{
  "id": 5868,
  "label": "mediastinal gray zone lymphoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004020",
  "properties": {
    "xrefs": [
      "DOID:6867",
      "GARD:0023780",
      "MEDGEN:233679",
      "NCIT:C37870",
      "UMLS:C1334657"
    ],
    "synonyms": [
      "mediastinal B-cell lymphoma, unclassifiable, with features Intermediate between diffuse large B-cell lymphoma and Classic Hodgkin lymphoma",
      "mediastinal B-cell lymphoma, unclassifiable, with features Intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma",
      "mediastinal Gray zone lymphoma",
      "mediastinal Grey zone lymphoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A mediastinal lymphoma with molecular, morphologic, immunophenotypic, and clinical features of both mediastinal (thymic) large B-cell lymphoma and classical Hodgkin lymphoma. The identification of this group of lymphomas, along with recent gene expression profiling results (PDL2 gene expression in both mediastinal (thymic) large B-cell lymphoma tissues and Hodgkin lymphoma cell lines), further supports the hypothesis that mediastinal (thymic) large B-cell lymphomas and classical Hodgkin lymphomas are related entities."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 5545,
      "label": "B-cell lymphoma, unclassifiable, with features intermediate between diffuse large b-cell lymphoma and classical Hodgkin lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5822",
          "GARD:0010897",
          "ICDO:9596/3",
          "MEDGEN:234323",
          "NCIT:C37869",
          "UMLS:C1333878"
        ],
        "synonyms": [
          "B-cell lymphoma, unclassifiable, with features Intermediate between diffuse large B-cell lymphoma and Classic Hodgkin lymphoma",
          "B-cell lymphoma, unclassifiable, with features Intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma",
          "Gray zone lymphoma",
          "Grey zone lymphoma",
          "Hodgkin-like anaplastic large cell lymphoma",
          "large B-cell lymphoma with Hodgkin features"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A group of lymphomas displaying molecular, morphologic, immunophenotypic, and clinical overlap between classical Hodgkin lymphoma and diffuse large B-cell lymphoma. This term particularly applies to mediastinal lymphomas with overlapping features of mediastinal (thymic) large B-cell lymphoma and classical Hodgkin lymphoma."
      },
      "child_count": 1,
      "reference_id": "MONDO:0003658"
    },
    {
      "id": 5869,
      "label": "mediastinal malignant lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792,
        7455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6868",
          "GARD:0023781",
          "MEDGEN:235311",
          "NCIT:C6633",
          "UMLS:C1334665"
        ],
        "synonyms": [
          "lymphoma of mediastinum",
          "lymphoma of the mediastinum",
          "mediastinal lymphoma",
          "mediastinal malignant lymphoma",
          "mediastinum lymphoma",
          "primary mediastinal lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A lymphoma that arises from the mediastinum. Representative examples include mediastinal (thymic) large B-cell lymphoma and Hodgkin lymphoma."
      },
      "child_count": 4,
      "reference_id": "MONDO:0004021"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 5545,
      "label": "B-cell lymphoma, unclassifiable, with features intermediate between diffuse large b-cell lymphoma and classical Hodgkin lymphoma"
    },
    {
      "id": 5869,
      "label": "mediastinal malignant lymphoma"
    }
  ]
}