{
  "id": 5832,
  "label": "malignant type AB thymoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003976",
  "properties": {
    "xrefs": [
      "DOID:6723",
      "GARD:0023758",
      "ICDO:8582/3",
      "MEDGEN:224760",
      "NCIT:C6886",
      "UMLS:C1266093"
    ],
    "synonyms": [
      "malignant thymoma type AB",
      "malignant type AB thymoma",
      "thymoma type AB, malignant"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A type AB thymoma which is characterized by an aggressive clinical course (capsular invasion, infiltration of the surrounding tissues) and can metastasize."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7956,
      "label": "thymic carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4646,
        6734,
        18240
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3284",
          "DOID:4554",
          "EFO:1000576",
          "GARD:0019695",
          "ICDO:8586/3",
          "MEDGEN:60049",
          "MedDRA:10061031",
          "NANDO:2200079",
          "NCIT:C7569",
          "NCIT:C7612",
          "ONCOTREE:THYC",
          "Orphanet:99868",
          "SCTID:444374006",
          "UMLS:C0205969",
          "icd11.foundation:1351671383"
        ],
        "synonyms": [
          "carcinoma of thymus",
          "malignant thymoma",
          "thymic carcinoma",
          "thymic carcinoma (excluding well differentiated thymic carcinoma)",
          "thymic carcinoma excluding well differentiated thymic carcinoma",
          "thymoma type C",
          "thymoma, malignant",
          "thymoma, malignant (morphologic abnormality)",
          "thymoma, type C (morphologic abnormality)",
          "thymus carcinoma",
          "type C thymoma",
          "THYC"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Thymic carcinoma (TC) is a type of thymic epithelial neoplasm characterized by a high malignant potential."
      },
      "child_count": 27,
      "reference_id": "MONDO:0006451"
    },
    {
      "id": 17387,
      "label": "thymoma type AB",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7959
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3280",
          "EFO:1000582",
          "GARD:0020894",
          "ICDO:8582/1",
          "MEDGEN:220414",
          "NCIT:C6885",
          "Orphanet:263324",
          "UMLS:C1266092"
        ],
        "synonyms": [
          "mixed type thymoma",
          "primary thymic epithelial neoplasm type AB",
          "primary thymic epithelial tumor type AB",
          "primary thymic epithelial tumour type AB",
          "thymoma type AB"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A thymic epithelial neoplasm characterized by the presence of a lymphocyte-poor component similar to that seen in type A thymoma and a lymphocyte-rich component which contains neoplastic small polygonal epithelial cells. It may be associated with myasthenia gravis and pure red cell aplasia. The majority of cases occur in the anterior mediastinum as Masaoka stage I tumors. A minority of the cases occur as stage II or stage III tumors. The overall survival is reported to be 80-100% at 5 and 10 years."
      },
      "child_count": 1,
      "reference_id": "MONDO:0016975"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7956,
      "label": "thymic carcinoma"
    },
    {
      "id": 17387,
      "label": "thymoma type AB"
    }
  ]
}