{
  "id": 5876,
  "label": "eye lymphoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004034",
  "properties": {
    "xrefs": [
      "DOID:6903",
      "GARD:0023787",
      "MEDGEN:1788822",
      "NCIT:C35690",
      "UMLS:C0730306"
    ],
    "synonyms": [
      "eye lymphoma",
      "eyeball of camera-type eye lymphoma",
      "lymphoma of eyeball of camera-type eye",
      "primary eye lymphoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "A lymphoma that involves the eye."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 4353,
      "label": "ocular cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3050,
        7266,
        20431
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2174",
          "ICD9:190.8",
          "ICD9:239.89",
          "MEDGEN:105418",
          "MESH:D005134",
          "NCIT:C4767",
          "SCTID:371486001",
          "UMLS:C0496836"
        ],
        "synonyms": [
          "eye neoplasm",
          "neoplasm of eye",
          "ocular tumor",
          "ocular tumour",
          "cancer of eye",
          "cancer of eyeball of camera-type eye",
          "cancer of the eye",
          "eye cancer",
          "eye neoplasm, malignant",
          "eyeball of camera-type eye cancer",
          "malignant eye neoplasm",
          "malignant eye tumor",
          "malignant eye tumour",
          "malignant eyeball of camera-type eye neoplasm",
          "malignant neoplasm of eye",
          "malignant neoplasm of eyeball of camera-type eye",
          "malignant neoplasm of the eye",
          "malignant ocular neoplasm",
          "malignant ocular tumor",
          "malignant ocular tumour",
          "malignant tumor of eye",
          "malignant tumor of the eye",
          "malignant tumour of eye",
          "malignant tumour of the eye",
          "neoplasm of eye proper"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A benign or malignant neoplasm affecting the structures of the eye."
      },
      "child_count": 30,
      "reference_id": "MONDO:0002236"
    },
    {
      "id": 6792,
      "label": "lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6881,
        16514
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060058",
          "EFO:0000574",
          "ICD9:200.0",
          "ICD9:200.1",
          "ICD9:202.80",
          "ICDO:9590/3",
          "MEDGEN:44223",
          "MESH:D008223",
          "MedDRA:10025310",
          "NANDO:2100004",
          "NCIT:C3208",
          "ONCOTREE:MLYM",
          "Orphanet:223735",
          "SCTID:118600007",
          "UMLS:C0024299"
        ],
        "synonyms": [
          "lymphoma",
          "lymphoma (Hodgkin and non-Hodgkin)",
          "lymphoma (Hodgkin's and non-Hodgkin's)",
          "lymphoma, malignant",
          "lymphomatous",
          "malignant lymphoma",
          "MLYM"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A malignant (clonal) proliferation of B- lymphocytes or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites. This category includes Non-Hodgkin lymphomas and Hodgkin lymphomas."
      },
      "child_count": 54,
      "reference_id": "MONDO:0005062"
    }
  ],
  "children": [
    {
      "id": 6163,
      "label": "retina lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5060,
        5876
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:774",
          "GARD:0023950",
          "ICD9:198.4",
          "MEDGEN:83291",
          "NCIT:C4365",
          "SCTID:232075002",
          "UMLS:C0339556"
        ],
        "synonyms": [
          "lymphoma of retina",
          "lymphoma of the retina",
          "primary retinal lymphoma",
          "retina lymphoma",
          "retinal lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A lymphoma that involves the retina."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004349"
    },
    {
      "id": 6165,
      "label": "intraocular lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5876,
        17548
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:775",
          "GARD:0021063",
          "ICD9:200.50",
          "MEDGEN:79344",
          "MESH:D064090",
          "NCIT:C9184",
          "Orphanet:279904",
          "SCTID:420788006",
          "UMLS:C0281658"
        ],
        "synonyms": [
          "PIOL",
          "intraocular lymphoma",
          "primary intraocular lymphoma",
          "primary intraocular non-Hodgkin's lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A lymphoma that arises within the eye. Signs and symptoms include decreased vision, uveitis, and vitreous floaters."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004351"
    },
    {
      "id": 17547,
      "label": "primary oculocerebral lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5876,
        17548
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021062",
          "MEDGEN:1814439",
          "Orphanet:279897",
          "UMLS:C5679779",
          "icd11.foundation:446504143"
        ],
        "synonyms": [
          "primary oculocerebral non-Hodgkin lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Primary oculocerebral lymphoma is a rare, primary, organ-specific, extranodal non-Hodgkin's lymphoma (typically diffuse large B-cell lymphoma), simultaneously affecting the intraocular compartments (retina, vitreous, optic nerve, uvea and others) and the central nervous system (commonly the cerebellum, spinal cord or pia mater). The presenting symptoms vary depending on the localization of the tumor and may include vitreous floaters or blurred vision, raised intracranial pressure (headache, vomiting, papilledema) and/or focal neurological deficits."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017205"
    },
    {
      "id": 18114,
      "label": "primary lymphoma of the conjunctiva",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5378,
        5876,
        17548
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021426",
          "MEDGEN:1635420",
          "NCIT:C175432",
          "Orphanet:319667",
          "SCTID:763477007",
          "UMLS:C4706485"
        ],
        "synonyms": [
          "conjunctiva lymphoma",
          "conjunctiva primary organ-specific lymphoma",
          "lymphoma of conjunctiva",
          "primary lymphoid conjunctival tumor",
          "primary lymphoid conjunctival tumour",
          "primary organ-specific lymphoma of conjunctiva"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Primary lymphoma of the conjunctiva is an extremely rare clonal lymphoid proliferation of the ocular surface, with an indolent course. Clinically it presents with treatment-resistant conjunctivitis, ptosis, excessive tear production or as a painless, salmon-pink, ''fleshy'' patch, with a smooth or multinodular surface, on the bulbar conjunctiva. Histologically it is usually B-cell Non-Hodgkin lymphoma (most often extranodal marginal zone B-cell lymphoma, followed by follicular and diffuse large B-cell lymphoma), with conjunctival T-cell Non-Hodgkin lymphoma being very rare."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017907"
    },
    {
      "id": 26273,
      "label": "primary vitreoretinal large b-cell lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3028,
        5876,
        18833
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "Orphanet:695631"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0979292"
    }
  ],
  "roots": [
    {
      "id": 4353,
      "label": "ocular cancer"
    },
    {
      "id": 6792,
      "label": "lymphoma"
    }
  ]
}