{
  "id": 5776,
  "label": "cortical thymoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003915",
  "properties": {
    "xrefs": [
      "DOID:6530",
      "GARD:0023732",
      "ICDO:8584/1",
      "MEDGEN:224762",
      "NCIT:C6888",
      "UMLS:C1266095"
    ],
    "synonyms": [
      "cortical thymoma",
      "polygonal cell thymoma",
      "thymoma type B2"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A thymic epithelial neoplasm characterized by the presence of neoplastic large, polygonal epithelial cells with large vesicular nuclei and prominent nucleoli. The neoplastic cells are arranged around perivascular spaces and along septa. Immature T-lymphocytes are also present. It may be associated with myasthenia gravis, pure red cell aplasia, and hypogammaglobulinemia. It is a tumor of moderate malignancy. The majority of cases occur in the anterior mediastinum as Masaoka stage I, stage II, or stage III tumors. Metastatic, stage IV tumors occur less frequently."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 17386,
      "label": "thymoma type B",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6569,
        7959
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3282",
          "GARD:0020893",
          "MEDGEN:231253",
          "NCIT:C7114",
          "Orphanet:263317",
          "UMLS:C1328042"
        ],
        "synonyms": [
          "Dendritic cell thymoma",
          "dendritic cell thymoma",
          "dendritic cell thymoma (disease)",
          "epithelioid thymoma",
          "plump cell thymoma",
          "primary thymic epithelial neoplasm type B",
          "primary thymic epithelial tumor type B",
          "primary thymic epithelial tumour type B",
          "thymoma type B"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An epithelial neoplasm arising from the thymus. It may be associated with myasthenia gravis, pure red cell aplasia, and hypogammaglobulinemia. It includes thymoma type B1 which is a thymoma of low grade malignant potential, thymoma type B2 which is a thymoma of moderate malignancy, and thymoma type B3 which is also known as well differentiated thymic carcinoma."
      },
      "child_count": 6,
      "reference_id": "MONDO:0016974"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 17386,
      "label": "thymoma type B"
    }
  ]
}