{
  "id": 5819,
  "label": "Froelich syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003962",
  "properties": {
    "xrefs": [
      "DOID:6676",
      "ICD9:253.8",
      "MEDGEN:4795",
      "NCIT:C34625",
      "SCTID:62999006",
      "UMLS:C0016724"
    ],
    "synonyms": [
      "Babinski-Froelich syndrome",
      "Froehlich's syndrome",
      "Froelich's syndrome",
      "Frohlich syndrome",
      "Frohlich's syndrome",
      "Frolich's syndrome",
      "Fröhlich syndrome",
      "Launois-Cleret syndrome",
      "dystrophia Adiposogenitalis",
      "hypothalamic infantilism-obesity",
      "sexual infantilism",
      "Adiposodysgenesis",
      "Froelich's adiposity",
      "adiposogenital dystrophy"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Froelich syndrome is characterized by obesity and hypogonadism due to a hypothalamic-pituitary disorder. The hypothalamus is a part of the brain where certain functions such as sleep cycles and body temperature are regulated. The pituitary is a gland that makes hormones that affect growth and the functions of other glands in the body. Froehlich syndrome is acquired(i.e., not thought to be inherited or genetic). This syndrome appears to affect males more commonly. The term 'Froelich syndrome' is rarely used today."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4280,
      "label": "hypothalamic disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5067
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1931",
          "ICD9:253.9",
          "MEDGEN:6988",
          "MESH:D007027",
          "SCTID:399100005",
          "UMLS:C0020655"
        ],
        "synonyms": [
          "disease of hypothalamus",
          "disease or disorder of hypothalamus",
          "disorder of hypothalamus",
          "hypothalamus disease",
          "hypothalamus disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Neoplastic, inflammatory, infectious, and other diseases of the hypothalamus. Clinical manifestations include appetite disorders; autonomic nervous system diseases; sleep disorders; behavioral symptoms related to dysfunction of the limbic system; and neuroendocrine disorders."
      },
      "child_count": 3,
      "reference_id": "MONDO:0002150"
    },
    {
      "id": 4370,
      "label": "syndromic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:225",
          "MEDGEN:11688",
          "MESH:D013577",
          "NCIT:C28193",
          "OGMS:0000086",
          "UMLS:C0039082"
        ],
        "synonyms": [
          "cluster, symptom",
          "clusters, symptom",
          "symptom cluster",
          "symptom clusters",
          "syndrome",
          "syndrome associated with disease or disorder",
          "syndromes",
          "syndromic disease",
          "syndromic disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A group of signs, symptoms, and clinicopathological characteristics that may or may not have a genetic basis and collectively define an abnormal condition."
      },
      "child_count": 1182,
      "reference_id": "MONDO:0002254"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4280,
      "label": "hypothalamic disorder"
    },
    {
      "id": 4370,
      "label": "syndromic disease"
    }
  ]
}