{
  "id": 5530,
  "label": "central nervous system hematopoietic neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003641",
  "properties": {
    "xrefs": [
      "DOID:5772",
      "GARD:0023597",
      "MEDGEN:234101",
      "NCIT:C5503",
      "UMLS:C1332882"
    ],
    "synonyms": [
      "CNS haematopoietic neoplasm",
      "CNS haematopoietic tumour",
      "CNS hematopoietic neoplasm",
      "CNS hematopoietic tumor",
      "central nervous system haematopoietic and lymphoid system neoplasm",
      "central nervous system haematopoietic neoplasms",
      "central nervous system haematopoietic tumour",
      "central nervous system hematopoietic and lymphoid system neoplasm",
      "central nervous system hematopoietic neoplasm",
      "central nervous system hematopoietic neoplasms",
      "central nervous system hematopoietic tumor",
      "haematopoietic and lymphoid system neoplasm of central nervous system",
      "haematopoietic neoplasm of CNS",
      "haematopoietic neoplasm of central nervous system",
      "haematopoietic neoplasm of the CNS",
      "haematopoietic neoplasm of the central nervous system",
      "haematopoietic tumour of central nervous system",
      "haematopoietic tumour of the central nervous system",
      "hematopoietic and lymphoid system neoplasm of central nervous system",
      "hematopoietic neoplasm of CNS",
      "hematopoietic neoplasm of central nervous system",
      "hematopoietic neoplasm of the CNS",
      "hematopoietic neoplasm of the central nervous system",
      "hematopoietic tumor of central nervous system",
      "hematopoietic tumor of the central nervous system",
      "lymphomas and hemopoietic neoplasms of CNS",
      "lymphomas and hemopoietic neoplasms of the CNS",
      "central nervous system hematologic cancer"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A primary or metastatic neoplasm of hematopoietic origin that affects the brain, meninges, or spinal cord. Representative examples include Hodgkin and non-Hodgkin lymphomas, histiocytic tumors, and leukemias."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 7694,
      "label": "central nervous system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4657,
        20456
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000158",
          "MEDGEN:88335",
          "NCIT:C9293",
          "UMLS:C0085136"
        ],
        "synonyms": [
          "CNS neoplasm",
          "CNS tumor",
          "CNS tumour",
          "brain/spinal cord tumor",
          "brain/spinal cord tumour",
          "central nervous system neoplasm",
          "central nervous system neoplasm (disease)",
          "central nervous system tumor",
          "central nervous system tumour",
          "neoplasm of CNS",
          "neoplasm of central nervous system",
          "neoplasm of the central nervous system",
          "tumor of CNS",
          "tumor of central nervous system",
          "tumor of the CNS",
          "tumor of the central nervous system",
          "tumour of CNS",
          "tumour of central nervous system",
          "tumour of the CNS",
          "tumour of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign or malignant, primary or metastatic neoplasm that affects the brain, meninges, or spinal cord. Representative examples of primary neoplasms include astrocytoma, oligodendroglioma, ependymoma, and meningioma. Representative examples of metastatic neoplasms include carcinoma and leukemia."
      },
      "child_count": 20,
      "reference_id": "MONDO:0006130"
    },
    {
      "id": 23467,
      "label": "hematopoietic and lymphoid cell neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4440
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025916",
          "MEDGEN:91264",
          "NCIT:C27134",
          "UMLS:C0376544"
        ],
        "synonyms": [
          "HEMOLYMPHORETICULAR tumor, malignant",
          "haematological neoplasm",
          "haematological tumour",
          "haematopoietic and lymphoid neoplasms",
          "haematopoietic cancer",
          "haematopoietic cell tumour",
          "haematopoietic malignancy, NOS",
          "haematopoietic neoplasm",
          "haematopoietic neoplasms including lymphomas",
          "haematopoietic tumour",
          "hematologic cancer",
          "hematologic malignancy",
          "hematologic neoplasm",
          "hematological neoplasm",
          "hematological tumor",
          "hematopoietic and lymphoid cell neoplasm",
          "hematopoietic and lymphoid neoplasms",
          "hematopoietic cancer",
          "hematopoietic cell tumor",
          "hematopoietic malignancy, NOS",
          "hematopoietic neoplasm",
          "hematopoietic neoplasms including lymphomas",
          "hematopoietic tumor",
          "hematopoietic, Including myeloma",
          "malignant haematopoietic neoplasm",
          "malignant hematologic neoplasm",
          "malignant hematopoietic neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A neoplasm arising from hematopoietic cells found in the bone marrow, peripheral blood, lymph nodes and spleen (organs of the hematopoietic system). Hematopoietic cell neoplasms can also involve other anatomic sites (e.g. central nervous system, gastrointestinal tract), either by metastasis, direct tumor infiltration, or neoplastic transformation of extranodal lymphoid tissues. The commonest forms are the various types of leukemia, Hodgkin and non-Hodgkin lymphomas, myeloproliferative neoplasms, and myelodysplastic syndromes."
      },
      "child_count": 8,
      "reference_id": "MONDO:0044881"
    }
  ],
  "children": [
    {
      "id": 3803,
      "label": "central nervous system leukemia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5530,
        6789
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12969",
          "GARD:0022972",
          "MEDGEN:234102",
          "NCIT:C5440",
          "UMLS:C1332884"
        ],
        "synonyms": [
          "CNS leukaemia",
          "CNS leukemia",
          "central nervous system leukaemia (disease)",
          "central nervous system leukemia",
          "central nervous system leukemia (disease)",
          "leukaemia (disease) of central nervous system",
          "leukaemia of CNS",
          "leukaemia of central nervous system",
          "leukaemia of the CNS",
          "leukaemia of the central nervous system",
          "leukemia (disease) of central nervous system",
          "leukemia of CNS",
          "leukemia of central nervous system",
          "leukemia of the CNS",
          "leukemia of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Leukemia infiltrating the central nervous system structures."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001606"
    },
    {
      "id": 4433,
      "label": "intracranial cavernous angioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4434,
        5125,
        5530
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2516",
          "GARD:0023117",
          "MEDGEN:232659",
          "NANDO:2200852",
          "NCIT:C5432",
          "SCTID:445513004",
          "UMLS:C1334237"
        ],
        "synonyms": [
          "intracranial cavernoma",
          "intracranial cavernous angioma",
          "intracranial cavernous hemangioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A cavernous hemangioma arising from the brain and meninges."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002327"
    },
    {
      "id": 4634,
      "label": "primary central nervous system lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3028,
        4753,
        5530,
        6694,
        17548,
        17660
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3234",
          "EFO:1000157",
          "GARD:0009318",
          "ICD9:200.5",
          "MEDGEN:79187",
          "MedDRA:10036685",
          "NCIT:C9301",
          "NORD:2002",
          "ONCOTREE:PCNSL",
          "Orphanet:46135",
          "SCTID:307649006",
          "UMLS:C0280803",
          "icd11.foundation:1133193893"
        ],
        "synonyms": [
          "CNS lymphoma",
          "PCNSL",
          "central nervous system lymphoma",
          "lymphoma of central nervous system",
          "malignant lymphomas of CNS",
          "malignant lymphomas of the CNS",
          "microglioma",
          "primary CNS lymphoma",
          "primary brain lymphoma",
          "primary central nervous system lymphoma",
          "primary lymphoma, CNS"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A non-Hodgkin or Hodgkin lymphoma that arises in the brain or spinal cord as a primary lesion. There is no evidence of lymphoma outside the central nervous system at the time of diagnosis."
      },
      "child_count": 18,
      "reference_id": "MONDO:0002571"
    },
    {
      "id": 8142,
      "label": "pituitary gland basophil adenoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5530,
        6569,
        7896
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4542",
          "EFO:1000834",
          "GARD:0024457",
          "ICDO:8300/0",
          "MEDGEN:1746",
          "MESH:D000237",
          "NCIT:C2856",
          "UMLS:C0001431"
        ],
        "synonyms": [
          "basophilic adenoma",
          "basophilic pituitary gland adenoma",
          "mucoid cell adenoma",
          "pituitary basophilic adenoma",
          "basophil adenoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An epithelial neoplasm of the anterior pituitary gland in which the neoplastic cells stain positive with basic dyes."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006673"
    }
  ],
  "roots": [
    {
      "id": 7694,
      "label": "central nervous system neoplasm"
    },
    {
      "id": 23467,
      "label": "hematopoietic and lymphoid cell neoplasm"
    }
  ]
}