{
  "id": 5613,
  "label": "central nervous system mature teratoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003733",
  "properties": {
    "xrefs": [
      "DOID:6017",
      "GARD:0023638",
      "MEDGEN:234103",
      "NCIT:C7013",
      "ONCOTREE:BMT",
      "UMLS:C1332886"
    ],
    "synonyms": [
      "CNS mature teratoma",
      "central nervous system mature teratoma",
      "mature teratoma of CNS",
      "mature teratoma of central nervous system",
      "mature teratoma of the CNS",
      "mature teratoma of the central nervous system",
      "mature teratoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A teratoma composed exclusively of fully differentiated, 'adult-type' tissue elements that are sometimes arranged in a pattern resembling normal tissue relationships. Mitotic activity is low or absent. The more common ectodermal components present in a mature teratoma include skin, brain and choroid plexus. The more common mesodermal components include cartilage, bone, fat and muscle (both smooth and striated). And the most common endodermal components are cysts lined by epithelia of respiratory or enteric type and in some cases pancreatic or hepatic tissue. (Adapted from WHO)"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4757,
      "label": "central nervous system teratoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4656,
        19318,
        20012
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3640",
          "GARD:0020735",
          "MEDGEN:234105",
          "NANDO:2200104",
          "NCIT:C5441",
          "Orphanet:252018",
          "UMLS:C1332895"
        ],
        "synonyms": [
          "CNS teratoma",
          "central nervous system teratoma",
          "teratoma of CNS",
          "teratoma of central nervous system",
          "teratoma of the CNS",
          "teratoma of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A mature or immature teratoma that affects the central nervous system."
      },
      "child_count": 18,
      "reference_id": "MONDO:0002718"
    },
    {
      "id": 5430,
      "label": "mature teratoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4656
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5566",
          "GARD:0023544",
          "ICDO:9080/0",
          "MEDGEN:277967",
          "NANDO:2200105",
          "NCIT:C9015",
          "ONCOTREE:VMT",
          "SCTID:254875009",
          "UMLS:C1368910"
        ],
        "synonyms": [
          "mature teratoma"
        ],
        "definition": "A teratoma which may be cystic; it is composed entirely of well differentiated, adult-type tissues, without evidence of fetal-type tissues."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003517"
    }
  ],
  "children": [
    {
      "id": 5612,
      "label": "adult central nervous system mature teratoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5611,
        5613
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6016",
          "GARD:0023637",
          "MEDGEN:231037",
          "NCIT:C27400",
          "UMLS:C1332194"
        ],
        "synonyms": [
          "adult central nervous system mature teratoma",
          "central nervous system mature teratoma of adults"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A central nervous system mature teratoma that occurs in an adult."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003732"
    },
    {
      "id": 5739,
      "label": "childhood central nervous system mature teratoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5613,
        5630
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6423",
          "GARD:0023709",
          "MEDGEN:232345",
          "NCIT:C27404",
          "UMLS:C1332955"
        ],
        "synonyms": [
          "central nervous system mature teratoma of childhood",
          "childhood central nervous system mature teratoma",
          "paediatric central nervous system mature teratoma",
          "pediatric central nervous system mature teratoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A mature teratoma that arises from the central nervous system during childhood."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003875"
    },
    {
      "id": 5865,
      "label": "pineal region mature teratoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5613,
        5864
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6857",
          "GARD:0023778",
          "MEDGEN:233329",
          "NCIT:C6754",
          "UMLS:C1335417"
        ],
        "synonyms": [
          "mature teratoma of pineal area",
          "mature teratoma of pineal region",
          "mature teratoma of the pineal area",
          "mature teratoma of the pineal region",
          "pineal area mature teratoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0004016"
    }
  ],
  "roots": [
    {
      "id": 4757,
      "label": "central nervous system teratoma"
    },
    {
      "id": 5430,
      "label": "mature teratoma"
    }
  ]
}