{
  "id": 5333,
  "label": "central nervous system endodermal sinus tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003401",
  "properties": {
    "xrefs": [
      "DOID:5343",
      "GARD:0023501",
      "MEDGEN:234604",
      "NCIT:C6209",
      "UMLS:C1377613"
    ],
    "synonyms": [
      "central nervous system yolk Sac tumor",
      "central nervous system yolk Sac tumour",
      "central nervous system yolk sac tumor",
      "central nervous system yolk sac tumour",
      "childhood central nervous system yolk Sac neoplasm",
      "childhood central nervous system yolk Sac tumor",
      "childhood central nervous system yolk Sac tumour",
      "paediatric central nervous system yolk Sac neoplasm",
      "paediatric central nervous system yolk Sac tumour",
      "pediatric central nervous system yolk Sac neoplasm",
      "pediatric central nervous system yolk Sac tumor",
      "yolk Sac tumor of the CNS",
      "yolk Sac tumour of the CNS",
      "central nervous system endodermal sinus tumor",
      "childhood central nervous system endodermal sinus neoplasm",
      "childhood central nervous system endodermal sinus tumor",
      "childhood central nervous system endodermal sinus tumour",
      "paediatric central nervous system endodermal sinus neoplasm",
      "pediatric central nervous system endodermal sinus neoplasm"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A yolk sac tumor that arises from the central nervous system and occurs during childhood."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 4753,
      "label": "central nervous system cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7479,
        7694
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3620",
          "EFO:0000326",
          "GARD:0027614",
          "ICD9:239.7",
          "MEDGEN:87593",
          "MESH:D016543",
          "NANDO:2100007",
          "NCIT:C4627",
          "SCTID:126951006",
          "UMLS:C0348374"
        ],
        "synonyms": [
          "CNS neoplasm",
          "central nervous system tumor",
          "central nervous system tumour",
          "CNS cancer",
          "CNS malignant neoplasms",
          "CNS neoplasms, malignant",
          "cancer of CNS",
          "cancer of central nervous system",
          "cancer of the CNS",
          "cancer of the central nervous system",
          "central nervous system cancer",
          "central nervous system neoplasms, malignant",
          "central nervous system tumours",
          "malignant CNS neoplasm",
          "malignant CNS neoplasms",
          "malignant CNS tumor",
          "malignant CNS tumour",
          "malignant central nervous system neoplasm",
          "malignant central nervous system tumor",
          "malignant central nervous system tumour",
          "malignant neoplasm of CNS",
          "malignant neoplasm of central nervous system",
          "malignant neoplasm of the CNS",
          "malignant neoplasm of the central nervous system",
          "malignant tumor of CNS",
          "malignant tumor of central nervous system",
          "malignant tumor of the CNS",
          "malignant tumor of the central nervous system",
          "malignant tumour of CNS",
          "malignant tumour of central nervous system",
          "malignant tumour of the CNS",
          "malignant tumour of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the central nervous system"
      },
      "child_count": 40,
      "reference_id": "MONDO:0002714"
    },
    {
      "id": 5332,
      "label": "childhood endodermal sinus tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6283,
        7365
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5342",
          "GARD:0023500",
          "MEDGEN:234139",
          "NCIT:C27364",
          "UMLS:C1333016"
        ],
        "synonyms": [
          "childhood endodermal sinus neoplasm",
          "childhood endodermal sinus tumor",
          "pediatric yolk Sac tumor",
          "childhood yolk Sac neoplasm",
          "childhood yolk Sac tumor",
          "childhood yolk Sac tumour",
          "paediatric endodermal sinus neoplasm",
          "paediatric yolk Sac neoplasm",
          "pediatric endodermal sinus neoplasm",
          "pediatric yolk Sac neoplasm"
        ],
        "definition": "A yolk sac tumor that occurs during childhood."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003400"
    },
    {
      "id": 5630,
      "label": "childhood central nervous system germ cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4999,
        5631
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6052",
          "GARD:0023650",
          "MEDGEN:124505",
          "NCIT:C6205",
          "UMLS:C0278754"
        ],
        "synonyms": [
          "central nervous system germ cell tumor",
          "central nervous system germ cell tumour",
          "central nervous system childhood germ cell tumor",
          "central nervous system paediatric germ cell cancer",
          "central nervous system pediatric germ cell cancer",
          "childhood CNS germ cell neoplasm",
          "childhood CNS germ cell tumor",
          "childhood CNS germ cell tumour",
          "childhood central nervous system germ cell neoplasm",
          "childhood central nervous system germ cell tumor",
          "childhood germ cell neoplasm of CNS",
          "childhood germ cell neoplasm of central nervous system",
          "childhood germ cell neoplasm of the CNS",
          "childhood germ cell neoplasm of the central nervous system",
          "childhood germ cell tumor of CNS",
          "childhood germ cell tumor of central nervous system",
          "childhood germ cell tumor of the CNS",
          "childhood germ cell tumor of the central nervous system",
          "childhood germ cell tumour of CNS",
          "childhood germ cell tumour of central nervous system",
          "childhood germ cell tumour of the CNS",
          "childhood germ cell tumour of the central nervous system",
          "paediatric CNS germ cell neoplasm",
          "paediatric CNS germ cell tumour",
          "paediatric central nervous system germ cell neoplasm",
          "paediatric central nervous system germ cell tumour",
          "paediatric germ cell neoplasm of central nervous system",
          "paediatric germ cell neoplasm of the CNS",
          "paediatric germ cell neoplasm of the central nervous system",
          "paediatric germ cell tumour of CNS",
          "paediatric germ cell tumour of central nervous system",
          "paediatric germ cell tumour of the CNS",
          "paediatric germ cell tumour of the central nervous system",
          "pediatric CNS germ cell neoplasm",
          "pediatric CNS germ cell tumor",
          "pediatric central nervous system germ cell neoplasm",
          "pediatric central nervous system germ cell tumor",
          "pediatric germ cell neoplasm of CNS",
          "pediatric germ cell neoplasm of central nervous system",
          "pediatric germ cell neoplasm of the CNS",
          "pediatric germ cell neoplasm of the central nervous system",
          "pediatric germ cell tumor of CNS",
          "pediatric germ cell tumor of central nervous system",
          "pediatric germ cell tumor of the CNS",
          "pediatric germ cell tumor of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A germ cell tumor of the central nervous system occurring in children."
      },
      "child_count": 16,
      "reference_id": "MONDO:0003750"
    },
    {
      "id": 17189,
      "label": "yolk sac tumor of central nervous system",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7365
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020733",
          "MEDGEN:234492",
          "NCIT:C7011",
          "Orphanet:252006",
          "UMLS:C1337040",
          "icd11.foundation:1023155823"
        ],
        "synonyms": [
          "CNS yolk Sac tumor",
          "CNS yolk Sac tumour",
          "central nervous system yolk Sac tumor",
          "central nervous system yolk Sac tumour",
          "endodermal sinus tumor of CNS",
          "endodermal sinus tumor of central nervous system",
          "endodermal sinus tumour of CNS",
          "endodermal sinus tumour of central nervous system",
          "intracranial endodermal sinus tumor",
          "intracranial endodermal sinus tumour",
          "intracranial yolk sac tumor",
          "intracranial yolk sac tumour",
          "yolk Sac tumor of CNS",
          "yolk Sac tumor of central nervous system",
          "yolk Sac tumor of the CNS",
          "yolk Sac tumor of the central nervous system",
          "yolk Sac tumour of CNS",
          "yolk Sac tumour of central nervous system",
          "yolk Sac tumour of the CNS",
          "yolk Sac tumour of the central nervous system",
          "yolk sac tumor of CNS",
          "yolk sac tumour of CNS"
        ],
        "definition": "A malignant germ cell tumor of the central nervous system composed of primitive-appearing epithelial cells - putatively representing yolk sac endoderm - set in a loose, variably cellular, and often conspicuously myxoid matrix, resembling extra-embryonic mesoblast. Eosinophilic hyaline globules immunoreactive for AFP are a diagnostic feature. (WHO)"
      },
      "child_count": 1,
      "reference_id": "MONDO:0016739"
    },
    {
      "id": 20012,
      "label": "central nervous system nongerminomatous germ cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4999,
        19983
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025171",
          "MEDGEN:760465",
          "NCIT:C100093",
          "UMLS:C1696109"
        ],
        "synonyms": [
          "central nervous system nongerminomatous germ cell tumor",
          "nongerminomatous GCT - CNS",
          "nongerminomatous germ cell tumor of the CNS",
          "nongerminomatous germ cell tumour of the CNS"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Germ cell tumors of the central nervous system other than germinoma. This category includes teratoma, choriocarcinoma, embryonal carcinoma, and yolk sac tumor."
      },
      "child_count": 8,
      "reference_id": "MONDO:0020574"
    }
  ],
  "children": [
    {
      "id": 5331,
      "label": "pineal region yolk sac tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4216,
        5333
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5341",
          "GARD:0023499",
          "MEDGEN:277518",
          "NCIT:C6752",
          "UMLS:C1335420"
        ],
        "synonyms": [
          "pineal body yolk sac tumor",
          "pineal body yolk sac tumour",
          "pineal region yolk Sac neoplasm",
          "pineal region yolk sac tumor",
          "endodermal sinus tumor of pineal region",
          "endodermal sinus tumor of the pineal region",
          "endodermal sinus tumour of pineal region",
          "endodermal sinus tumour of the pineal region",
          "pineal endodermal sinus neoplasm",
          "pineal endodermal sinus tumor",
          "pineal endodermal sinus tumour",
          "pineal region endodermal sinus neoplasm",
          "pineal region endodermal sinus tumor",
          "pineal region endodermal sinus tumour",
          "yolk Sac tumor of pineal region",
          "yolk Sac tumor of the pineal region",
          "yolk Sac tumour of pineal region",
          "yolk Sac tumour of the pineal region"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A yolk sac tumor that involves the pineal body."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003399"
    }
  ],
  "roots": [
    {
      "id": 4753,
      "label": "central nervous system cancer"
    },
    {
      "id": 5332,
      "label": "childhood endodermal sinus tumor"
    },
    {
      "id": 5630,
      "label": "childhood central nervous system germ cell tumor"
    },
    {
      "id": 17189,
      "label": "yolk sac tumor of central nervous system"
    },
    {
      "id": 20012,
      "label": "central nervous system nongerminomatous germ cell tumor"
    }
  ]
}