{
  "id": 5436,
  "label": "pancreatic gastrin-producing neuroendocrine tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003525",
  "properties": {
    "xrefs": [
      "DOID:5580",
      "GARD:0023548",
      "MEDGEN:235080",
      "MESH:D015408",
      "NCIT:C9069",
      "UMLS:C1368066"
    ],
    "synonyms": [
      "gastrin-producing neuroendocrine tumor of pancreas",
      "gastrin-producing neuroendocrine tumour of pancreas",
      "pancreas gastrin-producing neuroendocrine tumor",
      "pancreas gastrin-producing neuroendocrine tumour",
      "pancreatic G-cell tumour",
      "pancreatic gastrin producing NET",
      "pancreatic gastrin producing tumor",
      "pancreatic gastrin producing tumour",
      "pancreatic gastrin-producing neuroendocrine tumor",
      "islet cell tumor, ulcerogenic"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A usually malignant gastrin-producing neuroendocrine tumor arising from the pancreas. It may or may not be associated with inappropriate secretion of gastrin and an associated clinical syndrome."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 5434,
      "label": "gastrin-producing neuroendocrine tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2885
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5577",
          "GARD:0023546",
          "ICDO:8153/1",
          "MEDGEN:6551",
          "NANDO:2200395",
          "NCIT:C3050",
          "UMLS:C0017150",
          "icd11.foundation:1333125891"
        ],
        "synonyms": [
          "G cell tumor",
          "G cell tumour",
          "G-cell gastrin producing tumor",
          "G-cell gastrin producing tumour",
          "G-cell tumor",
          "G-cell tumour",
          "gastrin cell tumor",
          "gastrin secreting tumor",
          "gastrin secreting tumour",
          "gastrin-producing NET",
          "gastrin-producing neuroendocrine tumor",
          "gastrinoma",
          "malignant gastrinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A gastrin-producing neuroendocrine tumor. It is usually located in the pancreas but it is also found at other anatomic sites, including the stomach and small intestine."
      },
      "child_count": 3,
      "reference_id": "MONDO:0003523"
    },
    {
      "id": 19671,
      "label": "pancreatic neuroendocrine tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2885,
        7431
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000045",
          "GARD:0013034",
          "ICDO:8150/1",
          "MEDGEN:277875",
          "NCIT:C27720",
          "ONCOTREE:PANET",
          "Orphanet:97253",
          "UMLS:C1337011"
        ],
        "synonyms": [
          "islet cell tumor",
          "islet cell tumors - pancreas",
          "islet cell tumors of the pancreas",
          "islet cell tumour",
          "islet cell tumours - pancreas",
          "islet cell tumours of the pancreas",
          "pancreatic NET",
          "pancreatic neuroendocrine tumor",
          "well differentiated pancreatic endocrine neoplasm",
          "well differentiated pancreatic endocrine tumor",
          "well differentiated pancreatic endocrine tumour",
          "well-differentiated NEN of pancreas",
          "well-differentiated neuroendocrine neoplasm of pancreas",
          "well-differentiated pancreatic NEN",
          "well-differentiated pancreatic neuroendocrine neoplasm",
          "PANET",
          "neuroendocrine tumor of pancreas",
          "neuroendocrine tumour of pancreas",
          "pancreatic endocrine tumor",
          "pancreatic endocrine tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Pancreatic endocrine tumor, also known as pancreatic neuroendocrine tumor (PNET), describes a group of endocrine tumors originating in the pancreas that are usually indolent and benign, but may have the potential to be malignant. They can be functional, exhibiting a hormonal hypersecretion syndrome, but can be non-functional presenting with non-specific symptoms and include insulinoma, glucagonoma, VIPoma, somatostatinoma (SSoma), PPoma and Zollinger-Ellison syndrome (ZES, or gastrinoma) and other ectopic hormone producing tumors (such as GRFoma)."
      },
      "child_count": 22,
      "reference_id": "MONDO:0019954"
    }
  ],
  "children": [
    {
      "id": 21549,
      "label": "pancreatic gastrinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5436,
        21182
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025441",
          "MEDGEN:1849954",
          "NCIT:C95596",
          "UMLS:C5848106"
        ],
        "synonyms": [
          "pancreatic gastrinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neuroendocrine tumor arising from the pancreas. It is characterized by inappropriate secretion of gastrin and associated with Zollinger Ellison syndrome. The latter is characterized by the presence of peptic ulcer, gastroesophageal reflux disease, abdominal pain, diarrhea, and malabsorption."
      },
      "child_count": 0,
      "reference_id": "MONDO:0024638"
    }
  ],
  "roots": [
    {
      "id": 5434,
      "label": "gastrin-producing neuroendocrine tumor"
    },
    {
      "id": 19671,
      "label": "pancreatic neuroendocrine tumor"
    }
  ]
}