{
  "id": 5793,
  "label": "breast apocrine carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003934",
  "properties": {
    "xrefs": [
      "DOID:6581",
      "GARD:0027657",
      "MEDGEN:272319",
      "NCIT:C5141",
      "UMLS:C1332316"
    ],
    "synonyms": [
      "apocrine adenocarcinoma of breast",
      "apocrine breast carcinoma",
      "apocrine carcinoma of breast",
      "apocrine carcinoma of the breast",
      "breast apocrine adenocarcinoma",
      "breast apocrine carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0002657",
        "name": "breast disorder"
      }
    ],
    "definition": "An adenocarcinoma of the breast characterized by the presence of two intermingled cellular components: cells with abundant granular, eosinophilic cytoplasm, and cells with abundant cytoplasm containing fine empty vacuoles."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 5169,
      "label": "apocrine adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5170,
        7178
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4933",
          "GARD:0012138",
          "ICDO:8401/3",
          "MEDGEN:569650",
          "NCIT:C4169",
          "UMLS:C0334346"
        ],
        "synonyms": [
          "apocrine adenocarcinoma (morphologic abnormality)",
          "apocrine carcinoma",
          "apocrine gland adenocarcinoma",
          "apocrine gland carcinoma",
          "carcinoma of apocrine gland"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A carcinoma with apocrine differentiation arising from the sweat glands. It presents as single or multiple nodular lesions which may be ulcerated or hemorrhagic and is usually in the axilla and less often in the anogenital region. It grows in the dermis and infiltrates subcutaneous tissues. It is characterized by the presence of large cells with abundant eosinophilic cytoplasm and large often vesicular nuclei. Most cases are slow growing tumors and have a prolonged course."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003214"
    },
    {
      "id": 7234,
      "label": "breast ductal adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6729
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3007",
          "EFO:0006318",
          "MEDGEN:315942",
          "MESH:D018270",
          "NCIT:C4017",
          "UMLS:C1527349"
        ],
        "synonyms": [
          "duct adenocarcinoma",
          "duct carcinoma",
          "ductal adenocarcinoma",
          "ductal carcinoma",
          "breast ductal carcinoma",
          "ductal breast adenocarcinoma",
          "ductal breast carcinoma",
          "ductal carcinoma of breast",
          "ductal carcinoma of the breast",
          "mammary duct adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A breast carcinoma arising from the ducts. While ductal carcinomas can arise at other sites, this term is universally used to refer to carcinomas of the breast. Ductal carcinomas account for about two thirds of all breast cancers. Two types of ductal carcinomas have been described: ductal carcinoma in situ (DCIS) and invasive ductal carcinoma. The latter often spreads to the axillary lymph nodes and other anatomic sites. The two forms of ductal carcinoma often coexist."
      },
      "child_count": 4,
      "reference_id": "MONDO:0005590"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 5169,
      "label": "apocrine adenocarcinoma"
    },
    {
      "id": 7234,
      "label": "breast ductal adenocarcinoma"
    }
  ]
}