{
  "id": 5320,
  "label": "ampulla of vater clear cell adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003388",
  "properties": {
    "xrefs": [
      "DOID:5308",
      "GARD:0023494",
      "MEDGEN:233972",
      "NCIT:C27414",
      "UMLS:C1332246"
    ],
    "synonyms": [
      "ampulla of Vater clear cell adenocarcinoma",
      "hepatopancreatic ampulla clear cell adenocarcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A carcinoma with glandular differentiation arising from the ampulla of Vater. Morphologically, it is characterized by the presence of glycogen-rich cells with hyperchromatic nuclei."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4718,
      "label": "ampulla of vater adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4714,
        7742,
        17870
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3502",
          "EFO:0008490",
          "GARD:0023208",
          "MEDGEN:231054",
          "NCIT:C6650",
          "UMLS:C1332243",
          "icd11.foundation:1601321941"
        ],
        "synonyms": [
          "adenocarcinoma of ampulla of Vater",
          "ampulla of Vater adenocarcinoma",
          "ampullary adenocarcinoma",
          "hepatopancreatic ampulla adenocarcinoma",
          "invasive adenocarcinoma of the ampullary region"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A carcinoma that arises from glandular epithelial cells of the hepatopancreatic ampulla"
      },
      "child_count": 12,
      "reference_id": "MONDO:0002670"
    },
    {
      "id": 5917,
      "label": "extrahepatic bile duct clear cell adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4714,
        6742
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7032",
          "GARD:0023808",
          "MEDGEN:167829",
          "NCIT:C5775",
          "UMLS:C0861855"
        ],
        "synonyms": [
          "bile duct clear cell adenocarcinoma",
          "clear cell adenocarcinoma of bile duct",
          "clear cell adenocarcinoma of the bile duct",
          "clear cell bile duct adenocarcinoma",
          "extrahepatic bile duct clear cell adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A morphologic variant of extrahepatic bile duct adenocarcinoma characterized by the presence of malignant glandular epithelium composed of clear cells."
      },
      "child_count": 2,
      "reference_id": "MONDO:0004081"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4718,
      "label": "ampulla of vater adenocarcinoma"
    },
    {
      "id": 5917,
      "label": "extrahepatic bile duct clear cell adenocarcinoma"
    }
  ]
}