{
  "id": 5595,
  "label": "bladder urachal squamous cell carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003714",
  "properties": {
    "xrefs": [
      "DOID:5957",
      "MEDGEN:307289",
      "NCIT:C39845",
      "UMLS:C1511206"
    ],
    "synonyms": [
      "bladder urachal squamous cell carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ]
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4794,
      "label": "bladder squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6727,
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3742",
          "EFO:1000130",
          "MEDGEN:124645",
          "NCIT:C4031",
          "ONCOTREE:BLSC",
          "SCTID:255111004",
          "UMLS:C0279681"
        ],
        "synonyms": [
          "bladder epidermoid carcinoma",
          "bladder squamous cell cancer",
          "bladder squamous cell carcinoma",
          "epidermoid carcinoma of bladder",
          "epidermoid carcinoma of the bladder",
          "epidermoid carcinoma of the urinary bladder",
          "epidermoid carcinoma of urinary bladder",
          "squamous cell carcinoma of bladder",
          "squamous cell carcinoma of the bladder",
          "squamous cell carcinoma of the urinary bladder",
          "squamous cell carcinoma of urinary bladder",
          "urinary bladder epidermoid carcinoma",
          "urinary bladder squamous cell carcinoma",
          "BLSC"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A squamous cell carcinoma of the bladder arising from metaplastic epithelium. It represents less than 10% of bladder carcinomas. The exception is the Middle East along the Nile Valley, where it represents the most common form of carcinoma because of the endemic nature of schistosomiasis. Bladder squamous cell carcinoma is often associated with long-standing chronic inflammation of the bladder and usually has a poor prognosis. The diagnosis of squamous cell carcinoma of the bladder should be reserved for those tumors that are predominantly keratin forming."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002760"
    },
    {
      "id": 5596,
      "label": "bladder urachal carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6727
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5958",
          "MEDGEN:419015",
          "MESH:C536475",
          "NCIT:C39842",
          "ONCOTREE:URCA",
          "Orphanet:695020",
          "UMLS:C2931202"
        ],
        "synonyms": [
          "bladder urachal cancer",
          "bladder urachal carcinoma",
          "urachal carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Urachal cancer is a type of bladder cancer, making up less than 1% of all bladder cancers. The urachus is a structure normally only present during development in the womb that connects the bellybutton and the bladder. This connection normally disappears before birth, but in some people remains. Urachalcancers are usually diagnosed in adults in their 50's and 60's and may develop at the dome or anterior wall of the bladder, along the midline of the body (including the belly button), and between the pubis symphasis and the bladder.Most urachal cancersare adenocarcinomas (cancers that develop from gland cells).Others may besarcomas (which develop from connective tissue -such as leiomyosarcoma, rhabdomyosarcoma, and malignant fibrous histiocytoma), small cell carcinomas, transitional cell cancer, and mixed neoplasias. Most individuals with urachal cancer have symptoms of with hematuria (blood in urine). Other symptoms may include abdominal pain, a palpable abdominal mass, mucinuria, and bacteriuria. Treatment usually involved surgery to remove the cancer."
      },
      "child_count": 3,
      "reference_id": "MONDO:0003715"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4794,
      "label": "bladder squamous cell carcinoma"
    },
    {
      "id": 5596,
      "label": "bladder urachal carcinoma"
    }
  ]
}