{
  "id": 5400,
  "label": "childhood ependymoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003478",
  "properties": {
    "xrefs": [
      "DOID:5509",
      "GARD:0023523",
      "MEDGEN:343609",
      "MESH:C531673",
      "NCIT:C8578",
      "UMLS:C1851584"
    ],
    "synonyms": [
      "ependymoma",
      "childhood ependymoma",
      "ependymoma of childhood",
      "paediatric ependymoma",
      "pediatric ependymoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "An ependymoma that arises from the central nervous system and occurs during childhood."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 17161,
      "label": "ependymoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5210,
        20695
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4844",
          "EFO:1000028",
          "GARD:0006353",
          "ICDO:9391/3",
          "MEDGEN:41825",
          "MESH:D004806",
          "MedDRA:10014967",
          "NANDO:2200088",
          "NCIT:C3017",
          "ONCOTREE:EPM",
          "Orphanet:251636",
          "UMLS:C0014474"
        ],
        "synonyms": [
          "benign ependymoma",
          "ependymoma",
          "WHO grade II ependymal neoplasm",
          "WHO grade II ependymal tumor",
          "WHO grade II ependymal tumour",
          "ependymoma, benign",
          "clear cell ependymoma (histologic variant)",
          "ependymoma, familial",
          "papillary ependymoma (histologic variant)",
          "tanycytic ependymoma (histologic variant)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A WHO grade II, slow growing tumor of children and young adults, usually located intraventricularly. It is the most common ependymal neoplasm. It often causes clinical symptoms by blocking cerebrospinal fluid pathways. Key histological features include perivascular pseudorosettes and ependymal rosettes. (WHO)"
      },
      "child_count": 16,
      "reference_id": "MONDO:0016698"
    },
    {
      "id": 20320,
      "label": "childhood neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:237153",
          "NCIT:C6283",
          "UMLS:C1368871"
        ],
        "synonyms": [
          "childhood neoplasm",
          "childhood neoplasm (disease)",
          "childhood tumor",
          "childhood tumour",
          "neoplasm (disease) of childhood",
          "paediatric neoplasm",
          "paediatric neoplasm (disease)",
          "paediatric tumour",
          "pediatric neoplasm",
          "pediatric neoplasm (disease)",
          "pediatric tumor"
        ],
        "definition": "A benign or malignant neoplasm arising during childhood."
      },
      "child_count": 14,
      "reference_id": "MONDO:0021079"
    }
  ],
  "children": [
    {
      "id": 6069,
      "label": "pediatric supratentorial ependymoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5400,
        8005,
        20096
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7502",
          "EFO:0008495",
          "GARD:0023899",
          "MEDGEN:78854",
          "NCIT:C9043",
          "UMLS:C0278650"
        ],
        "synonyms": [
          "supratentorial ependymoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An ependymoma that arises from the supratentorial region of the brain and occurs during childhood."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004249"
    }
  ],
  "roots": [
    {
      "id": 17161,
      "label": "ependymoma"
    },
    {
      "id": 20320,
      "label": "childhood neoplasm"
    }
  ]
}