{
  "id": 5353,
  "label": "ophthalmoplegia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003425",
  "properties": {
    "xrefs": [
      "DOID:539",
      "ICD9:378.56",
      "MEDGEN:45205",
      "MESH:D009886",
      "SCTID:78097002",
      "UMLS:C0029089",
      "icd11.foundation:1848588735"
    ],
    "synonyms": [
      "oculomotor paralysis"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Weakness or paralysis of at least one of the muscles controlling the movement of the eye. It results from degeneration of the muscles or the neural pathways involved in the eye movement. Representative disorders causing ophthalmoplegia include ocular myopathies and multiple sclerosis."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 3785,
      "label": "ocular motility disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5469
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1279",
          "EFO:1001990",
          "ICD9:378.9",
          "MEDGEN:14457",
          "SCTID:45030009",
          "UMLS:C0028850"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 6,
      "reference_id": "MONDO:0001584"
    },
    {
      "id": 7990,
      "label": "palsy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4657
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000631",
          "ICD10CM:G80-G83",
          "MEDGEN:854494",
          "MESH:D010243",
          "UMLS:C3887651",
          "Wikipedia:Palsy"
        ],
        "synonyms": [
          "Plegia",
          "Plegias"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)"
      },
      "child_count": 10,
      "reference_id": "MONDO:0006496"
    }
  ],
  "children": [
    {
      "id": 3839,
      "label": "exophthalmic ophthalmoplegia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3717,
        4015,
        5353
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13135",
          "ICD9:376.22",
          "MEDGEN:508900",
          "SCTID:69763009",
          "UMLS:C0152135"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001643"
    },
    {
      "id": 5346,
      "label": "internuclear ophthalmoplegia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5353,
        5360
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:538",
          "ICD10CM:H51.2",
          "ICD9:378.86",
          "MEDGEN:101820",
          "SCTID:49823009",
          "UMLS:C0152134",
          "icd11.foundation:377040542"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0003417"
    },
    {
      "id": 6902,
      "label": "progressive external ophthalmoplegia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4427,
        5353,
        10856,
        24270
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12558",
          "EFO:0002509",
          "GARD:0004503",
          "HP:0000590",
          "ICD10CM:H49.4",
          "ICD9:378.72",
          "MEDGEN:102439",
          "MESH:D017246",
          "NANDO:1200174",
          "Orphanet:520820",
          "SCTID:46252003",
          "UMLS:C0162674",
          "icd11.foundation:1698427219"
        ],
        "synonyms": [
          "chronic progressive external ophthalmoplegia [ambiguous]",
          "progressive external ophthalmoplegia",
          "chronic progressive external ophthalmoplegia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A mitochondrial myopathy characterized by slowly progressive paralysis of the levator palpebrae, orbicularis oculi, and extraocular muscles. Ragged-red fibers and atrophy are found on muscle biopsy. Familial and sporadic forms may occur. Disease onset is usually in the first or second decade of life, and the illness slowly progresses until usually all ocular motility is lost. (From Adams et al., Principles of Neurology, 6th ed, p1422)"
      },
      "child_count": 12,
      "reference_id": "MONDO:0005181"
    }
  ],
  "roots": [
    {
      "id": 3785,
      "label": "ocular motility disease"
    },
    {
      "id": 7990,
      "label": "palsy"
    }
  ]
}