{
  "id": 5284,
  "label": "central nervous system leiomyosarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003349",
  "properties": {
    "xrefs": [
      "DOID:5254",
      "GARD:0023465",
      "MEDGEN:235254",
      "NCIT:C6999",
      "UMLS:C1334385"
    ],
    "synonyms": [
      "CNS leiomyosarcoma",
      "central nervous system leiomyosarcoma",
      "leiomyosarcoma of CNS",
      "leiomyosarcoma of central nervous system",
      "leiomyosarcoma of the CNS",
      "leiomyosarcoma of the central nervous system"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "An aggressive malignant smooth muscle neoplasm, arising from the central nervous system. It is characterized by a proliferation of neoplastic spindle cells."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 4336,
      "label": "central nervous system sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4753,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2133",
          "GARD:0023088",
          "MEDGEN:272444",
          "NCIT:C5153",
          "UMLS:C1332892"
        ],
        "synonyms": [
          "CNS sarcoma",
          "central nervous system sarcoma",
          "sarcoma of CNS",
          "sarcoma of central nervous system",
          "sarcoma of the CNS",
          "sarcoma of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A sarcoma that arises from the central nervous system."
      },
      "child_count": 24,
      "reference_id": "MONDO:0002217"
    },
    {
      "id": 6788,
      "label": "leiomyosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4931,
        17662,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1967",
          "EFO:0000564",
          "GARD:0006880",
          "ICD9:171.9",
          "ICDO:8890/3",
          "MEDGEN:9711",
          "MESH:D007890",
          "MedDRA:10024189",
          "NANDO:2200064",
          "NCIT:C3158",
          "NORD:1356",
          "ONCOTREE:LMS",
          "Orphanet:64720",
          "SCTID:443719001",
          "UMLS:C0023269"
        ],
        "synonyms": [
          "Leiomyosarcomas",
          "leiomyosarcoma",
          "leiomyosarcoma (excluding uterine leiomyosarcoma)",
          "leiomyosarcoma - not uterine",
          "leiomyosarcoma, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "An uncommon, aggressive malignant smooth muscle neoplasm, usually occurring in post-menopausal women. It is characterized by a proliferation of neoplastic spindle cells. Morphologic variants include epithelioid, granular cell, inflammatory and myxoid leimyosarcomas."
      },
      "child_count": 93,
      "reference_id": "MONDO:0005058"
    },
    {
      "id": 22971,
      "label": "malignant central nervous system mesenchymal, non-meningothelial neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4753,
        5190,
        21548
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027956",
          "MEDGEN:233147",
          "NCIT:C6758",
          "UMLS:C1334571"
        ],
        "synonyms": [
          "central nervous system mesenchymal non-meningothelial tumor, malignant",
          "malignant CNS soft tissue neoplasm",
          "malignant CNS soft tissue tumor",
          "malignant CNS soft tissue tumour",
          "malignant central nervous system mesenchymal non-meningothelial tumor",
          "malignant central nervous system mesenchymal non-meningothelial tumour",
          "malignant central nervous system mesenchymal, non-meningothelial neoplasm",
          "malignant central nervous system mesenchymal, non-meningothelial tumor",
          "malignant central nervous system mesenchymal, non-meningothelial tumour",
          "malignant central nervous system soft tissue neoplasm",
          "malignant central nervous system soft tissue tumor",
          "malignant central nervous system soft tissue tumour",
          "malignant soft tissue neoplasm of CNS",
          "malignant soft tissue neoplasm of central nervous system",
          "malignant soft tissue neoplasm of the CNS",
          "malignant soft tissue neoplasm of the central nervous system",
          "malignant soft tissue tumor of CNS",
          "malignant soft tissue tumor of central nervous system",
          "malignant soft tissue tumor of the CNS",
          "malignant soft tissue tumor of the central nervous system",
          "malignant soft tissue tumour of CNS",
          "malignant soft tissue tumour of central nervous system",
          "malignant soft tissue tumour of the CNS",
          "malignant soft tissue tumour of the central nervous system",
          "soft tissue cancer of central nervous system",
          "soft tissue cancer of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A metastasizing mesenchymal, non-meningothelial neoplasm that arises from the central nervous system."
      },
      "child_count": 9,
      "reference_id": "MONDO:0037740"
    }
  ],
  "children": [
    {
      "id": 5285,
      "label": "granular cell leiomyosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5197,
        5284
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5258",
          "GARD:0023466",
          "MEDGEN:234321",
          "NCIT:C27494",
          "UMLS:C1333871"
        ],
        "synonyms": [
          "granular cell leiomyosarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An aggressive malignant smooth muscle neoplasm. It is characterized by the presence of malignant smooth muscle cells with granular cytoplasmic changes."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003350"
    }
  ],
  "roots": [
    {
      "id": 4336,
      "label": "central nervous system sarcoma"
    },
    {
      "id": 6788,
      "label": "leiomyosarcoma"
    },
    {
      "id": 22971,
      "label": "malignant central nervous system mesenchymal, non-meningothelial neoplasm"
    }
  ]
}