{
  "id": 5365,
  "label": "combined small cell lung carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003438",
  "properties": {
    "xrefs": [
      "DOID:5421",
      "GARD:0023510",
      "ICDO:8045/3",
      "MEDGEN:234167",
      "NCIT:C9137",
      "ONCOTREE:CSCLC",
      "UMLS:C1333125",
      "icd11.foundation:392248394"
    ],
    "synonyms": [
      "combined small and large cell lung cancer",
      "combined small and large cell lung carcinoma",
      "combined small cell and large cell lung carcinoma",
      "combined small cell carcinoma of lung",
      "combined small cell carcinoma of the lung",
      "combined small cell lung cancer",
      "combined small cell lung carcinoma",
      "combined type small cell carcinoma of lung",
      "combined type small cell carcinoma of the lung",
      "combined type small cell lung carcinoma",
      "mixed small cell and large cell carcinoma of lung",
      "mixed small cell and large cell carcinoma of the lung",
      "mixed small cell and large cell lung carcinoma",
      "small cell and large cell carcinoma of lung",
      "small cell and large cell carcinoma of the lung",
      "small cell and large cell lung carcinoma",
      "CSCLC",
      "lung combined type small cell carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A morphologic variant of small cell lung carcinoma in combination with a non-small cell carcinoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 7728,
      "label": "combined lung carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4255,
        6862,
        7117,
        7464
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000200",
          "GARD:0024316",
          "MEDGEN:234166",
          "NCIT:C7591",
          "UMLS:C1333123"
        ],
        "synonyms": [
          "combined carcinoma of lung",
          "combined carcinoma of the lung",
          "combined lung cancer",
          "combined lung carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A lung carcinoma characterized by the presence of large or small neuroendocrine carcinoma cells in combination with malignant glandular or squamous epithelial cells."
      },
      "child_count": 8,
      "reference_id": "MONDO:0006167"
    },
    {
      "id": 9726,
      "label": "small cell lung carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2894,
        6862,
        7117
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5409",
          "DOID:5411",
          "EFO:0000702",
          "GARD:0009344",
          "ICD9:162.9",
          "MEDGEN:57450",
          "MESH:D055752",
          "NCIT:C4917",
          "OMIM:182280",
          "ONCOTREE:SCLC",
          "Orphanet:70573",
          "SCTID:254632001",
          "UMLS:C0149925",
          "icd11.foundation:1800431439"
        ],
        "synonyms": [
          "SCLC",
          "oat cell carcinoma",
          "oat cell carcinoma (morphologic abnormality)",
          "poorly differentiated endocrine neoplasm",
          "Small cell lung cancer",
          "lung oat cell carcinoma",
          "lung small cell carcinoma",
          "lung small cell neuroendocrine carcinoma",
          "oat cell carcinoma of lung",
          "oat cell carcinoma of the lung",
          "oat cell lung carcinoma",
          "small cell cancer of the lung, somatic",
          "small cell carcinoma of lung",
          "small cell carcinoma of the lung",
          "small cell lung cancer",
          "small cell neuroendocrine carcinoma of lung",
          "small cell neuroendocrine carcinoma of the lung",
          "small-cell cancer of lung",
          "SCLC1",
          "small cell cancer of the lung"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Small cell lung cancer (SCLC) is a highly aggressive malignant neoplasm, accounting for 10-15% of lung cancer cases, characterized byrapid growth, and early metastasis. SCLC usually manifests as a large hilar mass with bulky mediastinal lymphadenopathy presenting clinically with chest pain, persistent cough, dyspnea, wheezing, hoarseness, hemoptysis, loss of appetite, weight loss, and neurological and endocrine paraneoplastic syndromes. SCLC is primarily reported in elderly people with a history of long-term tobacco exposure."
      },
      "child_count": 6,
      "reference_id": "MONDO:0008433"
    }
  ],
  "children": [
    {
      "id": 2978,
      "label": "lung combined type small cell adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5365,
        6791
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050917",
          "GARD:0022792",
          "MEDGEN:231029",
          "NCIT:C9379",
          "UMLS:C1332165"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A lung combined type small cell carcinoma that has material basis in epithelial tissue of glandular origin."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000532"
    }
  ],
  "roots": [
    {
      "id": 7728,
      "label": "combined lung carcinoma"
    },
    {
      "id": 9726,
      "label": "small cell lung carcinoma"
    }
  ]
}