{
  "id": 5772,
  "label": "mixed cell uveal melanoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003910",
  "properties": {
    "xrefs": [
      "DOID:6522",
      "EFO:1000380",
      "GARD:0023728",
      "MEDGEN:235330",
      "NCIT:C35781",
      "UMLS:C1334782"
    ],
    "synonyms": [
      "mixed cell uveal melanoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "A melanoma arising from the choroid, ciliary body, or the iris. It is characterized by the presence of a mixture of spindle A melanoma cells, spindle B melanoma cells, and epithelioid melanoma cells."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 7983,
      "label": "uveal melanoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4710,
        7858
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6039",
          "EFO:1000616",
          "GARD:0008621",
          "MEDGEN:65077",
          "MESH:C536494",
          "MedDRA:10061252",
          "NCIT:C7712",
          "OMIM:155720",
          "ONCOTREE:UM",
          "Orphanet:39044",
          "UMLS:C0220633"
        ],
        "synonyms": [
          "intraocular melanoma",
          "melanoma (disease) of uvea",
          "melanoma of the uvea",
          "melanoma of uvea",
          "melanoma, uveal, malignant",
          "uvea melanoma",
          "uvea melanoma (disease)",
          "uveal melanoma",
          "iris melanoma",
          "choroidal melanoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A melanoma derived from melanocytes of the uveal tract. It is the most common primary intraocular tumor in the United States and Western Europe. Similar to melanoma of the skin, it is rare in Africa and Asia. Diagnostic procedures include ophthalmoscopic exam, fluorescein angiography and ultrasound. Treatment includes: surgical excision of the eye, iridocyclectomy and tumor resection. Recent treatments also include radiotherapy or photo coagulation. Classification of uveal melanomas recognizes four cell types within these tumors: epithelioid, intermediate, mixed cell, and spindle cell types. The spindle cell type uveal melanomas are further sub-classified as spindle cell type A and spindle cell type B."
      },
      "child_count": 16,
      "reference_id": "MONDO:0006486"
    }
  ],
  "children": [
    {
      "id": 5773,
      "label": "ciliary body mixed cell melanoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5772,
        5774
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6523",
          "GARD:0023729",
          "MEDGEN:234150",
          "NCIT:C35783",
          "UMLS:C1333051"
        ],
        "synonyms": [
          "ciliary body mixed cell melanoma",
          "ciliary body mixed cell uveal melanoma",
          "mixed cell uveal melanoma of ciliary body"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A mixed cell uveal melanoma that involves the ciliary body."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003911"
    },
    {
      "id": 5775,
      "label": "choroid mixed cell melanoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5741,
        5772
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6525",
          "GARD:0023731",
          "MEDGEN:232361",
          "NCIT:C35782",
          "UMLS:C1333025"
        ],
        "synonyms": [
          "choroid mixed cell melanoma",
          "mixed cell uveal melanoma of optic choroid",
          "optic choroid mixed cell uveal melanoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A mixed cell uveal melanoma that involves the optic choroid."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003913"
    }
  ],
  "roots": [
    {
      "id": 7983,
      "label": "uveal melanoma"
    }
  ]
}