{
  "id": 5396,
  "label": "tanycytic ependymoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003474",
  "properties": {
    "xrefs": [
      "DOID:5504",
      "GARD:0023519",
      "MEDGEN:237159",
      "NCIT:C6903",
      "UMLS:C1370500"
    ],
    "synonyms": [
      "tanycytic ependymoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A variant of ependymoma, often found in the spinal cord, with tumor cells arranged in fascicles of variable width and cell density. Ependymal rosettes are generally absent, so this lesion must be distinguished from astrocytic neoplasms, but its EM characteristics are ependymal. (Adapted from WHO.)"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 17161,
      "label": "ependymoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5210,
        20695
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4844",
          "EFO:1000028",
          "GARD:0006353",
          "ICDO:9391/3",
          "MEDGEN:41825",
          "MESH:D004806",
          "MedDRA:10014967",
          "NANDO:2200088",
          "NCIT:C3017",
          "ONCOTREE:EPM",
          "Orphanet:251636",
          "UMLS:C0014474"
        ],
        "synonyms": [
          "benign ependymoma",
          "ependymoma",
          "WHO grade II ependymal neoplasm",
          "WHO grade II ependymal tumor",
          "WHO grade II ependymal tumour",
          "ependymoma, benign",
          "clear cell ependymoma (histologic variant)",
          "ependymoma, familial",
          "papillary ependymoma (histologic variant)",
          "tanycytic ependymoma (histologic variant)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A WHO grade II, slow growing tumor of children and young adults, usually located intraventricularly. It is the most common ependymal neoplasm. It often causes clinical symptoms by blocking cerebrospinal fluid pathways. Key histological features include perivascular pseudorosettes and ependymal rosettes. (WHO)"
      },
      "child_count": 16,
      "reference_id": "MONDO:0016698"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 17161,
      "label": "ependymoma"
    }
  ]
}