{
  "id": 5553,
  "label": "extragonadal seminoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003668",
  "properties": {
    "xrefs": [
      "DOID:5838",
      "GARD:0023613",
      "MEDGEN:234243",
      "NCIT:C7327",
      "UMLS:C1333502"
    ],
    "synonyms": [
      "extragonadal primary seminoma",
      "extragonadal seminoma",
      "primary extragonadal seminoma"
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 5000,
      "label": "seminoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7832,
        20017
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4440",
          "GARD:0023322",
          "ICD9:186.9",
          "ICDO:9061/3",
          "MEDGEN:11371",
          "MESH:D018239",
          "NCIT:C9309",
          "ONCOTREE:SEM",
          "SCTID:443675005",
          "UMLS:C0036631"
        ],
        "synonyms": [
          "seminoma",
          "seminoma, malignant",
          "seminoma, pure"
        ],
        "definition": "A radiosensitive malignant germ cell tumor found in the testis (especially undescended), and extragonadal sites (anterior mediastinum and pineal gland). It is characterized by the presence of uniform cells with clear or dense cytoplasm which contains glycogen, and by a large nucleus which contains one or more nucleoli. The neoplastic germ cells form aggregates separated by fibrous septa. The fibrous septa contain chronic inflammatory cells, mainly lymphocytes."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003001"
    },
    {
      "id": 5094,
      "label": "extragonadal germ cell cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7832,
        18334
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4717",
          "GARD:0023371",
          "MEDGEN:235292",
          "NCIT:C8881",
          "UMLS:C1334581"
        ],
        "synonyms": [
          "extragonadal germ cell malignant tumour",
          "extragonadal germ cell tumor, malignant",
          "malignant extragonadal germ cell tumor",
          "malignant extragonadal germ cell tumour",
          "malignant neoplasm of extragonadal germ cell",
          "malignant neoplasm of the extragonadal germ cell",
          "malignant tumor of extragonadal germ cell",
          "malignant tumor of the extragonadal germ cell",
          "malignant tumour of extragonadal germ cell",
          "malignant tumour of the extragonadal germ cell",
          "tumour of extragonadal germ cell"
        ],
        "definition": "A malignant germ cell tumor that develops as a primary tumor in an anatomic site other than the testis or ovary."
      },
      "child_count": 18,
      "reference_id": "MONDO:0003113"
    }
  ],
  "children": [
    {
      "id": 5695,
      "label": "mediastinum seminoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5553,
        7838
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6249",
          "GARD:0023685",
          "MEDGEN:277355",
          "NCIT:C6812",
          "UMLS:C1334680"
        ],
        "synonyms": [
          "mediastinal seminoma",
          "mediastinum seminoma",
          "seminoma of mediastinum",
          "seminoma of the mediastinum"
        ],
        "definition": "An extragonadal malignant germ cell tumor that arises from the mediastinum. It is characterized by the presence of uniform cells with clear or eosinophilic cytoplasm, round nucleus with one or more nucleoli, and distinct cellular borders. It usually arises from the anterior mediastinum. It may present with respiratory distress, chest pain, or superior vena cava syndrome or it may be asymptomatic, with the tumor detected on routine chest x-ray. The prognosis of mediastinal pure seminomas is favorable compared to the mediastinal non-seminomatous malignant germ cell tumors."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003826"
    }
  ],
  "roots": [
    {
      "id": 5000,
      "label": "seminoma"
    },
    {
      "id": 5094,
      "label": "extragonadal germ cell cancer"
    }
  ]
}