{
  "id": 5481,
  "label": "esophagus liposarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003586",
  "properties": {
    "xrefs": [
      "DOID:5694",
      "GARD:0023570",
      "MEDGEN:232163",
      "NCIT:C5705",
      "UMLS:C1333456"
    ],
    "synonyms": [
      "esophageal liposarcoma",
      "esophagus liposarcoma",
      "liposarcoma of esophagus",
      "liposarcoma of the esophagus",
      "liposarcoma of the oesophagus"
    ],
    "categories": [
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A malignant adipose tissue neoplasm of the esophagus, characterized by multivacuolated lipoblasts with hyperchromatic nuclei, a solid pattern of growth, and a rich vascular network. It arises from the mucosal and submucosal layers of the lower esophagus. Clinical presentation includes progressive dysphagia, nausea, throat discomfort, and foreign body sensation."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 3444,
      "label": "esophagus sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8953,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1114",
          "GARD:0022900",
          "MEDGEN:234233",
          "NCIT:C5341",
          "UMLS:C1333466"
        ],
        "synonyms": [
          "esophageal sarcoma",
          "esophagus sarcoma",
          "sarcoma of esophagus",
          "sarcoma of oesophagus",
          "sarcoma of the esophagus",
          "sarcoma of the oesophagus",
          "sarcoma, esophagus",
          "sarcoma, oesophagus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A malignant soft tissue neoplasm that arises from the esophagus. Representative examples include Kaposi sarcoma, leiomyosarcoma, rhabdomyosarcoma, and synovial sarcoma."
      },
      "child_count": 4,
      "reference_id": "MONDO:0001204"
    },
    {
      "id": 6790,
      "label": "liposarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4839,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3382",
          "EFO:0000569",
          "GARD:0006913",
          "ICD9:171.9",
          "ICDO:8850/3",
          "MEDGEN:44177",
          "MESH:D008080",
          "MedDRA:10024627",
          "NANDO:2200065",
          "NCIT:C3194",
          "NORD:1925",
          "ONCOTREE:LIPO",
          "Orphanet:69078",
          "SCTID:254829001",
          "UMLS:C0023827"
        ],
        "synonyms": [
          "lip sarcoma",
          "liposarcoma",
          "liposarcoma, malignant",
          "sarcoma of lip"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A usually painless malignant tumor that arises from adipose tissue. Microscopically, it may contain a spectrum of neoplastic adipocytes ranging from lipoblasts to pleomorphic malignant adipocytes. Morphologic variants include: well differentiated, dedifferentiated, pleomorphic, and myxoid liposarcoma. The metastatic potential is higher in less differentiated tumors."
      },
      "child_count": 38,
      "reference_id": "MONDO:0005060"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 3444,
      "label": "esophagus sarcoma"
    },
    {
      "id": 6790,
      "label": "liposarcoma"
    }
  ]
}