{
  "id": 5358,
  "label": "prolactin producing pituitary tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003430",
  "properties": {
    "xrefs": [
      "DOID:5396",
      "GARD:0023508",
      "MEDGEN:82998",
      "NCIT:C7910",
      "UMLS:C0278863"
    ],
    "synonyms": [
      "PRL producing pituitary gland neoplasm",
      "prolactin producing neoplasm of pituitary",
      "prolactin producing neoplasm of pituitary gland",
      "prolactin producing neoplasm of the pituitary",
      "prolactin producing neoplasm of the pituitary gland",
      "prolactin producing pituitary gland neoplasm",
      "prolactin producing pituitary gland tumor",
      "prolactin producing pituitary gland tumour",
      "prolactin producing pituitary neoplasm",
      "prolactin producing tumor of pituitary",
      "prolactin producing tumor of pituitary gland",
      "prolactin producing tumor of the pituitary",
      "prolactin producing tumor of the pituitary gland",
      "prolactin producing tumour of pituitary",
      "prolactin producing tumour of pituitary gland",
      "prolactin producing tumour of the pituitary",
      "prolactin producing tumour of the pituitary gland",
      "prolactin secreting neoplasm of pituitary",
      "prolactin secreting neoplasm of pituitary gland",
      "prolactin secreting neoplasm of the pituitary",
      "prolactin secreting neoplasm of the pituitary gland",
      "prolactin secreting pituitary gland neoplasm",
      "prolactin secreting pituitary gland tumor",
      "prolactin secreting pituitary gland tumour",
      "prolactin secreting pituitary neoplasm",
      "prolactin secreting pituitary tumor",
      "prolactin secreting pituitary tumour",
      "prolactin secreting tumor of pituitary gland",
      "prolactin secreting tumor of the pituitary",
      "prolactin secreting tumor of the pituitary gland",
      "prolactin secreting tumour of pituitary gland",
      "prolactin secreting tumour of the pituitary",
      "prolactin secreting tumour of the pituitary gland",
      "prolactin-producing pituitary gland neoplasm",
      "prolactin-producing pituitary gland tumor",
      "prolactin-producing pituitary gland tumour",
      "malignant prolactin producing neoplasm of pituitary gland",
      "malignant prolactinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "An adenoma or carcinoma of the anterior lobe of the pituitary gland that produces prolactin."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 17888,
      "label": "pituitary tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4223,
        4759,
        5314,
        7638,
        8247
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021253",
          "ICD9:239.7",
          "MEDGEN:19326",
          "NCIT:C3330",
          "Orphanet:304055",
          "SCTID:127024001",
          "UMLS:C0032019"
        ],
        "synonyms": [
          "neoplasm of pituitary",
          "neoplasm of pituitary gland",
          "neoplasm of the pituitary",
          "neoplasm of the pituitary gland",
          "pituitary gland neoplasm",
          "pituitary gland tumor",
          "pituitary gland tumour",
          "pituitary neoplasm",
          "pituitary tumor",
          "tumor of pituitary",
          "tumor of pituitary gland",
          "tumor of the pituitary",
          "tumor of the pituitary gland",
          "tumour of pituitary",
          "tumour of pituitary gland",
          "tumour of the pituitary",
          "tumour of the pituitary gland"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm affecting the pituitary gland. The vast majority are adenomas arising from the anterior lobe of the pituitary gland."
      },
      "child_count": 45,
      "reference_id": "MONDO:0017611"
    }
  ],
  "children": [
    {
      "id": 7908,
      "label": "prolactin-producing pituitary gland carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5358,
        17862
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000497",
          "GARD:0024393",
          "MEDGEN:277338",
          "NCIT:C5962",
          "UMLS:C1334614"
        ],
        "synonyms": [
          "PRL producing pituitary gland carcinoma",
          "malignant pituitary gland prolactinoma",
          "malignant pituitary prolactinoma",
          "malignant prolactin producing neoplasm of pituitary",
          "malignant prolactin producing neoplasm of pituitary gland",
          "malignant prolactin producing neoplasm of the pituitary",
          "malignant prolactin producing neoplasm of the pituitary gland",
          "malignant prolactin producing pituitary gland neoplasm",
          "malignant prolactin producing pituitary gland tumor",
          "malignant prolactin producing pituitary gland tumour",
          "malignant prolactin producing pituitary neoplasm",
          "malignant prolactin producing pituitary tumor",
          "malignant prolactin producing pituitary tumour",
          "malignant prolactin producing tumor",
          "malignant prolactin producing tumor of pituitary",
          "malignant prolactin producing tumor of pituitary gland",
          "malignant prolactin producing tumor of the pituitary",
          "malignant prolactin producing tumor of the pituitary gland",
          "malignant prolactin producing tumour",
          "malignant prolactin producing tumour of pituitary",
          "malignant prolactin producing tumour of pituitary gland",
          "malignant prolactin producing tumour of the pituitary",
          "malignant prolactin producing tumour of the pituitary gland",
          "malignant prolactin secreting neoplasm of pituitary",
          "malignant prolactin secreting neoplasm of pituitary gland",
          "malignant prolactin secreting neoplasm of the pituitary",
          "malignant prolactin secreting neoplasm of the pituitary gland",
          "malignant prolactin secreting pituitary gland neoplasm",
          "malignant prolactin secreting pituitary gland tumor",
          "malignant prolactin secreting pituitary gland tumour",
          "malignant prolactin secreting pituitary neoplasm",
          "malignant prolactin secreting pituitary tumor",
          "malignant prolactin secreting pituitary tumour",
          "malignant prolactin secreting tumor of pituitary",
          "malignant prolactin secreting tumor of pituitary gland",
          "malignant prolactin secreting tumor of the pituitary",
          "malignant prolactin secreting tumor of the pituitary gland",
          "malignant prolactin secreting tumour of pituitary",
          "malignant prolactin secreting tumour of pituitary gland",
          "malignant prolactin secreting tumour of the pituitary",
          "malignant prolactin secreting tumour of the pituitary gland",
          "malignant prolactinoma",
          "malignant prolactinoma of pituitary",
          "malignant prolactinoma of pituitary gland",
          "malignant prolactinoma of the pituitary",
          "malignant prolactinoma of the pituitary gland",
          "prolactin producing pituitary gland carcinoma",
          "prolactin-producing pituitary gland carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare, hormonally functioning or non-functioning pituitary gland adenocarcinoma that produces prolactin."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006388"
    },
    {
      "id": 12044,
      "label": "prolactin-producing pituitary gland adenoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5358,
        18043
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5394",
          "EFO:1000496",
          "GARD:0004508",
          "ICDO:8271/0",
          "MEDGEN:10936",
          "MESH:D015175",
          "MedDRA:10036832",
          "NANDO:1200378",
          "NCIT:C3342",
          "OMIM:600634",
          "Orphanet:2965",
          "SCTID:134209002",
          "UMLS:C0033375"
        ],
        "synonyms": [
          "PRL producing pituitary gland adenoma",
          "PRL-secreting pituitary adenoma",
          "PRLoma",
          "lactotrope adenoma",
          "lactotroph adenoma",
          "lactotroph cell adenoma",
          "pituitary gland prolactinoma",
          "pituitary lactotrophic adenoma",
          "pituitary prolactinoma",
          "prolactin producing adenoma of pituitary",
          "prolactin producing adenoma of pituitary gland",
          "prolactin producing adenoma of the pituitary",
          "prolactin producing adenoma of the pituitary gland",
          "prolactin producing pituitary adenoma",
          "prolactin producing pituitary gland adenoma",
          "prolactin secreting adenoma",
          "prolactin secreting adenoma of pituitary",
          "prolactin secreting adenoma of pituitary gland",
          "prolactin secreting adenoma of the pituitary",
          "prolactin secreting adenoma of the pituitary gland",
          "prolactin secreting pituitary adenoma",
          "prolactin secreting pituitary gland adenoma",
          "prolactin-producing pituitary gland adenoma",
          "prolactin-secreting pituitary adenoma",
          "prolactinoma",
          "prolactinoma of pituitary",
          "prolactinoma of pituitary gland",
          "prolactinoma of the pituitary",
          "prolactinoma of the pituitary gland",
          "Forbes-Albright syndrome (formerly)",
          "prolactinoma, familial"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Prolactinoma is a usually benign neoplasm of the pituitary gland that results in hyperprolactinemia. The most common clinical manifestations are amenorrhea and infertility in women; and impotence, decreased libido and infertility in men."
      },
      "child_count": 0,
      "reference_id": "MONDO:0010911"
    }
  ],
  "roots": [
    {
      "id": 17888,
      "label": "pituitary tumor"
    }
  ]
}