{
  "id": 5414,
  "label": "squamous cell bile duct carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003500",
  "properties": {
    "xrefs": [
      "DOID:5537",
      "GARD:0023530",
      "MEDGEN:209017",
      "UMLS:C0861861"
    ],
    "synonyms": [
      "bile duct squamous cell carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A squamous cell carcinoma that involves the bile duct."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 7152,
      "label": "bile duct carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5049,
        18551
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4897",
          "EFO:0005540",
          "GARD:0024194",
          "MEDGEN:152840",
          "NCIT:C27814",
          "UMLS:C0740277"
        ],
        "synonyms": [
          "bile duct cancer",
          "bile duct cancer (including cholangiocarcinoma)",
          "bile duct carcinoma",
          "carcinoma of bile duct"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A carcinoma that arises from epithelial cells of the bile duct"
      },
      "child_count": 8,
      "reference_id": "MONDO:0005496"
    },
    {
      "id": 18553,
      "label": "squamous cell carcinoma of liver and intrahepatic biliary tract",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        18551
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021789",
          "MEDGEN:1668494",
          "Orphanet:424975",
          "UMLS:C4749400"
        ],
        "synonyms": [
          "squamous cell carcinoma of liver and IBT"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Squamous cell carcinoma of liver and intrahepatic biliary tract is an extremely rare, primary, malignant liver and biliray tract epithelial tumor originating in the intrahepatic bile duct epithelium histologically characterized by the presence of keratinization and/or intracellular bridges. Patients typically present abdominal pain in the right upper quadrant, jaundice, nausea, vomiting, anorexia, weight loss, fever and/or dyspepsia."
      },
      "child_count": 4,
      "reference_id": "MONDO:0018534"
    }
  ],
  "children": [
    {
      "id": 5453,
      "label": "adenosquamous bile duct carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5414,
        23670
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5624",
          "GARD:0023557",
          "MEDGEN:163666",
          "UMLS:C0861854"
        ],
        "synonyms": [
          "adenosquamous carcinoma of bile duct",
          "adenosquamous carcinoma of the bile duct",
          "bile duct adenosquamous carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An adenosquamous carcinoma that arises from the bile ducts."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003549"
    },
    {
      "id": 7758,
      "label": "extrahepatic bile duct squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5076,
        5414
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000248",
          "GARD:0024328",
          "NCIT:C5777"
        ],
        "synonyms": [
          "bile duct squamous cell carcinoma",
          "squamous cell bile duct carcinoma",
          "squamous cell carcinoma of bile duct",
          "squamous cell carcinoma of the bile duct",
          "extrahepatic bile duct squamous cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A carcinoma that arises from the extrahepatic bile ducts. It is composed entirely by malignant squamous epithelial cells."
      },
      "child_count": 6,
      "reference_id": "MONDO:0006203"
    }
  ],
  "roots": [
    {
      "id": 7152,
      "label": "bile duct carcinoma"
    },
    {
      "id": 18553,
      "label": "squamous cell carcinoma of liver and intrahepatic biliary tract"
    }
  ]
}