunk", "malignant neoplasm of thorax", "malignant thoracic neoplasm", "malignant thoracic segment of trunk neoplasm", "malignant thoracic tumor", "malignant thoracic tumour", "malignant tumor of the thorax", "malignant tumor of thorax", "malignant tumour of the thorax", "malignant tumour of thorax", "thoracic segment of trunk cancer" ], "definition": "A primary or metastatic malignant neoplasm affecting the tissues of the thorax." }, "isLeaf": false, "isRoot": false, "child_count": 8, "parents": [ { "id": 6733, "label": "cancer", "isLeaf": false, "isRoot": false, "parents": [ 6798 ], "type_id": 0, "properties": { "xrefs": [ "DOID:0050686", "DOID:0050687", "DOID:162", "ICD9:195.8", "ICD9:199", "ICD9:199.1", "ICDO:8000/3", "MEDGEN:14297", "NCIT:C9305", "ONCOTREE:MT", "SCTID:363346000", "UMLS:C0006826", "birnlex:406" ], "synonyms": [ "CA", "cancer", "cell type cancer", "malignancy", "malignant growth", "malignant neoplasm", "malignant neoplasm (disease)", "malignant neoplastic disease", "malignant tumor", "malignant tumour", "neoplasm (disease), malignant", "neoplasm, malignant", "MT" ], "definition": "A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas (adenocarcinomas or squamous cell carcinomas), Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas." }, "child_count": 33, "reference_id": "MONDO:0004992" }, { "id": 20518, "label": "neoplasm of thorax", "isLeaf": false, "isRoot": false, "parents": [ 6798 ], "type_id": 0, "properties": { "xrefs": [ "ICD10CM:C30-C39", "ICD9:239.89", "MEDGEN:11793", "NCIT:C3406", "SCTID:255058005", "UMLS:C0039981" ], "synonyms": [ "neoplasm of the thorax", "neoplasm of thoracic segment of trunk", "thoracic neoplasm", "thoracic segment of trunk neoplasm", "thoracic segment of trunk neoplasm (disease)", "thoracic segment of trunk tumor", "thoracic segment of trunk tumour", "thoracic tumor", "thoracic tumour", "tumor of the thorax", "tumor of thoracic segment of trunk", "tumor of thorax", "tumour of the thorax", "tumour of thoracic segment of trunk", "tumour of thorax" ], "definition": "A neoplasm (disease) that involves the thoracic segment of trunk." }, "child_count": 11, "reference_id": "MONDO:0021350" } ], "children": [ { "id": 3568, "label": "heart cancer", "isLeaf": false, "isRoot": false, "parents": [ 4237, 5215, 20427 ], "type_id": 0, "properties": { "xrefs": [ "DOID:117", "GARD:0027573", "ICD10CM:C38.0", "ICD9:164.1", "MEDGEN:57787", "MESH:D006338", "NCIT:C3548", "UMLS:C0153500" ], "synonyms": [ "Cardiac tumor", "Cardiac tumour", "tumor of heart", "tumour of heart", "Cardiac neoplasm, malignant", "cancer of heart", "heart cancer", "malignant Cardiac neoplasm", "malignant Cardiac tumor", "malignant Cardiac tumour", "malignant heart neoplasm", "malignant heart tumor", "malignant heart tumour", "malignant neoplasm of heart", "malignant neoplasm of the heart", "malignant tumor of heart", "malignant tumor of the heart", "malignant tumour of heart", "malignant tumour of the heart" ], "categories": [ { "ref": "MONDO:0004995", "name": "cardiovascular disorder" } ], "definition": "A malignant neoplasm involving the heart" }, "child_count": 21, "reference_id": "MONDO:0001340" }, { "id": 5214, "label": "sternum cancer", "isLeaf": false, "isRoot": false, "parents": [ 4262, 5215, 20675 ], "type_id": 0, "properties": { "xrefs": [ "DOID:5090", "GARD:0023432", "MEDGEN:277996", "NCIT:C8408", "UMLS:C1382025" ], "synonyms": [ "neoplasm of sternum", "sternal tumour", "cancer of sternum", "malignant neoplasm of sternum", "malignant neoplasm of the sternum", "malignant sternal neoplasm", "malignant sternal tumor", "malignant sternal tumour", "malignant sternum neoplasm", "malignant tumor of sternum", "malignant tumor of the sternum", "malignant tumour of sternum", "malignant tumour of the sternum", "sternum cancer" ], "categories": [ { "ref": "MONDO:0002081", "name": "musculoskeletal system disorder" }, { "ref": "MONDO:0003900", "name": "connective tissue disorder" } ], "definition": "A malignant neoplasm involving the sternum" }, "child_count": 3, "reference_id": "MONDO:0003273" }, { "id": 7455, "label": "mediastinal cancer", "isLeaf": false, "isRoot": false, "parents": [ 5215, 20542 ], "type_id": 0, "properties": { "xrefs": [ "DOID:5559", "EFO:0007362", "ICD9:164.9", "MEDGEN:56308", "MESH:D008479", "NCIT:C3549", "SCTID:363494000", "UMLS:C0153504" ], "synonyms": [ "mediastinal tumor", "mediastinal tumour", "tumor of mediastinum", "tumour of mediastinum", "cancer of mediastinum", "cancer of the mediastinum", "malignant mediastinal neoplasm", "malignant mediastinal tumor", "malignant mediastinal tumour", "malignant mediastinum neoplasm", "malignant neoplasm of mediastinum", "malignant neoplasm of the mediastinum", "malignant tumor of mediastinum", "malignant tumor of the mediastinum", "malignant tumour of mediastinum", "malignant tumour of the mediastinum", "mediastinal cancer", "mediastinum cancer" ], "definition": "A malignant neoplasm involving the mediastinum" }, "child_count": 12, "reference_id": "MONDO:0005843" }, { "id": 7668, "label": "Askin tumor", "isLeaf": true, "isRoot": false, "parents": [ 5215, 18390 ], "type_id": 0, "properties": { "xrefs": [ "DOID:0050608", "EFO:1000095", "GARD:0024291", "ICDO:9365/3", "MEDGEN:209112", "MESH:C563168", "NCIT:C7542", "UMLS:C0877849" ], "synonyms": [ "Askin tumor", "Askin's tumor", "PNET of thoracopulmonary region", "peripheral neuroectodermal tumor of thoracopulmonary region", "peripheral neuroectodermal tumour of thoracopulmonary region", "small cell tumor of thoracopulmonary region", "small cell tumour of thoracopulmonary region" ], "categories": [ { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "A primitive neuroectodermal tumor (small round blue cell tumor) of the thorax which can involve the periosteum, thoracic wall and/or pleura though it spares the lung parenchyma." }, "child_count": 0, "reference_id": "MONDO:0006094" }, { "id": 7835, "label": "pleural cancer", "isLeaf": false, "isRoot": false, "parents": [ 2875, 5215, 20306 ], "type_id": 0, "properties": { "xrefs": [ "DOID:5158", "EFO:1000362", "ICD10CM:C38.4", "ICD9:163", "ICD9:163.8", "ICD9:163.9", "MEDGEN:56307", "NCIT:C3547", "SCTID:363433009", "UMLS:C0153494" ], "synonyms": [ "neoplasm of pleura", "pleural tumor", "pleural tumour", "cancer of pleura", "cancer of the pleura", "malignant neoplasm of pleura", "malignant neoplasm of the pleura", "malignant pleura neoplasm", "malignant pleural neoplasm", "malignant pleural tumor", "malignant pleural tumour", "malignant tumor of pleura", "malignant tumor of the pleura", "malignant tumour of pleura", "malignant tumour of the pleura", "pleura cancer", "pleural cancer" ], "categories": [ { "ref": "MONDO:0005087", "name": "respiratory system disorder" } ], "definition": "A primary or metastatic malignant neoplasm affecting the pleura. A representative example of primary malignant pleural neoplasm is the malignant pleural mesothelioma. A representative example of metastatic malignant neoplasm to the pleura is metastatic carcinoma that has spread to the pleura from another anatomic site." }, "child_count": 12, "reference_id": "MONDO:0006294" }, { "id": 8659, "label": "breast cancer", "isLeaf": false, "isRoot": false, "parents": [ 5215, 20340 ], "type_id": 0, "properties": { "xrefs": [ "DOID:1612", "ICD10CM:C50", "ICD9:174.8", "MEDGEN:651", "NCIT:C9335", "SCTID:254837009", "UMLS:C0006142", "icd11.foundation:1047754165" ], "synonyms": [ "breast tumor", "breast tumour", "mammary tumor", "mammary tumour", "breast cancer", "cancer of breast", "malignant breast neoplasm", "malignant breast tumor", "malignant breast tumour", "malignant neoplasm of breast", "malignant neoplasm of the breast", "malignant tumor of breast", "malignant tumor of the breast", "malignant tumour of breast", "malignant tumour of the breast", "primary breast cancer" ], "categories": [ { "ref": "MONDO:0002657", "name": "breast disorder" } ], "definition": "A primary or metastatic malignant neoplasm involving the breast. The vast majority of cases are carcinomas arising from the breast parenchyma or the nipple. Malignant breast neoplasms occur more frequently in females than in males." }, "child_count": 12, "reference_id": "MONDO:0007254" }, { "id": 10167, "label": "lung cancer", "isLeaf": false, "isRoot": false, "parents": [ 2875, 5215, 20356 ], "type_id": 0, "properties": { "xrefs": [ "DOID:1324", "ICD9:162.3", "ICD9:162.4", "ICD9:162.5", "ICD9:162.8", "ICD9:162.9", "MEDGEN:66885", "NCIT:C7377", "OMIM:211980", "SCTID:363358000", "UMLS:C0242379" ], "synonyms": [ "adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "adenocarcinoma of lung, somatic", "cancer of lung", "lung cancer", "lung cancer, protection against, autosomal dominant, somatic mutation", "lung cancer, resistance to, autosomal dominant, somatic mutation", "lung cancer, somatic", "lung cancer, susceptibility to, autosomal dominant, somatic mutation", "malignant lung neoplasm", "malignant lung tumor", "malignant lung tumour", "malignant neoplasm of lung", "malignant neoplasm of the lung", "malignant tumor of lung", "malignant tumor of the lung", "malignant tumour of lung", "malignant tumour of the lung", "nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "nonsmall cell lung cancer, somatic", "nonsmall cell lung cancer, susceptibility to, autosomal dominant, somatic mutation", "Nonsmall cell lung cancer", "alveolar cell carcinoma", "lung cancer, protection against" ], "categories": [ { "ref": "MONDO:0005087", "name": "respiratory system disorder" } ], "definition": "A malignant neoplasm involving the lung." }, "child_count": 21, "reference_id": "MONDO:0008903" }, { "id": 20502, "label": "malignant neoplasm of chest wall", "isLeaf": false, "isRoot": false, "parents": [ 5215, 20543 ], "type_id": 0, "properties": { "xrefs": [ "MEDGEN:138070", "NCIT:C4580", "SCTID:712750007", "UMLS:C0346948" ], "synonyms": [ "cancer of chest wall", "chest wall cancer", "malignant chest wall neoplasm", "malignant chest wall tumor", "malignant chest wall tumour", "malignant neoplasm of chest wall", "malignant neoplasm of the chest wall", "malignant tumor of chest wall", "malignant tumor of the chest wall", "malignant tumour of chest wall", "malignant tumour of the chest wall" ], "definition": "A cancer that involves the chest wall." }, "child_count": 4, "reference_id": "MONDO:0021323" } ], "roots": [ { "id": 6733, "label": "cancer" }, { "id": 20518, "label": "neoplasm of thorax" } ] }