{
  "id": 5272,
  "label": "demyelinating polyneuropathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003334",
  "properties": {
    "xrefs": [
      "DOID:5214",
      "GARD:0023456",
      "ICD9:356.9",
      "MEDGEN:82859",
      "NCIT:C27062",
      "SCTID:23414001",
      "UMLS:C0270922"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Polyneuropathy that is characterized by demyelination of axons."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 4005,
      "label": "polyneuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6950
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1389",
          "EFO:0009562",
          "ICD9:356.9",
          "ICD9:357.4",
          "MEDGEN:57502",
          "MESH:D011115",
          "NCIT:C26951",
          "SCTID:42345000",
          "UMLS:C0152025",
          "icd11.foundation:58868923"
        ],
        "synonyms": [
          "polyneuropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disease or disorder affecting more than one nerve."
      },
      "child_count": 10,
      "reference_id": "MONDO:0001824"
    },
    {
      "id": 4626,
      "label": "demyelinating disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7208,
        20383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3213",
          "MEDGEN:4189",
          "MESH:D003711",
          "NCIT:C34527",
          "UMLS:C0011303"
        ],
        "synonyms": [
          "demyelinating disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A broad group of disorders that affect the myelin sheaths that cover the neurons. Myelin sheathes cover neuronal axons in the central and peripheral nervous system and function to increase traveling impulse speeds. Disruption of this sheath impairs neuronal transmission and can result in disorders such as multiple sclerosis and Guillain-Barre syndrome, among others."
      },
      "child_count": 16,
      "reference_id": "MONDO:0002562"
    }
  ],
  "children": [
    {
      "id": 8165,
      "label": "chronic inflammatory demyelinating polyradiculoneuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5272,
        5273,
        8348,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5213",
          "EFO:1000868",
          "GARD:0006102",
          "ICD10CM:G61.81",
          "ICD9:357.81",
          "ICD9:357.89",
          "MEDGEN:98292",
          "MESH:D020277",
          "MedDRA:10057645",
          "NANDO:1200030",
          "NANDO:2100251",
          "NANDO:2200905",
          "NCIT:C84636",
          "Orphanet:2932",
          "SCTID:128209004",
          "UMLS:C0393819",
          "icd11.foundation:224318510"
        ],
        "synonyms": [
          "CIDP",
          "chronic inflammatory demyelinating polyneuropathy",
          "chronic inflammatory demyelinating polyradiculoneuropathy",
          "chronic relapsing polyneuropathy",
          "chronic inflammatory demyelinating polyneuritis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare neurological disorder in which there is inflammation of nerve roots and peripheral nerves and destruction of the fatty protective covering (myelin sheath) over the nerves. This affects how fast the nerve signals are transmitted and leads to loss of nerve fibers. This causes weakness, paralysis and/or impairment in motor function, especially of the arms and legs (limbs). Sensory disturbance may also be present. The motor and sensory impairments usually affect both sides of the body (symmetrical), and the degree of severity and the course of disease may vary from case to case. Some affected individuals may follow a slow steady pattern of symptoms while others may have symptoms that stabilize and then relapse."
      },
      "child_count": 4,
      "reference_id": "MONDO:0006702"
    },
    {
      "id": 16729,
      "label": "subacute inflammatory demyelinating polyneuropathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5272,
        20092
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020355",
          "MEDGEN:629329",
          "Orphanet:206594",
          "SCTID:277189006",
          "UMLS:C0456517",
          "icd11.foundation:1692167541"
        ],
        "synonyms": [
          "SIDP",
          "subacute inflammatory demyelinating polyradiculoneuropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A subacute progressive symmetric sensorial and/or motor disorder characterized by muscular weakness with impaired sensation, absent or diminished tendon reflexes and elevated cerebrospinal fluid (CSF) proteins. SIDP is an intermediate form between Guillain-Barre syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016102"
    }
  ],
  "roots": [
    {
      "id": 4005,
      "label": "polyneuropathy"
    },
    {
      "id": 4626,
      "label": "demyelinating disease"
    }
  ]
}