{
  "id": 5318,
  "label": "bladder clear cell adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003386",
  "properties": {
    "xrefs": [
      "DOID:5306",
      "MEDGEN:272370",
      "NCIT:C6179",
      "UMLS:C1332557"
    ],
    "synonyms": [
      "bladder clear cell adenocarcinoma",
      "urinary bladder clear cell adenocarcinoma",
      "clear cell adenocarcinoma of the bladder",
      "clear cell adenocarcinoma of the urinary bladder",
      "clear cell adenocarcinoma of urinary bladder"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "A rare morphologic variant of bladder adenocarcinoma characterized by the presence of malignant glandular epithelial cells and clear cells distributed in a tubulo-cystic, papillary, or diffuse pattern. There is a female predilection. Clinical presentation includes hematuria and dysuria."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4786,
      "label": "bladder adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712,
        6727
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3711",
          "EFO:1000125",
          "MEDGEN:76014",
          "NCIT:C4032",
          "ONCOTREE:BLAD",
          "SCTID:255110003",
          "UMLS:C0279682"
        ],
        "synonyms": [
          "adenocarcinoma of bladder",
          "adenocarcinoma of the bladder",
          "adenocarcinoma of the urinary bladder",
          "adenocarcinoma of urinary bladder",
          "bladder adenocarcinoma",
          "urinary bladder adenocarcinoma",
          "blad"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A carcinoma that arises from glandular epithelial cells of the urinary bladder"
      },
      "child_count": 14,
      "reference_id": "MONDO:0002751"
    },
    {
      "id": 6742,
      "label": "clear cell adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4468",
          "EFO:0000348",
          "ICDO:8310/3",
          "MEDGEN:64629",
          "MESH:D018262",
          "NCIT:C3766",
          "UMLS:C0206681"
        ],
        "synonyms": [
          "adenocarcinoma, clear cell, malignant",
          "clear cell adenocarcinoma",
          "clear cell adenocarcinoma (morphologic abnormality)",
          "clear cell adenocarcinoma NOS (morphologic abnormality)",
          "mesonephroma NOS (morphologic abnormality)",
          "water-clear cell adenocarcinoma (morphologic abnormality)",
          "Wolffian duct neoplasm",
          "clear cell carcinoma",
          "malignant mesonephroma",
          "mesonephroid clear cell adenocarcinoma",
          "mesonephroid clear cell carcinoma",
          "mesonephroma, malignant",
          "mesonephroma, malignant (morphologic abnormality)",
          "water-clear cell carcinoma"
        ],
        "definition": "A malignant neoplasm composed of glandular epithelial clear cells. Various architectural patterns may be seen, including papillary, tubulocystic, and solid."
      },
      "child_count": 11,
      "reference_id": "MONDO:0005004"
    }
  ],
  "children": [
    {
      "id": 5683,
      "label": "bladder diffuse clear cell adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5318
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6210",
          "MEDGEN:267058",
          "NCIT:C39849",
          "UMLS:C1511187"
        ],
        "synonyms": [
          "bladder diffuse clear cell adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A rare morphologic variant of bladder adenocarcinoma characterized by the presence of malignant glandular epithelial cells and clear cells forming a diffuse pattern."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003810"
    },
    {
      "id": 6250,
      "label": "bladder tubulo-cystic clear cell adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5318
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8050",
          "MEDGEN:267060",
          "NCIT:C39847",
          "UMLS:C1511203"
        ],
        "synonyms": [
          "bladder tubulo-cystic clear cell adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A rare morphologic variant of bladder carcinoma characterized by the presence of malignant glandular epithelial cells and clear cells forming a tubulo-cystic pattern."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004444"
    },
    {
      "id": 6251,
      "label": "bladder papillary clear cell adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5318
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8051",
          "MEDGEN:307286",
          "NCIT:C39848",
          "UMLS:C1511196"
        ],
        "synonyms": [
          "bladder papillary clear cell adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A rare morphologic variant of bladder adenocarcinoma characterized by the presence of malignant glandular epithelial cells and clear cells forming a papillary pattern."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004445"
    }
  ],
  "roots": [
    {
      "id": 4786,
      "label": "bladder adenocarcinoma"
    },
    {
      "id": 6742,
      "label": "clear cell adenocarcinoma"
    }
  ]
}