{
  "id": 5321,
  "label": "epithelial-myoepithelial carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003389",
  "properties": {
    "xrefs": [
      "DOID:5309",
      "GARD:0027639",
      "ICDO:8562/3",
      "MEDGEN:90776",
      "NCIT:C4199",
      "ONCOTREE:EMYOCA",
      "UMLS:C0334392"
    ],
    "synonyms": [
      "epithelial-myoepithelial carcinoma",
      "EMYOCA"
    ],
    "definition": "A malignant neoplasm which occurs mostly in the major salivary glands (most frequently in the parotid gland), but also in the minor salivary glands of the oral mucosa and the tracheobronchial tree. It is characterized by the presence of ductal structures which are lined by an inner layer of cuboidal epithelial-type cells and an outer layer of myoepithelial cells with clear or eosinophilic cytoplasm."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6734,
      "label": "carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-1867",
          "DOID:305",
          "EFO:0000313",
          "ICDO:8010/3",
          "ICDO:8011/3",
          "MEDGEN:2867",
          "MESH:D002277",
          "NCIT:C2916",
          "SCTID:722688002",
          "UMLS:C0007097"
        ],
        "synonyms": [
          "epithelioma",
          "Other carcinoma",
          "carcinoma",
          "carcinoma, malignant",
          "epithelial carcinoma",
          "epithelioma malignant",
          "malignant epithelial neoplasm",
          "malignant epithelial tumor",
          "malignant epithelial tumour",
          "malignant epithelioma"
        ],
        "definition": "A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas."
      },
      "child_count": 98,
      "reference_id": "MONDO:0004993"
    }
  ],
  "children": [
    {
      "id": 20102,
      "label": "salivary gland epithelial myoepithelial carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2972,
        5321
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027873",
          "MEDGEN:234769",
          "NCIT:C35701",
          "UMLS:C1335900"
        ],
        "synonyms": [
          "salivary gland epithelial myoepithelial carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A carcinoma that arises from the salivary glands, most often the parotid gland. It presents as a slow growing and painless mass. It is characterized by the presence of duct-like structures lined by two layers of cells, an inner layer composed of epithelial-type cells and an outer layer composed of clear, myoepithelial-type cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020694"
    },
    {
      "id": 20105,
      "label": "lung epithelial-myoepithelial carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5321,
        6862
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027874",
          "MEDGEN:353868",
          "NCIT:C45545",
          "UMLS:C1708770"
        ],
        "synonyms": [
          "lung epithelial-myoepithelial cancer",
          "lung epithelial-myoepithelial carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A lung carcinoma arising within the bronchi or bronchial tubes. It is characterized by the presence of myoepithelial cells, spindle cells, clear cells, and duct-forming epithelial cells. Surgical resection may be curative."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020697"
    }
  ],
  "roots": [
    {
      "id": 6734,
      "label": "carcinoma"
    }
  ]
}