{
  "id": 5397,
  "label": "papillary ependymoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003475",
  "properties": {
    "xrefs": [
      "DOID:5505",
      "GARD:0023520",
      "ICDO:9393/3",
      "MEDGEN:90810",
      "NCIT:C4319",
      "UMLS:C0334578"
    ],
    "synonyms": [
      "papillary ependymoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A rare variant of ependymoma characterized by well formed papillae. Tumor cell processes abutting capillaries are usually GFAP-positive. Differential diagnoses include choroid plexus papilloma, papillary meningioma and metastatic papillary carcinoma. (Adapted from WHO)"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 17161,
      "label": "ependymoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5210,
        20695
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4844",
          "EFO:1000028",
          "GARD:0006353",
          "ICDO:9391/3",
          "MEDGEN:41825",
          "MESH:D004806",
          "MedDRA:10014967",
          "NANDO:2200088",
          "NCIT:C3017",
          "ONCOTREE:EPM",
          "Orphanet:251636",
          "UMLS:C0014474"
        ],
        "synonyms": [
          "benign ependymoma",
          "ependymoma",
          "WHO grade II ependymal neoplasm",
          "WHO grade II ependymal tumor",
          "WHO grade II ependymal tumour",
          "ependymoma, benign",
          "clear cell ependymoma (histologic variant)",
          "ependymoma, familial",
          "papillary ependymoma (histologic variant)",
          "tanycytic ependymoma (histologic variant)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A WHO grade II, slow growing tumor of children and young adults, usually located intraventricularly. It is the most common ependymal neoplasm. It often causes clinical symptoms by blocking cerebrospinal fluid pathways. Key histological features include perivascular pseudorosettes and ependymal rosettes. (WHO)"
      },
      "child_count": 16,
      "reference_id": "MONDO:0016698"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 17161,
      "label": "ependymoma"
    }
  ]
}